A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly co
A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site. The prosthetic valve further comprises a valve member configured to be quickly connected to the support structure. The support structure may take the form of a stent that is expanded at the site of a native valve. If desired, the native leaflets may remain and the stent may be used to hold the native valve open. In this case, the stent may be balloon expandable and configured to resist the powerful recoil force of the native leaflets. The support structure is provided with a coupling means for attachment to the valve member, thereby fixing the position of the valve member in the body. The valve member may be a non-expandable type, or may be expandable from a compressed state to an expanded state. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment.
대표청구항▼
1. A replacement prosthetic heart valve, comprising: an expandable anchoring member sized to contact a heart valve annulus in an expanded state and defining a lumen having an inner diameter, the anchoring member having a circular cross-section and a length such that the anchoring member may be expan
1. A replacement prosthetic heart valve, comprising: an expandable anchoring member sized to contact a heart valve annulus in an expanded state and defining a lumen having an inner diameter, the anchoring member having a circular cross-section and a length such that the anchoring member may be expanded within a native valve annulus to the push aside valvular leaflets of the native valve; anda one-way valve member comprising a non-expandable/non-collapsible support frame and defining an exterior dimension sized to fit within the lumen of the anchoring member, the valve member and anchoring member being configured to engage each other and hold the valve member within the lumen. 2. The heart valve of claim 1, wherein the anchoring member comprises a stent having a wider outflow end than an inflow end, and wherein the valve member comprises a base ring surrounding an inflow end thereof, the base ring being sized to fit within the outflow end of the stent. 3. The heart valve of claim 2, wherein the anchoring member further has a circular ridge formed along a transition region between the wider outflow end and inflow end, the ridge being smaller than the valve member exterior dimension so that the valve member seats on the ridge. 4. The heart valve of claim 3, wherein the ridge incorporates a support wire for strength. 5. The heart valve of claim 4, wherein the support wire has a radiopaque marker. 6. The heart valve of claim 1, wherein the anchoring member is provided with a groove formed in an inwardly-directed circumferential member that extends at least partially around the lumen of the anchoring member and is sized to receive a ring portion of the valve member. 7. The heart valve of claim 6, wherein the valve member comprises a non-expandable support frame from which the ring portion extends, and the ring portion forms a snap-fit with the groove. 8. The heart valve of claim 6, wherein the ring portion is configured to expand into the groove after deployment within the anchoring member. 9. The heart valve of claim 1, wherein the valve member comprises a peripheral ring portion and the anchoring member has a plurality of prongs that extend inward therefrom into the lumen to capture the ring portion of the valve member. 10. The heart valve of claim 9, wherein there are two rows of spaced-apart prongs that are each angled inward and toward the other row of prongs, and wherein the prongs are flexible to permit passage of the ring portion of the valve member into the space between the rows. 11. The heart valve of claim 10, wherein each of the prongs terminates in an enlarged head to prevent damage to the base ring. 12. The heart valve of claim 1, wherein the anchoring member comprises an outer sealing ring to help prevent leakage around the anchoring member. 13. The heart valve of claim 12, wherein the valve member includes a suture-permeable base ring surrounding an inflow end thereof, and the anchoring member comprises a suture-permeable fixation ring attached within the lumen. 14. The heart valve of claim 13, wherein the valve member connects to the anchoring member via sutures looped between the base ring and the fixation ring. 15. The heart valve of claim 1, wherein the valve member includes a suture-permeable base ring surrounding an inflow end thereof, and the anchoring member comprises a suture-permeable fixation ring attached within the lumen, wherein the valve member connects to the anchoring member via sutures looped between the base ring and the fixation ring. 16. The heart valve of claim 15, wherein the base ring and the fixation ring comprise silicone rubber. 17. The heart valve of claim 15, wherein the base ring and the fixation ring comprise rolled up fabric cuffs. 18. The heart valve of claim 1, wherein the support frame defines a plurality of alternating cusps and upstanding commissures that support flexible leaflets. 19. The heart valve of claim 18, wherein the flexible leaflets are bovine pericardial leaflets. 20. The heart valve of claim 1, wherein the valve member is configured to be detached from within the anchoring member while implanted and replaced with another valve member.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (218)
Hinnenkamp Thomas F., Adjustable sizing apparatus.
