$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Compositions and methods for the prevention and treatment of cancer

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-038/00
  • C07K-014/00
  • A61K-047/48
  • A61K-047/62
  • A61K-047/69
출원번호 US-0353602 (2016-11-16)
등록번호 US-10172955 (2019-01-08)
발명자 / 주소
  • Santamaria, Pedro
출원인 / 주소
  • UTI Limited Partnership
대리인 / 주소
    Wilson Sonsini Goodrich & Rosati
인용정보 피인용 횟수 : 0  인용 특허 : 45

초록

Conventional cancer immunotherapy falls short at efficiently expanding T cells that specifically target cancerous cells in numbers sufficient to significantly reduce the tumor size or cancerous cell number in vivo. To overcome this limitation, provided herein are nanoparticles coated with MHC class

대표청구항

1. A complex comprising: (a) a nanoparticle core having a diameter from about 1 nm to about 100 nm;(b) from 10 to 500 cancer or tumor-relevant antigen/CD1 protein complexes coupled to the nanoparticle core; and(c) a plurality of co-stimulatory molecule complexes coupled to the nanoparticle core;wher

이 특허에 인용된 특허 (45)

  1. Blattler Walter A. (Brookline MA) Lambert John M. (Brookline MA) Senter Peter D. (Jamaica Plain MA), Acid-cleavable compound, use in protein conjugates and drug delivery systems.
  2. Berenson, Ronald J; Law, Che; Bonyhadi, Mark; Saund, Zahbea; Craig, Stewart; Hardwick, Alan; Kalamasz, Dale; McMillen, David; Chana, Harjinder Singh, Activation and expansion of T cells.
  3. Wang Rong-Fu ; Rosenberg Steven A., Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein.
  4. Jansen Franz K. (Castries FRX) Gros Pierre (Montpellier FRX), Anti-cancer drugs for the treatment of melanomas and method for preparing thereof.
  5. Rodwell John D. (Yardley PA) McKearn Thomas J. (Narberth PA), Antibody conjugates for the delivery of compounds to target sites.
  6. Sundoro Boby M. (West Orange NJ), Bifunctional linker.
  7. Kent E. Coulter ; Thomas Mayer ; Roger W. Phillips ; John S. Matteucci, Bright metal flake based pigments.
  8. Van der Merwe Kirsten J. (Stellenbosch ZAX) Polson Alfred (Camps Bay ZAX), Carrier bound immunosorbent.
  9. Teron William (Rockcliffe CAX), Ceiling structure.
  10. Won, Jong Ok; Kang, Yong Soo; Jung, Bum Suk; Yoon, Yeo Sang, Composite polymers containing nanometer-sized metal particles and manufacturing method thereof.
  11. Santamaria, Pedro, Compositions and methods for the prevention and treatment of cancer.
  12. Hershberg,Robert M.; Hosken,Nancy Ann; Lodes,Michael J.; Mohamath,Raodoh, Compositions and methods for the therapy and diagnosis of inflammatory bowel disease.
  13. Nicolotti Robert A. (Furguson MO) Dean Richard T. (Chesterfield MO), Coupling agents for radiolabeled antibody fragments.
  14. Yatvin Milton B. (Portland OR) Stowell Michael H. B. (Pasadena CA) Gallicchio Vincent S. (Lexington KY) Meredith Michael J. (Lake Oswego OR), Covalent microparticle-drug conjugates for biological targeting.
  15. Yoshikawa Akira (Tokyo JPX), Decorative laminate and a manufacturing method therefor.
  16. Braun,Jonathan; Cohavy,Offer, Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens.
  17. Jiang, Shaoyi; Zhang, Zheng; Chen, Shengfu; Vaisocherova, Hana, Dual-functional nonfouling surfaces comprising target binding partner covalently coupled to polymer attached to substrate.
  18. Gordon Julian (Arlesheim CHX) Staehelin Theophil (Arlesheim CHX) Towbin Harry (Allschwil CHX), Electrophoretically transferring electropherograms to nitrocellulose sheets for immuno-assays.
  19. Hopp, Thomas P., Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity.
