A device (100) for delivering a medicament into a patient's body by injection into or through the patient's skin, including a main body having a top enclosure (116) and a bottom enclosure (104), a reservoir (160) disposed within the main body for containing the medicament, and an injection needle (1
A device (100) for delivering a medicament into a patient's body by injection into or through the patient's skin, including a main body having a top enclosure (116) and a bottom enclosure (104), a reservoir (160) disposed within the main body for containing the medicament, and an injection needle (152) for penetrating the skin of the patient, the needle (152) having a lumen and selectively communicating with the reservoir (160). The device also includes a pressurizing system (600, 140) for selectively pressurizing the reservoir (160). In a pre-activated position, the pressurizing system (600, 140) contacts and compresses the reservoir (160) to reduce the initial volume of the reservoir (160), thereby allowing for partial filling of the reservoir (160).
대표청구항▼
1. A drug delivery device, comprising: a body including a top enclosure and a bottom enclosure;a reservoir disposed within the body for containing a medicament, the reservoir having a rigid portion and a movable portion;an injection needle for penetrating the skin of the patient, the needle having a
1. A drug delivery device, comprising: a body including a top enclosure and a bottom enclosure;a reservoir disposed within the body for containing a medicament, the reservoir having a rigid portion and a movable portion;an injection needle for penetrating the skin of the patient, the needle having a lumen and selectively communicating with the reservoir; anda pressurizing system for selectively pressurizing the reservoir, wherein the pressurizing system comprises: a plunger movable within the body, the plunger comprising at least one tab extending from an outer edge thereof; anda pressurization spring compressed by the plunger when the pressurizing system is in a pre-activated position;wherein in the pre-activated position, the pressurizing system contacts and compresses the movable portion of the reservoir to reduce a finable volume of the reservoir substantially to a predetermined dosage volume;wherein an immobile retaining portion of the body selectively retains the at least one tab to retain the pressurizing system in the pre-activated position against the force of the pressurization spring; andwherein the body includes at least one recessed channel to guide the at least one tab during plunger movement. 2. The device according to claim 1, wherein: the body comprises a cylindrical housing; andthe pressurizing system is disposed within the cylindrical housing. 3. A drug delivery device, comprising: a body including a top enclosure and a bottom enclosure, the bottom enclosure comprising a housing;a reservoir disposed within the body for containing a medicament;an injection needle for penetrating the skin of the patient, the needle having a lumen and selectively communicating with the reservoir; anda pressurizing system for selectively pressurizing the reservoir, wherein in a pre-activated position, the pressurizing system contacts and compresses the reservoir to reduce a finable volume of the reservoir;wherein the pressurizing system comprises; a plunger movable within the housing; anda pressurization spring compressed by the plunger when the pressurizing system is in the pre-activated position;wherein the plunger comprises at least one tab extending from an outer edge thereof;wherein the housing includes at least one recessed channel to guide the at least one plunger tab during plunger movement;wherein the at least one plunger tab comprises a leg extending from the outer edge of the plunger, and a foot extending from the leg;wherein the at least one recessed channel includes a retaining portion; andwherein a resistance between the foot and the retaining portion retains the pressurizing system in the pre-activated position against the force of the pressurization spring. 4. The device according to claim 3, wherein a length of the leg determines an amount of reduction of the fillable volume of the reservoir. 5. The device according to claim 4, wherein: the reservoir comprises a dome and a flexible reservoir dome seal;when the pressurizing system is in the pre-activated position a surface of the plunger contacts and compresses the reservoir dome seal to reduce the fillable volume of the reservoir; anda shape of the surface of the plunger that contacts the reservoir dome seal corresponds to a shape of the dome. 6. The device according to claim 5, further comprising an activator button movably disposed on the main body and movable from a pre-activated position to an activated position; wherein moving the activator button from the pre-activated position to the activated position causes rotation of the plunger such that the foot is free of the retaining portion and the plunger moves within the cylindrical housing due to the force of the pressurization spring, to pressurize the reservoir. 