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Swallowable drug delivery device and methods of drug delivery

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61M-031/00
  • A61K-031/155
  • A61M-005/20
  • A61K-038/26
  • A61K-038/27
  • A61K-038/28
  • A61K-009/48
  • A61M-005/168
  • A61K-038/22
  • A61K-045/06
  • A61K-038/29
  • A61K-009/00
  • A61K-038/17
  • A61M-005/172
  • A61M-005/14
  • A61M-005/142
출원번호 US-0250937 (2016-08-30)
등록번호 US-10179228 (2019-01-15)
발명자 / 주소
  • Imran, Mir
출원인 / 주소
  • Rani Therapeutics, LLC
대리인 / 주소
    Wilson Sonsini Goodrich & Rosati
인용정보 피인용 횟수 : 1  인용 특허 : 76

초록

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device compri

대표청구항

1. An ingestible device suitable for swallowing into a lumen of a gastrointestinal tract of a patient, the lumen having a lumen wall, the device comprising: a capsule sized to pass through the intestinal tract;a preparation comprising a solid therapeutic agent comprising a protein or polypeptide dis

이 특허에 인용된 특허 (76)

  1. Kink, John A.; Worledge, Katherine L.; Stafford, Douglas C., Antibodies to cytokines in the prevention and treatment of inflammatory bowel disease.
  2. Marco, Doron; Eckhouse, Shimon, Bioerodible self-deployable intragastric implants.
  3. Heller Jorge (Palo Alto CA) Baker Richard W. (Bend OR), Bioerodible system for delivering drug manufactured from poly(carboxylic acid).
  4. Tanaka, Shinsuke; Kawano, Hironao; Takizawa, Hironobu, Body-insertable apparatus.
  5. Freyman, Toby, Catheter for endoluminal delivery of therapeutic agents that minimizes loss of therapeutic.
  6. Fabio Giannessi IT; Mauro Marzi IT; Patrizia Minetti IT; Francesco De Angelis IT; Maria Ornella Tinti IT; Piero Chiodi IT; Arduino Arduini IT, Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase.
  7. Berliner David L. ; Nacht Sergio, Delivery of drugs to the lower gastrointestinal tract.
  8. Wright Jeremy C. (Los Altos CA) Eckenhoff James B. (Los Altos CA) Maruyama Frederick H. (San Jose CA) Peery John R. (Stanford CA), Delivery system comprising means for controlling internal pressure.
  9. Lewkowicz,Shlomo; Gat,Daniel; Kraizer,Yehudit; Gilad,Zvika; Leuw,David; Meron,Gavriel; Glukhovsky,Arkady, Device and method for examining a body lumen.
  10. Hugemann Berhhard (Frankfurt am Main DEX) Schuster Otto (Bad Soden DEX), Device for the release of substances at defined locations in the alimentary tract.
  11. Pasricha Pankaj J. (Columbia MD) Kalloo Anthony N. (Glenndale MD), Device for treating gastrointestinal muscle disorders and other smooth muscle dysfunction.
  12. Imran, Mir, Device, system and methods for the oral delivery of therapeutic compounds.
  13. Imran, Mir A.; Herrmann, Peter; Syed, Baber; Williams, Timothy H.; Ong, Chang Jin; Method, Greg, Device, system and methods for the oral delivery of therapeutic compounds.
  14. Imran, Mir; Herrmann, Peter; Syed, Baber; Williams, Timothy H.; Ong, Chang Jin; Method, Greg, Device, system and methods for the oral delivery of therapeutic compounds.
  15. Prausnitz, Mark R.; Allen, Mark G.; Henry, Sebastien; McAllister, Devin V.; Ackley, Donald E.; Jackson, Thomas, Devices and methods for enhanced microneedle penetration of biological barriers.
  16. Yokoi,Takeshi; Takizawa,Hironobu; Segawa,Hidetake; Adachi,Hideyuki, Encapsulated medical device and method of examining, curing, and treating internal region of body cavity using encapsulated medical device.
  17. Imran, Mir, Energy harvesting mechanism.
  18. Darley,Derek Ian; McCusker,Desmond Andrew; Milojevic,Dusan; Parker,John, Feedthrough for electrical connectors.
  19. Ben Haim,Shlomo; Policker,Shai; Aviv,Ricardo; Glasberg,Ofer, Gastrointestinal methods and apparatus for use in treating disorders.
  20. Imran, Mir, GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  21. Schulman Joseph H. ; Canfield Lyle Dean, Hermetically sealed electrical feedthrough for use with implantable electronic devices.
  22. Lehmann Grard (Neuville de Poitou FRX) Metais Jol (Monts Sur Guesnes FRX) Meunier Jean-Francois (Noisy le Grand FRX) Gautier Jean-Philippe (Ozoir la Ferriere FRX), Implantable drug-dispensing capsule and system facilitating its use.
  23. Truex Buehl E. (Glendora CA) Gibson Scott R. (Granada Hills CA) Weinberg Alvin H. (Moorpark CA), Implantable medical device having shielded and filtered feedthrough assembly and methods for making such assembly.
  24. Houzego, Peter J.; Morgan, Peter N.; Hirst, Peter H.; Westland, Duncan J.; Wilding, Ian R., Ingestible device.
  25. Cantenys Jos (1501 Palzieux-Village CHX 1501), Intragastric balloon.
  26. Brister, Mark C.; Quintana, Nelson; Patel, Kaushik A.; Drake, Neil R.; Llevares, Antonio C.; Markovic, Dubravka; Rasdal, Andrew P.; VandenBerg, Amy D. L., Intragastric device.
  27. Leonard Robert J. (Lynnfield MA) Harman S. Mitchell (Ellicott City MD), Manufacture of partially fused peptide pellet.
  28. Yuda Shunichi (Hanishina JPX) Ito Hiroshi (Hanishina JPX) Tanaka Mamoru (Hanishina JPX), Medical capsule and apparatus for activating the same.
