A cartridge device is provided for applying a fiber matrix to a tubular member such as a saphenous vein graft. The cartridge includes a housing, a tubular member holder, a rotational drive, and a polymer delivery assembly. The housing defines a chamber which surrounds the tubular member holder. The
A cartridge device is provided for applying a fiber matrix to a tubular member such as a saphenous vein graft. The cartridge includes a housing, a tubular member holder, a rotational drive, and a polymer delivery assembly. The housing defines a chamber which surrounds the tubular member holder. The rotational drive rotates the tubular member during the fiber application process.
대표청구항▼
1. A cartridge device for applying a fiber matrix to a tubular member, the cartridge device comprising: a housing that defines a chamber and comprises an attachment port;a tubular member holder positioned within the chamber;a rotation element operably connected to the tubular member holder;a polymer
1. A cartridge device for applying a fiber matrix to a tubular member, the cartridge device comprising: a housing that defines a chamber and comprises an attachment port;a tubular member holder positioned within the chamber;a rotation element operably connected to the tubular member holder;a polymer delivery assembly configured to deliver the fiber matrix comprising at least one polymer onto the tubular member;an inlet port; andan outlet port,wherein the attachment port is configured to (i) fluidly attach to a polymer reservoir comprising the at least one polymer and (ii) provide the at least one polymer to the polymer delivery assembly, and wherein at least one of the inlet port or the outlet port comprises a filtered port. 2. The device according to claim 1, wherein the inlet port, the outlet port, or a combination thereof comprises a membrane, wherein the membrane covers an opening of the inlet port, the outlet port, or the combination thereof. 3. The device according to claim 2, wherein the membrane is removably attached to the opening of the inlet port, the outlet port, or the combination thereof. 4. The device according to claim 2, wherein the membrane is configured to be punctured to uncover the opening of the inlet port, the outlet port, or the combination thereof. 5. The device according to claim 2, wherein the membrane comprises a resealable membrane. 6. The device according to claim 1, wherein the filtered port is configured to maintain sterility of the tubular member holder. 7. The device according to claim 1, wherein the filtered port is configured to provide ventilation of the housing. 8. The device according to claim 1, wherein the filtered port comprises a 0.2 micron filter. 9. The device according to claim 1, wherein the housing comprises a first portion, a mating second portion, and a seal therebetween. 10. The device according to claim 9, wherein the seal comprises a sterility barrier. 11. The device according to claim 1, wherein the polymer delivery assembly is configured to deliver a solvent, and wherein the device is configured to control a partial pressure of the solvent. 12. The device according to claim 11, wherein at least one of the inlet port or the outlet port attaches to an external environmental control device. 13. The device according to claim 12, wherein the external environmental control device is selected from the group consisting of: a positive pressure source; a vacuum source; a heating unit; a cooling unit; a humidifier; a dehumidifier; an ionizing unit; and any combination thereof. 14. The device according to claim 1, wherein the inlet port provides an inert gas to the device and controls one or more of: an ambient pressure, a humidity, or a combination thereof within the device. 15. The device according to claim 14, wherein the inert gas comprises nitrogen. 16. The device according to claim 1, wherein the polymer delivery assembly further comprises a nozzle configured to deliver the fiber matrix onto the tubular member. 17. The device according to claim 16, wherein the nozzle is positioned at a top of the housing or at a bottom of the housing. 18. The device according to claim 16, wherein the nozzle moves in a manner selected from the group consisting of: translation; oscillation; rotation; and any combination thereof. 19. The device according to claim 1, wherein the tubular member comprises a harvested tissue. 20. The device according to claim 19, wherein the tubular member comprises the harvested tissue selected from the group consisting of: a vein; an artery; a lymphatic duct; a vas deferens; a tear duct; an intestine; an esophagus; a ureter; a urethra; a trachea; a bronchi; a duct tissue; an Eustachian tube; a fallopian tube; and any combination thereof.
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