7. A drug delivery device, comprising: a body including a top enclosure and a bottom enclosure, the bottom enclosure comprising a housing;a reservoir disposed within the body for containing a medicament;an injection needle for penetrating the skin of the patient, the needle having a lumen and selectively communicating with the reservoir; anda pressurizing system for selectively pressurizing the reservoir, wherein in a pre-activated position, the pressurizing system contacts and compresses the reservoir to reduce a fillable volume of the reservoir;wherein the pressurizing system comprises; a plunger movable within the housing;a pressurization spring compressed by the plunger when the pressurizing system is in the pre-activated position;a retention plate disposed on the bottom enclosure; anda post disposed substantially at a center of the housing on one of the retention plate and the plunger, the post having a sprocket disposed at a distal end thereof;wherein the pressurization spring is disposed between the retention plate and the plunger;wherein the remaining one of the retention plate and the plunger includes an opening with a shape corresponding to the sprocket, the opening having slots interposed between fingers of remaining one of the retention plate and the plunger; andwherein in the pre activated position, teeth of the sprocket align with said fingers to maintain the pressurization spring compression. 8. The device according to claim 7, wherein the post and the one of the retention plate and the plunger where the post is disposed are integrally formed as a unitary structure. 9. The device according to claim 7, wherein: the plunger comprises at least one tab extending from an outer edge thereof; andthe cylindrical housing includes at least one recessed channel to guide the at least one plunger tab during plunger movement. 10. The device according to claim 7, wherein a length of the post determines an amount of reduction of the fillable volume of the reservoir. 11. The device according to claim 10, wherein: the reservoir comprises a dome and a flexible reservoir dome seal;when the pressurizing system is in the pre-activated position a surface of the plunger contacts and compresses the reservoir dome seal to reduce the initial volume of the reservoir; anda shape of the surface of the plunger that contacts the reservoir dome seal corresponds to a shape of the dome. 12. The device according to claim 11, further comprising an activator button movably disposed on the main body and movable from a pre-activated position to an activated position; wherein moving the activator button from the pre-activated position to the activated position causes rotation of one of the retention plate and the plunger with respect to the non-rotating one of the retention plate and the plunger such that the sprocket teeth align with the slots of the opening to release the plunger to move within the cylindrical housing under the force of the pressurization spring to pressurize the reservoir. 13. The device according to claim 12, wherein the post is disposed on the retention plate. 14. The device according to claim 12, wherein the post is disposed on the plunger. 15. The device according to claim 12, wherein moving the activator button from the pre-activated position to the activated position causes rotation of the retention plate to align the sprocket teeth with the slots of the opening. 16. The device according to claim 12, wherein moving the activator button from the pre-activated position to the activated position causes rotation of the plunger to align the sprocket teeth with the slots of the opening. 17. A drug delivery device, comprising: a body including a top enclosure and a bottom enclosure;a reservoir disposed within the body for containing a medicament;an injection needle for penetrating the skin of the patient, the needle having a lumen and selectively communicating with the reservoir; anda pressurizing system for selectively pressurizing the reservoir, wherein in a pre-activated position, the pressurizing system contacts and compresses the reservoir to reduce a fillable volume of the reservoir;wherein the bottom enclosure comprises a cylindrical housing;wherein the pressurizing system is disposed within the cylindrical housing and comprises; a plunger movable within the cylindrical housing; anda pressurization spring compressed by the plunger when the pressurizing system is in the pre-activated position;wherein the plunger comprises at least one tab extending from an outer edge thereof;wherein the cylindrical housing includes at least one recessed channel to guide the at least one plunger tab during plunger movement;wherein the at least one plunger tab comprises a leg extending from the outer edge of the plunger, and a foot extending from the leg;wherein the at least one recessed channel includes a retaining portion; andwherein a resistance between the foot and the retaining portion retains the pressurizing system in the pre-activated position against the force of the pressurization spring.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (120)
Crocker, Peter John, Apparatus for delivering a substance having one or more needles driven at high velocity.
Takeshita Ryuzo (No. 5-4-11 Koenji Minami ; Suginami-Ku,Tokyo JPX), Apparatus for injecting a desired volume of liquid in liquid and gas-liquid chromatography.
