[특허]Implantable medical device having enhanced endothelial migration features and methods of making the same

Vactronix Scientific, LLC

Implantable medical device having enhanced endothelial migration features and methods of making the same

국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-002/91 A61F-002/00 A61F-002/90 A61F-002/86 A61F-002/82 A61F-002/01 A61F-002/06 A61F-002/24
출원번호	US-0263029 (2016-09-12)
등록번호	US-10206772 (2019-02-19)
발명자 / 주소	Palmaz, Julio C.
출원인 / 주소	Vactronix Scientific, LLC
대리인 / 주소	Rosenbaum, David G.
인용정보	피인용 횟수 : 0 인용 특허 : 64

초록 ▼

An implantable medical device having enhanced endothelial migration features, generally comprises: a structural member including a leading edge and a trailing edge interconnected by a third surface region, the leading edge including a second surface region in a generally curvilinear cross-section, and the trailing edge including a fourth surface region in a generally curvilinear cross-section, whereby blood flow over the second surface region generate shear stress at the second surface region without an eddy region in the second surface region.

대표청구항 ▼

1. An implantable endoluminal stent, comprising: a plurality of structural members, each of the plurality of structural members having an irregular polygonal transverse cross-sectional profile and defined by a plurality of surface facets, some of the plurality of surface facets defining a luminal surface and some of the plurality of surface facets defining an abluminal surface of the endoluminal stent; andwherein the plurality surface facets defining the luminal surface of the endoluminal stent further comprise a concave curvilinear first surface facet having a second end projecting toward a luminal center, a concave curvilinear second surface facet having a first end projecting toward a luminal center and a planar third surface facet intermediate between and joining the first surface facet second end and the second surface facet first end. 2. The implantable endoluminal stent of claim 1, wherein the shear stress generated at the first surface facet is between about 5 and 25 dynes/cm2. 3. The implantable endoluminal stent of claim 1, wherein the first surface facet and second surface facet each further includes a radius of curvature Rs, wherein Rs is between about 1 nm to about 75 mm. 4. The implantable endoluminal stent of claim 3, wherein each of the first surface facet and the second surface facet join an abluminal surface to form an angle As, wherein the angle As is less than 90 degrees. 5. The implantable endoluminal stent of claim 4, wherein each of the first surface and the second surface facet join the third surface facet at an angle At, wherein the angle At is greater than 90 degrees. 6. The implantable endoluminal stent of claim 5, wherein a length of the third surface facet is less than a length of each of the first facet surface and the second facet surface. 7. The implantable endoluminal stent of claim 6, wherein the abluminal surfaces further comprise a first abluminal surface joining a second abluminal surface and the second abluminal surface joining a third abluminal surface, whereby the third abluminal surface joins the one of the plurality of surface facets on the luminal surface of the endoluminal stent thereby defining a substantially irregular hexagonal cross-section configuration of the structural member. 8. The implantable endoluminal stent of claim 7, wherein the length of the third surface facet is less than a length of the second surface facet. 9. The implantable endoluminal stent of claim 8, wherein the the first surface facet and the second surface facet include a plurality of geometric physiologically functional features including a focal adhesion point for affinity binding of endothelial cells. 10. The implantable endoluminal stent of claim 8, having at least one groove on the first surface facet, second surface facet, or third surface facet, wherein the at least one groove is between 7 to 20 μm wide.

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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

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연합인증

Implantable medical device having enhanced endothelial migration features and methods of making the same

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Implantable medical device having enhanced endothelial migration features and methods of making the same

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연구과제 타임라인

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