Light-based spectroscopy with improved signal-to-noise ratio
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IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
G01J-003/00
A61B-005/00
A61B-005/1455
G01J-003/10
G01J-003/28
G06F-019/00
G16H-040/67
G01N-033/15
G01N-033/02
G01J-003/02
G01J-003/42
G01N-021/39
G01N-033/44
G01N-033/49
G01J-003/14
A61B-005/145
G01N-021/359
G01J-003/453
G01N-021/88
G01N-021/3563
H01S-003/30
G01N-021/35
G01J-003/12
H01S-003/00
H01S-003/067
G01N-021/95
G01N-021/85
G01J-003/18
G01M-003/38
출원번호
US-0015737
(2018-06-22)
등록번호
US-10172523
(2019-01-08)
발명자
/ 주소
Islam, Mohammed N.
출원인 / 주소
OMNI MEDSCI, INC.
대리인 / 주소
Brooks Kushman P.C.
인용정보
피인용 횟수 :
0인용 특허 :
163
초록▼
A measurement system includes a light source having semiconductor sources, a multiplexer, and one or more fused silica fibers configured to form an output optical beam having one or more optical wavelengths modulated at a modulation frequency. A light beam set-up includes a monochromator forming a f
A measurement system includes a light source having semiconductor sources, a multiplexer, and one or more fused silica fibers configured to form an output optical beam having one or more optical wavelengths modulated at a modulation frequency. A light beam set-up includes a monochromator forming a filtered optical beam. A measurement apparatus delivers the filtered optical beam to a sample. A receiver receives a spectroscopy output beam generated from the sample by the filtered optical beam. The receiver is configured to use a lock-in technique that detects the modulation frequency, and to generate first and second signals responsive to light received while the light source is off and on, respectively. The measurement system improves a signal-to-noise ratio of the spectroscopy output beam by differencing the first and second signals. The receiver processes the spectroscopy output beam using chemometrics or multivariate analysis to permit identification of materials within the sample.
대표청구항▼
1. A measurement system comprising: a light source configured to generate an output optical beam, comprising: a plurality of semiconductor sources configured to generate an input optical beam;a multiplexer configured to receive at least a portion of the input optical beam and to form an intermediate
1. A measurement system comprising: a light source configured to generate an output optical beam, comprising: a plurality of semiconductor sources configured to generate an input optical beam;a multiplexer configured to receive at least a portion of the input optical beam and to form an intermediate optical beam;one or more fibers configured to receive at least a portion of the intermediate optical beam and to form the output optical beam;wherein at least a portion of the one or more fibers comprises a fused silica fiber;wherein the output optical beam comprises one or more optical wavelengths; andwherein the output optical beam is modulated at a modulation frequency;a light beam set-up comprising a monochromator configured to receive at least a portion of the output optical beam and to form a filtered optical beam;a measurement apparatus configured to receive a received portion of the filtered optical beam and to deliver a delivered portion of the filtered optical beam to a sample; anda receiver configured to receive at least a portion of a spectroscopy output beam from the sample that is generated by the delivered portion of the filtered optical beam, wherein the receiver is further configured to use a lock-in technique that detects the modulation frequency, and wherein the receiver is further configured to: generate a first signal in response to light received while the light source is off; andgenerate a second signal in response to light received while the light source is on;wherein the measurement system is configured to improve a signal-to-noise ratio of the spectroscopy output beam by differencing the first signal and the second signal; andwherein the receiver is further configured to process the at least a portion of the spectroscopy output beam to generate an output signal, wherein the receiver processing includes at least in part using chemometrics or multivariate analysis to permit identification of materials within the sample; andwherein the output signal is based at least in part on a chemical composition of the sample. 2. The system of claim 1, wherein at least a portion of the one or more optical wavelengths is between 700 nanometers and 2500 nanometers, and wherein the light source comprises a super-continuum light source. 3. The system of claim 1, wherein the sample comprises plastics or food industry goods, and the measurement system is configured to be used for on-line process control. 4. The system of claim 1, wherein the light source is pulsed, and the receiver is further configured to perform time-gated detection and to be synchronized with one or more pulses from the light source. 5. A measurement system comprising: a light source configured to generate an output optical beam, comprising: a plurality of semiconductor sources configured to generate an input optical beam;a multiplexer configured to receive at least a portion of the input optical beam and to form an intermediate optical beam;one or more fibers configured to receive at least a portion of the intermediate optical beam and to form the output optical beam;wherein at least a portion of the one or more fibers comprises a fused silica fiber;wherein the output optical beam comprises one or more optical wavelengths; andwherein the output optical beam is modulated at a modulation frequency;a light beam set-up configured to receive at least a portion of the output optical beam and to form a filtered optical beam;a measurement apparatus configured to receive a received portion of the filtered optical beam and to deliver a delivered portion of the filtered optical beam to a sample; anda receiver configured to receive at least a portion of a spectroscopy output beam generated from the sample by the delivered portion of the filtered optical beam, wherein the receiver is further configured to use a lock-in technique that detects the modulation frequency, and wherein the receiver is further configured to: generate a first signal in response to light received while the light source is off; andgenerate a second signal in response to light received while the light source is on;wherein the measurement system is configured to improve a signal-to-noise ratio of the spectroscopy output beam by differencing the first signal and the second signal;wherein the receiver is further configured to process the at least a portion of the spectroscopy output beam to generate an output signal, wherein the receiver processing includes at least in part using chemometrics or multivariate analysis to permit identification of materials within the sample; andwherein the light source and the receiver are remote from the sample. 