Prausnitz, Mark R.; Allen, Mark G.; Henry, Sebastien; McAllister, Devin V.; Ackley, Donald E.; Jackson, Thomas, Devices and methods for enhanced microneedle penetration of biological barriers.
Cabiri, Oz; Katz, David; Rozanowich, Mario; Danon, Haim; Gross, Joseph; Tsals, Izrail; Brodeur, Craig; Etheredge, Robert, Drug delivery device having improved adhesion and attachment system for drug delivery device.
Kriesel Marshall S. (Saint Paul MN) Kazemzadeh Farhad (Bloomington MN) Kriesel Matthew (St. Paul MN) Feng William (Lafayette CA) Barber Steve C. (Shorewood MN) Kluck William J. (Hudson WI), Fluid delivery apparatus and method of making same.
Kriesel Marshall S. (St. Paul MN) Arnold Steven M. (Minnetonka MN) Garrison James M. (South Minneapolis MN) Kazemzadeh Farhad (Bloomington MN) Kluck William J. (Hudson WI) Barber Steven C. (Shorewood, Fluid delivery apparatus and method of making same.
Kriesel Marshall S. ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W. ; Barber Steve C. ; Kluck William J., Fluid delivery device with bolus injection site.
Kriesel Marshall S. ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W. ; Barber Steve C. ; Kluck William J., Fluid delivery device with bolus injection site.
Kriesel Marshall S. ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W. ; Barber Steve C. ; Kluck William J., Fluid delivery device with bolus injection site.
Kriesel Marshall S. ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W. ; Barber Steve C. ; Kluck William J., Fluid delivery device with conformable ullage.
Kriesel Marshall S. ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W.. ; Barber Steve C. ; Kluck William J., Fluid delivery device with conformable ullage.
Kriesel Marshall S ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W ; Thompson Thomas N, Fluid delivery device with conformable ullage and fill assembly.
Kriesel Marshall S. ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W. ; Thompson Thomas, Fluid delivery device with conformable ullage and fill assembly.
Kriesel Marshall S ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Barber Steven C. ; Kluck William J. ; Feng William W., Fluid delivery device with fill adapter.
Kriesel Marshall S. ; Kazemzadeh Farhad ; Kriesel Matthew B. ; Feng William W. ; Barber Steve C. ; Kluck William J., Fluid delivery device with flow indicator and rate control.
Moberg, Sheldon B.; Hanson, Ian B.; Bente, IV, Paul F.; Tieck, Ruth Marie; Kavazov, Julian D.; Mounce, R. Paul, Infusion medium delivery device and method with drive device for driving plunger in reservoir.
Magruder Judy A. ; Eckenhoff ; deceased James B. ; Cortese Richard ; Wright Jeremy C. ; Peery John R. ; Bourneuf Edward V. ; Pike James B. ; Robinson Urano A. ; Sharockman John M. ; Smith Jonathan P., Interlocking couplings for osmotic delivery devices.
Delmore, Michael D.; Fleming, Patrick R.; Huntley, Douglas A.; Keister, Jamieson C.; Thomas, Cristina U.; Ferber, Richard H., Microneedle arrays and methods of manufacturing the same.
Shermer, Charles D.; Powell, Kenneth G.; Lastovich, Alexander G.; Kinsey, P. Spencer; Smutney, Chad C.; Polidoro, John M.; Browka, Ed; Sahi, Carl R.; Fentress, James K.; Chapin, David S.; Stipe, Daniel; Moss, Jeff M.; Kuroda, Melody, Patch-like infusion device.
Sullivan, Vincent J.; Jiang, Ge; Ferriter, Matthew S.; Powell, Kenneth G.; Kinsey, P. Spencer; Sahi, Carl R.; Polidoro, John M., Reconstituting infusion device.
Kriesel Marshall S. (St. Paul MN) Kazemzadeh Farhad (Bloomington MN) Kriesel Matthew B. (St. Paul MN) Feng William W. (Lafayette CA) Barber Steve C. (Shorewood MN) Kluck William J. (Hudson WI), Subdermal delivery device.
Lee Hai Bang (Taejeon KRX) Shin Bung Chul (Taejeon KRX), Transdermal administration method of protein or peptide drug and its administration device thereof.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.