A device for enhancing the breathing efficiency of a patient is provided. The implantable device may include a deployed configuration with one or more helical sections with proximal end in a stand-off proximal end configuration. The stand-off proximal end configuration may reduce migration of the de
A device for enhancing the breathing efficiency of a patient is provided. The implantable device may include a deployed configuration with one or more helical sections with proximal end in a stand-off proximal end configuration. The stand-off proximal end configuration may reduce migration of the deployed device and may preserve implant tissue compression. Alternative configurations may include two or more helical sections with a transition section disposed between the two or more helical sections. A device may include a right-handed helical section and a left-handed helical section and the transition section comprises a switchback transition section. The switchback section may provide greater control of the device during deployment by limiting recoiling forces of a device comprising a spring material. The deployed device may compress the lung to increase a gas filling resistance of the compressed portion of the lung, and/or increase tension and elastic recoil in other portions of the lung.
대표청구항▼
1. A lung volume reduction system for enhancing a breathing efficiency of a patient with an airway, the system comprising: an implantable device having an elongate body including a proximal end and a distal end, the implantable device further having a first configuration and a second configuration,
1. A lung volume reduction system for enhancing a breathing efficiency of a patient with an airway, the system comprising: an implantable device having an elongate body including a proximal end and a distal end, the implantable device further having a first configuration and a second configuration, the second configuration of the implantable device corresponding to a configuration of the implantable device pre-implantation or post-implantation, the second configuration comprising at least one helical section;wherein the at least one helical section includes a proximal portion, a distal portion, and a helical axis, the proximal portion and the distal portion of the at least one helical section configured to compress lung tissue disposed between the proximal portion and the distal portion;wherein the elongate body transitions from the at least one helical section to a stand-off proximal tail at the proximal end of the elongate body, the stand-off proximal tail comprising a distal portion adjacent to and bending from the at least one helical section, a proximal portion, and a bend disposed between the distal portion and the proximal portion. 2. The lung volume reduction system of claim 1, wherein the distal portion of the stand-off proximal tail is straight. 3. The lung volume reduction system of claim 2, wherein the proximal portion of the stand-off proximal tail is straight. 4. The lung volume reduction system of claim 1, wherein the second configuration comprises at least two helical sections, each of the at least two helical sections including a proximal portion, a distal portion, and a helical axis. 5. The lung volume reduction system of claim 4, wherein the respective helical axes are different when the implantable device is in the second configuration. 6. The lung volume reduction system of claim 4, wherein an angle between the respective helical axes is between about 190 degrees and 230 degrees when the implantable device is in the second configuration. 7. The lung volume reduction system of claim 4, wherein the respective helical axes are the same when the implantable device is in the second configuration. 8. The lung volume reduction system of claim 4, wherein the implantable device is configured to impart a compression force on lung tissue of the patient. 9. The lung volume reduction system of claim 8, wherein the proximal portion and the distal portion of each of the at least two helical sections are configured to compress lung tissue disposed between the proximal portion and the distal portion of each respective helical section. 10. The lung volume reduction system of claim 4, wherein the stand-off proximal tail extends away from the proximal portion of the respective helical axis of the at least two helical sections when the implantable device is in the second configuration. 11. The lung volume reduction system of claim 4, wherein a transition section disposed between the at least two helical sections transitions between oppositely handed helical configurations. 12. The lung volume reduction system of claim 11, wherein the transition section is configured to reduce recoil forces during implantation of the implantable device. 13. The lung volume reduction system of claim 11, wherein the transition section is configured to reduce migration of the implantable device post-implantation. 14. The lung volume reduction system of claim 13, wherein the transition section is configured to maintain compression force on lung tissue of the patient. 15. The lung volume reduction system of claim 4, wherein the at least two helical sections each include at least one complete helix turn. 16. The lung volume reduction system of claim 4, wherein the at least two helical sections include the same number of complete helix turns. 17. The lung volume reduction system of claim 4, wherein the at least two helical sections include a different number of complete helix turns. 18. The lung volume reduction system of claim 1, wherein the at least one helical section comprises a circular, conical, or spherical helical section in the second configuration. 19. The lung volume reduction system of claim 1, wherein at least a portion of the implantable device is covered by a jacket, the jacket configured to increase the diameter of the implantable device and provide more area per unit force post-implantation. 20. A method of enhancing breathing efficiency of a patient with a lung having an airway, the method comprising: providing an implant, the implant having an elongate body including a proximal end and a distal end;advancing the implant distally through the airway toward a target site of the lung of the patient while the implant is in a delivery configuration;deploying the implant at the target site of the lung by transitioning the implant from the delivery configuration to a deployed configuration, the deployed configuration of the implant comprising at least one helical section;wherein the at least one helical section includes a proximal portion, a distal portion and a helical axis; and wherein the proximal portion and the distal portion of the at least one helical section are configured to compress lung tissue disposed between the proximal portion and the distal portion at the target site; andwherein the elongate body transitions from the at least one helical section to a stand-off proximal tail at the proximal end of the elongate body, the stand-off proximal tail comprising a distal portion adjacent to and bending from the at least one helical section, a proximal portion, and a bend disposed between the distal portion and the proximal portion.
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