  29. Naimark, Wendy; Palasis, Maria; Herrmann, Robbert A, Medical device for delivery of a biologically active material to a lumen.
  30. Imran, Mir A., Method for delivering a therapeutic agent into the wall of the small intestine.
  31. Imran, Mir, Method for delivering exenatide to a patient in need thereof.
  32. Imran, Mir, Method for delivering gonadotropin releasing hormone into a lumen of the intestinal tract.
  33. Imran, Mir, Method for delivering liraglutide preparations into a lumen of the intestinal tract using a swallowable drug delivery device.
  34. Imran, Mir, Method for delivering pramlintide into a lumen of the intestinal tract using a swallowable drug delivery.
  35. Imran, Mir, Method for delivery of somatostatin into a lumen of the intestinal tract.
  36. Saffran Murray (Toledo OH) Neckers Douglas C. (Perrysburg OH), Method of use of polymers containing cross-linked azo bonds for releasing therapeutic agents into the lower gastrointest.
  37. Imran, Mir, Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device.
  38. Imran, Mir, Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device.
  39. Imran, Mir, Methods for delivering insulin preparations into a lumen of the intestinal tract using a swallowable drug delivery device.
  40. Imran, Mir, Methods for delivering insulin preparations into a lumen of the intestinal tract using a swallowable drug delivery device.
  41. Nicolaides Ernest D. (Ann Arbor MI) Tinney Francis J. (Ann Arbor MI) Kaltenbronn James S. (Ann Arbor MI) DeJohn Dana E. (Ann Arbor MI) Lunney Elizabeth A. (Ann Arbor MI) Roark W. Howard (Ann Arbor MI, Modified tripeptides.
  42. Rusin, Robert; Nowaczyk, Michael, One piece header assembly over molded to an implantable medical device.
  43. Lee Eun Soo ; Bura Scott A. ; Yum Su Il ; Wong Patrick S.-L. ; Theeuwes Felix, Osmotic drug delivery devices with hydrophobic wall materials.
  44. Eckenhoff ; deceased James B. ; Holladay Leslie A. ; Leonard ; Jr. John Joseph ; Leung Iris K. M. ; Tao Sally A. ; Magruder Judy A. ; Carr John P. ; Wright Jeremy, Peptide/protein suspending formulations.
  45. Nadler,Jerry L., Pharmaceutical compositions and methods for restoring β-cell mass and function.
  46. Kornfelt Troels (Virum DKX) Rasmussen Henrik (Copenhagen DKX) Jensen Flemming Steen (Alleroed DKX), Pharmaceutical preparation.
  47. Sosebee Thomas G. ; Chen Philip H. ; Gibson Dennis ; Ulmer Kenneth R., Semiconductor device packaging and method of fabrication.
  48. Imran, Mir, Skin penetrating device and method for subcutaneous solid drug delivery.
  49. Phillips, Jeffrey O., Substituted benzimidazole dosage forms and method of using same.
  50. Yoshioka Toshio (Hyogo JPX) Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Kyoto JPX), Sustained release microcapsule for water soluble drug.
  51. Imran, Mir A.; Hashim, Mir; Arnsdorf, Emily, Swallowable capsule and method for stimulating incretin production within the intestinal tract.
  52. Imran, Mir A.; Hashim, Mir; Arnsdorf, Emily, Swallowable capsule and method for stimulating incretin production within the intestinal tract.
  53. Imran, Mir A.; Hashim, Mir; Arnsdorf, Emily, Swallowable capsule and method for stimulating incretin production within the intestinal tract.
  54. Imran, Mir A.; Hashim, Mir; Arnsdorf, Emily, Swallowable capsule and method for stimulating incretin production within the intestinal tract.
  55. Imran, Mir; Hashim, Mir; Arnsdorf, Emily, Swallowable capsule and method for stimulating incretin production within the intestinal tract.
  56. Imran, Mir, Swallowable drug delivery device and method of delivery.
  57. Imran, Mir, Swallowable drug delivery device and method of delivery.
  58. Imran, Mir, Swallowable drug delivery device and methods of drug delivery.
  59. Imran, Mir, Swallowable drug delivery device and methods of drug delivery.
  60. Imran, Mir, Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  61. Imran, Mir, Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  62. Imran, Mir, Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  63. Imran, Mir, Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  64. Imran, Mir, Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  65. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  66. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  67. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  68. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  69. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  70. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  71. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  72. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  73. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  74. Imran, Mir, Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  75. Imran, Mir A., Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.
  76. Imran, Mir, Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device.

이 특허를 인용한 특허 (1)

  1. Imran, Mir, Therapeutic agent preparations into a lumen of the intestinal tract using a swallowable drug delivery device.
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