Light-emitting device and method for providing phototherapy to the brain
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61N-005/06
A61B-018/00
A61B-018/22
A61N-005/00
A61N-005/067
A61B-090/00
출원번호
US-0496571
(2009-07-01)
등록번호
US-10188872
(2019-01-29)
발명자
/ 주소
De Taboada, Luis
Streeter, Jackson
출원인 / 주소
Pthera LLC
대리인 / 주소
Fish & Richardson P.C.
인용정보
피인용 횟수 :
0인용 특허 :
234
초록▼
An apparatus is provided for irradiating at least a portion of a patient's brain with electromagnetic radiation to treat stroke, Parkinson's Disease, Alzheimer's Disease, or depression. The apparatus includes a source of the electromagnetic radiation. The apparatus further includes an output optical
An apparatus is provided for irradiating at least a portion of a patient's brain with electromagnetic radiation to treat stroke, Parkinson's Disease, Alzheimer's Disease, or depression. The apparatus includes a source of the electromagnetic radiation. The apparatus further includes an output optical element including a rigid and substantially thermally conductive material and a surface configured to be in thermal communication with the patient's body. The apparatus further includes a cooler thermally coupled to the output optical element to remove heat from the output optical element. The apparatus further includes a heat sink thermally coupled to the cooler, wherein the heat sink is positioned so that the electromagnetic radiation from the source propagates through the heat sink and through the output optical element.
대표청구항▼
1. An apparatus for irradiating at least a portion of a patient's brain with electromagnetic radiation to treat stroke, Parkinson's disease, Alzheimer's disease, or depression, the apparatus comprising: a source of the electromagnetic radiation;an output optical element comprising a rigid and substa
1. An apparatus for irradiating at least a portion of a patient's brain with electromagnetic radiation to treat stroke, Parkinson's disease, Alzheimer's disease, or depression, the apparatus comprising: a source of the electromagnetic radiation;an output optical element comprising a rigid and substantially thermally conductive material, the output optical element comprising a first surface configured to face towards the patient's scalp and to be in thermal communication with the patient's scalp during treatment and a second surface configured to face away from the patient's scalp during treatment;a cooler thermally coupled to the second surface of the output optical element to remove heat from the output optical element through the second surface; anda heat sink thermally coupled to the cooler, wherein the heat sink is positioned so that the electromagnetic radiation from the source propagates through the heat sink and through the output optical element. 2. The apparatus of claim 1, wherein the electromagnetic radiation has at least one wavelength in a range between about 780 nanometers and about 840 nanometers. 3. The apparatus of claim 1, wherein the rigid and substantially thermally conductive material comprises sapphire. 4. The apparatus of claim 1, wherein the apparatus is to actively cool an irradiated portion of the patient's scalp. 5. The apparatus of claim 1, further comprising an optical diffuser. 6. The apparatus of claim 5, wherein the output optical element comprises a lens and the optical diffuser. 7. The apparatus of claim 5, wherein the optical diffuser is optically coupled to the output optical element, and the electromagnetic radiation propagates through the optical diffuser prior to reaching the output optical element. 8. The apparatus of claim 1, wherein the cooler comprises a thermoelectric cooler. 9. The apparatus of claim 1, wherein the heat sink comprises a first portion and a second portion, the heat sink positioned so that the electromagnetic radiation is transmitted into the first portion, out of the second portion, and to the output optical element. 10. The apparatus of claim 9, wherein the heat sink further comprises a reflective inner surface between the first portion and the second portion, wherein the electromagnetic radiation propagates through a region bounded by the inner surface prior to reaching the output optical element. 11. The apparatus of claim 1, wherein the apparatus comprises at least one trigger switch, the trigger switch electrically coupled to the source, the trigger switch actuated by pressing the output optical element against a surface, the source responsive to the trigger switch by emitting light only when the trigger switch is actuated. 12. The apparatus of claim 1, wherein the apparatus is configured to be held in position by hand and sequentially moved to irradiate selected portions of the patient's body. 13. The apparatus of claim 1, wherein the output optical element is sufficiently thermally conductive to conduct heat from the patient's scalp at a sufficient rate to prevent, minimize, or reduce damage or discomfort to the patient from heating of the skin due to the irradiation. 14. An apparatus for irradiating at least a portion of a patient's brain with electromagnetic radiation to treat stroke, Parkinson's disease, Alzheimer's disease, or depression, the apparatus comprising: a source of the electromagnetic radiation, the electromagnetic radiation having at least one wavelength in a range between about 780 nanometers and about 840 nanometers;an output optical element comprising sapphire, the output optical element comprising a front surface configured to face towards the patient's scalp and to be in thermal communication with the patient's scalp during treatment and a back surface configured to face away from the patient's scalp during treatment;a thermoelectric cooler thermally coupled to the back surface of the output optical element and configured to remove heat from the output optical element through the back surface and to actively cool an irradiated portion of the patient's scalp; anda heat sink thermally coupled to the thermoelectric cooler, wherein the heat sink is positioned so that the electromagnetic radiation from the source propagates through the heat sink and through the output optical element.
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