Hinnenkamp Thomas F. ; Blazei Mark A. ; Kagan Jonathan ; Packard Brian M. ; Smelser Ricci D. ; Costello David M. ; Hillyard Angela L. ; Hidani Tim T., Adjustable sizing apparatus.
Case, Brian C.; Flagle, Jacob A.; Hoffa, Andrew K.; Schaeffer, Darin G.; Garrison, Michael L., Artificial valve prosthesis with improved flow dynamics.
Colvin David P. (Apex NC) Whitney Raymond A. (Raleigh NC) Marsh Bernard R. (Upperco MD) Kline William M. (Gloversville NY) Rizzo Ronald R. (Gloversville NY) Orlosky Mark E. (Gloversville NY), Body lumen measuring instrument.
Donlon Brian S. (Los Altos Hills CA) Mueller ; Jr. Richard L. (Byron CA) Daniel S. Christopher (San Francisco CA) Gifford ; III Hanson S. (Woodside CA) Stevens John H. (London GB2), Clamp assembly and method of use.
Malecki William W. (San Francisco CA) Sterman Wesley D. (San Francisco CA) Gifford ; III Hanson S. (Woodside CA) Miller Scott H. (Sunnyvale CA), Clamp assembly and method of use.
Krueger Kurt D. ; DeLeon Averdon M. ; Nettekoven William S. ; Anderson Kimberly A. ; Girard Michael J., Combined holder tool and rotator for a prosthetic heart valve.
Gurskis, Donnell W.; Ino, Takashi Harry; Lane, Ernest; Bacich, Steven R., Connection systems for two piece prosthetic heart valve assemblies and methods for making and using them.
Sterman Wesley D. (San Francisco CA) Garrison Michi E. (Belmont CA) Gifford ; III Hanson S. (Woodside CA) Stevens John H. (Palo Alto CA), Devices and methods for intracardiac procedures.
Skelton John (Sharon MA) Clark Richard E. (St. Louis MO) Davis Robert B. (Framingham MA), Elastomeric sheet materials for heart valve and other prosthetic implants.
Williamson ; IV Warren P. ; Christakis George T.,CAX ; Spence Paul ; Ward Thomas ; Allen Douglas P., Fastener delivery and deployment mechanism and method for placing the fastener in minimally invasive surgery.
Liotta Domingo S. (Calle 3 de Febrero 2025 Buenos Aires ARX) DeLiotta Holga E. T. (Calle 3 de Febrero 2025 Buenos Aires ARX), Frame support for cardiac tissue valves.
Rousseau Eduard P. M. (Maastricht NLX) van Steenhoven Antonius A. (Nuenen NLX) Janssen Joannes D. (Nuenen NLX) Wouters Leonardus H. G. (Weert NLX), Heart valve prosthesis, method for producing a heart valve prosthesis and mould applied thereby.
Rosen Jonathan J. (Fountain Valley CA) Acosta George M. (Long Beach CA) Bowman Christopher J. (Newport Beach CA), Heart valve with removable cusp protector band.
Adams Daniel O. (Orono MN) Wang Lixiao (St. Paul MN) Sogard David J. (Edina MN) Hendrickson Gary L. (New Hope MN), Imaging balloon catheter and methods for use and manufacture.
Donlon Brian S. ; Peters William S.,AUX ; Garrison Michi E. ; Rosenman Daniel C. ; Stevens John H.,GBX, Less-invasive devices and methods for cardiac valve surgery.
