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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0883134 (2018-01-30) |
등록번호 | US-10213384 (2019-02-26) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 0 인용 특허 : 622 |
The present invention teaches a foamable pharmaceutical and cosmetic compositions comprising an aprotic polar solvent; foam compositions and uses thereof.
1. A non-aqueous composition formulated for skin delivery of an active agent comprising: a minocycline in a therapeutically effective amount of about 1% to about 5% by weight of the composition;a short chain alcohol comprising ethanol present in an amount of at least 55% by weight of the composition
1. A non-aqueous composition formulated for skin delivery of an active agent comprising: a minocycline in a therapeutically effective amount of about 1% to about 5% by weight of the composition;a short chain alcohol comprising ethanol present in an amount of at least 55% by weight of the composition;about 12% to about 50% by weight of the composition of a protic polar solvent comprising propylene glycol;a polymeric agent comprising a cellulose ether, wherein the cellulose ether is a hydroxypropyl cellulose present in an amount ranging from about 0.5% to about 1% by weight of the composition;a modulating agent comprising an antioxidizing agent present in an amount ranging from about 0.1% to about 10% by weight of the composition;a metal; andan essential oil,wherein the composition is surfactant free, non-aqueous, and free or essentially free of fatty alcohol. 2. The non-aqueous composition according to claim 1, wherein the minocycline is dissolved in the composition. 3. The non-aqueous composition according to claim 2, wherein the minocycline is a minocycline hydrochloride. 4. The non-aqueous composition according to claim 1, wherein the protic polar solvent is about 12% to about 30% by weight of the composition.
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