  20. Licalsi, Cynthia; Ward, Gary; Greenspan, Bernard; Witham, Clyde, Inhaled vaccines.
  21. Carter, Paul J.; Presta, Leonard G.; Ridgway, John B., Knobs and holes heteromeric polypeptides.
  22. Carter, Paul J.; Presta, Leonard G.; Ridgway, John B., Knobs and holes heteromeric polypeptides.
  23. Carter, Paul J.; Presta, Leonard G.; Ridgway, John B., Knobs and holes heteromeric polypeptides.
  24. Konigsberg Paula J. (Pasadena CA) Richer Leroy L. (San Gabriel CA) Schmidt Paul G. (San Marino CA) Uliana Joseph A. (Sierra Madres CA), Liposome targeting using receptor specific ligands.
  25. Klaveness Jo (Oslo NOX) Berg Arne (Sandvika NOX) Jacobsen Trond Vegard (Oslo NOX) Rongved Pal (Nesoddtangen NOX) Ege Thorfinn (Tranby NOX) Kikuchi Hiroshi (Tokyo JPX) Yachi Kiyoto (Tokyo JPX), Liposomes.
  26. Yamamuro Sigeaki (Zushi JPX) Abo Keiju (Yokosuka JPX) Tanaka Yoshikazu (Yokohama JPX) Kumura Haruyoshi (Yokohama JPX) Hirano Hiroyuki (Yokosuka JPX) Morimoto Yoshiro (Yokosuka JPX), Method and apparatus for controlling reduction ratio of continuously variable transmission with acceleration compensatio.
  27. Carter Paul J. ; Presta Leonard G. ; Ridgway John B., Method for making heteromultimeric polypeptides.
  28. Carter Paul J. ; Presta Leonard G. ; Ridgway John B., Method for making heteromultimeric polypeptides.
  29. Carter Paul J. ; Presta Leonard G. ; Ridgway John B., Method for making heteromultimeric polypeptides.
  30. Carter, Paul J.; Presta, Leonard G.; Ridgway, John B., Method for making heteromultimeric polypeptides.
  31. Lin,Hsing Kuang; Walsh,Daniel Edward, Method of producing gold nanoparticle.
  32. Franzen,Stefan; Feldheim,Daniel L.; Tkachenko,Alexander G.; Godek,Marisha L.; Ryan,Joseph A.; Franzen, legal representative,Stefan; Anderson,Miles F., Nanoparticle delivery vehicle.
  33. Nagy,Jon O.; Bargatze,Robert F.; Jutila,John W.; Cutler,Jim E.; Glee,Pati M., Nanoparticle vaccines.
  34. Turos, Edward; Shim, Jeung-Yeop, Nanoparticles for drug-delivery.
  35. Breton,Gary L., Nucleic acid sequences relating tofor diagnostics and therapeutics.
  36. Tetelman Bruce (Fort Lee NJ) Milios Yannis (New York NY) Park Il-Pyung (Palisades Park NJ) Recht Tom (Forest Hills NY), Point-of-sale terminal for laundry or dry cleaning establishments.
  37. DeLuca Patrick P. (Lexington KY) Kanke Motoko (Fukuyama JPX) Sato Toyomi (Tokyo CA JPX) Schroeder Hans G. (Encinitas CA), Porous microspheres for drug delivery and methods for making same.
  38. Pozarnsky, Gary A.; Fee, Michael J., Process for the manufacture of metal nanoparticle.
  39. Margel Shlomo,ILX ; Bamnolker Hanna,ILX, Process for the preparation of microspheres and microspheres made thereby.
  40. Platzek Johannes (Berlin DEX) Niedballa Ulrich (Berlin DEX) Radeuchel Bernd (Berlin DEX), Process for the production of DTPA-tetraesters of terminal carboxylic acids.
  41. Nayfeh, Munir H.; Therrien, Joel; Yamani, Zain H., Silicon nanoparticle and method for producing the same.
  42. Berenson, Ronald; Law, Che; Bonyhadi, Mark; Saund, Narinder; Craig, Stewart; Hardwick, Alan; Kalamasz, Dale; McMillen, David, Simultaneous stimulation and concentration of cells.
  43. Bunge, Scott D.; Boyle, Timothy J., Synthesis metal nanoparticle.
  44. Zhou,Bing; Parasher,Sukesh; Wu,Zhihua; Zhou,Zhenhua, Titanium dioxide nanoparticles and nanoparticle suspensions and methods of making the same.
  45. Shih Lisa B. (Cedar Grove NJ) Primus Frederick J. (Pittstown NJ) Goldenberg Milton D. (Short Hills NJ), Tumoricidal methotrexate-antibody conjugate.
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트