Ionescu Marian I. (Leeds CA GB2) Lenker Jay A. (Laguna Beach CA) Rosenbluth Robert F. (Laguna Niguel CA) Seiler ; Jr. Louis (Huntington Beach CA), Low profile prosthetic xenograft heart valve.
Warren P. Williamson, IV ; Paul A. Spence ; George T. Chistakis CA; Mark Ortiz, Means and method of replacing a heart valve in a minimally invasive manner.
Williamson ; IV Warren ; Spence Paul A. ; Christakis George T.,CAX ; Ward Thomas J. ; DiNovo Dominic P. ; Keller George A. ; Robinson Cecil R. ; VanHoose E. Dale, Means and method of replacing a heart valve in a minimally invasive manner.
Grooters Ronald K. (3300 Fuller Rd. West Des Moines IA 50265), Method of replacing a defective atrio-ventricular valve with a total atrio-ventricular valve bioprosthesis.
Colvin Stephen ; Grossi Eugene ; Katz Allan ; Oddo Paul, Passive knotless suture terminator for use in minimally invasive surgery and to facilitate standard tissue securing.
Love Charles S. (Camarillo CA) Love Jack W. (Santa Barbara CA) Calvin John H. (Carpenteria CA), Prefabricated sterile and disposable kits for the rapid assembly of a tissue heart valve.
Religa Zbigniew (Warsaw PLX) Stolarzewicz Bogdan (Katowice PLX) Cichon Romuald (Bytom PLX) Kryzskow Marek (Swietochlowice PLX) Stozek Jolanta (Katowice PLX), Process and apparatus for the production of a heart valve prosthesis.
Love Charles S. (Camarillo CA) Love Jack W. (Santa Barbara CA), Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure.
Love Charles S. (Camarillo CA) Love Jack W. (Santa Barbara CA) Calvin John H. (Carpenteria CA), Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment.
Love Charles S. (Camarillo CA) Love Jack W. (Santa Barbara CA) Calvin John H. (Carpenteria CA), Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment.
Love Charles S. (Camarillo CA) Love Jack W. (Santa Barbara CA) Calvin John H. (Carpenteria CA), Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment.
Ross Donald N. (25 Upper Wimpole St. London W.1 GB2) Bodnar Endre (9 West End Ct. ; West End Ave. Pinner ; Middlesex GB2) Hoskin William J. (5 Long Buftlers Harpenden ; Hertfordshire GB2), Stent for a cardiac valve.
Panescu Dorin ; Whayne James G. ; Swanson David K. ; McGee David ; TenHoff Harm, Systems and methods for visualizing interior tissue regions using expandable imaging structures.
Andersen, Henning Rud; Hasenkam, John Michael; Knudsen, Lars Lyhne, Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis.
Andersen, Henning Rud; Hasenkam, John Michael; Knudsen, Lars Lyhne, Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis.
Andersen Henning R. (Dalvangen 37A DK-8270 Hoejbjerg DKX) Hasenkam John M. (Aprilvej 8 DK-8210 Aarhus V DKX) Knudsen Lars L. (RudolfWulffsgade 6,4.mf. DK-8000 Aarhus C DKX), Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis.
Palmaz,Julio C.; Sprague,Eugene A.; Fuss,Cristina; Marton,Denes; Wiseman,Roger W.; Banas,Christopher E.; Boyle,Christopher T.; Bailey,Steven R., Valvular prostheses having metal or pseudometallic construction and methods of manufacture.
Williamson ; IV Warren P. ; Spence Paul A. ; Keller George A. ; Robinson Cecil R. ; Ward Thomas J., Wire fasteners for use in minimally invasive surgery and apparatus and methods for handling those fasteners.
Williamson ; IV Warren P. ; Spence Paul A. ; Keller George A. ; Robinson Cecil R. ; Ward Thomas J., Wire fasteners for use in minimally invasive surgery and means and methods for handling those fasteners.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.