A flexible, multi-product, multi-technology, expandable facility for manufacturing products, such as biologicals, pharmaceuticals, or chemicals, and manufacturing processes using elements of such a facility.
대표청구항▼
1. A clean room system, comprising: a housing;a movable corridor;a first modular unit movably disposed within the housing and connected with the movable corridor, the first modular unit comprising: a first gowning area located at an end of the first modular unit proximate to the movable corridor;a f
1. A clean room system, comprising: a housing;a movable corridor;a first modular unit movably disposed within the housing and connected with the movable corridor, the first modular unit comprising: a first gowning area located at an end of the first modular unit proximate to the movable corridor;a first controlled air, sealable, sterilizable clean room within the first modular unit, the clean room having a first entry point for personnel from the movable corridor through the first gowning area;a first utility room within the first modular unit at an end of the first modular unit distal to the movable corridor, the first utility room having a first point of entry for personnel that is separate from the first clean room entry point, wherein the first utility room is configured to be serviced without entering the first clean room; anda first HVAC system within the first utility room, the first HVAC system connected with the first clean room via a first supply air duct and a first return air duct, the first HVAC system connected to a central HVAC air-handling unit located within the housing; anda second modular unit movably disposed within the housing and connected with the movable corridor, the second modular unit comprising: a second gowning area located at an end of the second modular unit proximate to the movable corridor;a second controlled air, sealable, sterilizable clean room within the second modular unit, the clean room having a second entry point for personnel from the movable corridor through the second gowning area;a second utility room within the second modular unit at an end of the second modular unit distal to the movable corridor, the second utility room having a second point of entry for personnel that is separate from the second clean room entry point, wherein the second utility room is configured to be serviced without entering the second clean room or the movable corridor; anda second HVAC system within the second utility room, the second HVAC system connected with the second clean room via a second supply air duct and a second return air duct, the second HVAC system connected to the central HVAC air-handling unit. 2. The clean room system of claim 1, wherein the first modular unit comprises one or more flexible connectors for supplying the first clean room with steam. 3. The clean room system of claim 1, further comprising one or more flexible connectors for connecting the first modular unit to water, gas, cooling, and heating supplies. 4. The clean room system of claim 1, further comprising a water filtration unit located in the utility room. 5. The clean room system of claim 1, further comprising a bioreactor in the first modular unit. 6. The clean room system of claim 5, wherein the bioreactor includes at least one of a liquid handling device, a refrigerator, a tissue culture hood, or microbiology testing equipment. 7. The clean room system of claim 1, further comprising a protein unit in the second modular unit. 8. The clean room system of claim 7, wherein the protein unit includes at least one of a centrifuge, a liquid chromatography column, a spectrophotometer, or a polyacrylamide gel electrophoresis (PAGE) unit. 9. The clean room system of claim 1, further comprising a purification system in the first modular unit. 10. The clean room system of claim 1, wherein the first and second modular units are parallel to one another and project in a same direction from the movable corridor. 11. The clean room system of claim 10, wherein the first and second modular units are of equal to length to one another, distal ends of the first and second modular units being aligned. 12. The clean room system of claim 1, further comprising means for permitting movement of the first modular unit within the housing, the means for permitting movement of the first modular unit positioned under the first modular unit. 13. The clean room system of claim 12, further comprising means for permitting movement of the second modular unit within the housing, the means for permitting movement of the second modular unit positioned under the second modular unit.
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