6. The system of claim 5, wherein the light source comprises a super-continuum light source. 7. The system of claim 5, wherein the measurement system is configured to be used for on-line process control, and the measurement system is configured to perform non-destructive quality control or constitutive analysis. 8. The system of claim 5, wherein at least a portion of the one or more optical wavelengths is between 700 nanometers and 2500 nanometers. 9. The system of claim 5, wherein the light beam set-up further comprises a monochromator to at least in part contribute to forming the filtered optical beam. 10. The system of claim 5, wherein the light beam set-up is further configured to separate the filtered optical beam into a reference arm and a sample arm, wherein at least a portion of the sample arm forms the delivered portion of the filtered optical beam, and wherein the reference arm is configured to be coupled to the light source, wherein the reference and sample arms are further coupled to the receiver, and wherein the receiver is further configured to use the reference arm to at least partially cancel out effects from fluctuations in the light source. 11. The system of claim 5, wherein the light source is pulsed, and the receiver is further configured to perform time-gated detection and to be synchronized with one or more pulses from the light source. 12. The system of claim 5, wherein the sample comprises plastics or food industry goods, and wherein the sample further comprises hydro-carbons, nitrogen or oxygen. 13. A measurement system comprising: a light source configured to generate an output optical beam, comprising: a plurality of semiconductor sources configured to generate an input optical beam;a multiplexer configured to receive at least a portion of the input optical beam and to form an intermediate optical beam;one or more fibers configured to receive at least a portion of the intermediate optical beam and to form the output optical beam;wherein at least a portion of the one or more fibers comprises a fused silica fiber;wherein the output optical beam comprises one or more optical wavelengths; andwherein the light source and output optical beam are pulsed;a light beam set-up configured to receive at least a portion of the output optical beam and to form a filtered optical beam;a measurement apparatus configured to receive a received portion of the filtered optical beam and to deliver a delivered portion of the filtered optical beam to a sample; anda receiver configured to receive at least a portion of a spectroscopy output beam generated from the sample by the delivered portion of the filtered optical beam, wherein the receiver is further configured to perform time-gated detection and to be synchronized with one or more pulses from the light source;wherein the receiver is further configured to process the at least a portion of the spectroscopy output beam to generate an output signal, wherein the receiver processing includes at least in part using chemometrics or multivariate analysis to permit identification of materials within the sample; andwherein the output signal is based at least in part on a chemical composition of the sample, and wherein the light source and receiver are remote from the sample. 14. The system of claim 13, wherein the output optical beam is modulated at a modulation frequency, and wherein the receiver is configured to use a lock-in technique that detects the modulation frequency. 15. The system of claim 14, wherein the receiver is further configured to perform band filtering at the modulation frequency, and wherein the modulation frequency has a phase, and wherein the receiver is configured to lock onto the phase. 16. The system of claim 15, wherein the receiver is further configured to: generate a first signal in response to light received while the light source is off; andgenerate a second signal in response to light received while the light source is on;wherein the measurement system is configured to improve a signal-to-noise ratio of the spectroscopy output beam by differencing the first signal and the second signal. 17. The system of claim 16, wherein the light beam set-up further comprises a monochromator to at least in part contribute to forming the filtered optical beam, wherein the light beam set-up is further configured to separate the filtered optical beam into a reference arm and a sample arm, wherein at least a portion of the sample arm forms the delivered portion of the filtered optical beam, and wherein the reference arm is configured to be coupled to the light source, wherein the reference and sample arms are further coupled to the receiver, and wherein the receiver is further configured to use the reference arm to at least partially cancel out effects from fluctuations in the light source. 18. The system of claim 17, wherein at least a portion of the one or more optical wavelengths is between 700 nanometers and 2500 nanometers. 19. The system of claim 18, wherein the measurement system is configured to be used for on-line process control, wherein the sample comprises plastics or food industry goods, and wherein the sample further comprises hydrocarbons, nitrogen or oxygen. 20. The system of claim 19, wherein the light source comprises a super-continuum light source.
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