Method of laminating absorbable semi-crystalline polymeric films
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B32B-037/10
A61L-031/04
A61L-031/10
A61L-031/14
B29C-047/00
B29C-055/30
B32B-005/02
B32B-027/12
B32B-037/06
B32B-027/00
B32B-037/15
A61K-009/70
B29C-047/92
A61F-002/00
B29L-031/00
B32B-037/00
출원번호
US-0267700
(2016-09-16)
등록번호
US-10245817
(2019-04-02)
발명자
/ 주소
Andjelic, Sasa
Egidio, Dominick
출원인 / 주소
Ethicon, Inc.
대리인 / 주소
Crichton, David E.
인용정보
피인용 횟수 :
0인용 특허 :
16
초록▼
The invention relates to novel processes for the lamination of semi-crystalline, high-melting point, low glass transition polymeric films, which are extruded and subsequently laminated on various thermally sensitive substrates to form laminated medical device constructs in a specific time interval t
The invention relates to novel processes for the lamination of semi-crystalline, high-melting point, low glass transition polymeric films, which are extruded and subsequently laminated on various thermally sensitive substrates to form laminated medical device constructs in a specific time interval to allow low processing temperatures to avoid polymer film and/or substrate degradation or heat-related distortions. Also disclosed are laminated medical device constructs made from such processes.
대표청구항▼
1. A method of making a laminated medical device construct, comprising: a) extruding a polymer film having a semi-crystalline structure and a melting point temperature of 140° or higher, a glass transition temperature below 25° C., and a crystallinity, said polymer film being crystallizable at room/
1. A method of making a laminated medical device construct, comprising: a) extruding a polymer film having a semi-crystalline structure and a melting point temperature of 140° or higher, a glass transition temperature below 25° C., and a crystallinity, said polymer film being crystallizable at room/ambient conditions;b) laminating the polymer film directly to a substrate, said substrate being thermally sensitive and polymeric, to form the laminated medical device construct by conducting a thermal/pressure laminating step within about 10 minutes after the polymer film has been extruded wherein the polymer film has a crystallinity of about 10% or less in order to laminate said polymer film onto a substrate at a temperature of about 120° C. or lower, wherein the substrate is not damaged and the polymer film is effectively laminated to the substrate. 2. The method of claim 1, wherein the substrate is selected from the group consisting of non-woven substrate, woven substrate and mesh substrate. 3. The method of claim 1 wherein the polymer film comprises a polymer material selected from the group consisting of copolymers of lactide or glycolide as major components with one or more other components including caprolactone, poly (p-dioxanone); trimethylene carbonate (TMC), polyethylene glycol, and polyether ester formulations. 4. The method of claim 1, wherein the polymer film comprises a polymer material selected from the group consisting of polypropylene, polyethylene, polyethylene terephthalate, and Nylon. 5. The method of claim 1, wherein the polymer film comprises a copolymer of glycolide and epsilon-caprolactone in the molar ratio of about 75 to about 25%, respectively. 6. The method of claim 1, wherein the substrate comprises a material selected from the group consisting of collagen, calcium alginate, chitin, polyester, polypropylene, polysaccharides, polyacrylic acids, polymethacrylic acids, polyamines, polyimines, polyamides, polyesters, polyethers, polynucleotides, polynucleic acids, polypeptides, proteins, poly (alkylene oxide), polyalkylenes, polythioesters, polythioethers, polyvinyls, polymers comprising lipids, oxidized regenerated cellulose, and mixtures thereof. 7. The method of claim 1, wherein the lamination is performed off-line. 8. The method of claim 1, wherein the lamination is performed in-line reel-to-reel. 9. The method of claim 5, wherein the polymer film has a crystallinity that changes from about 0 to about 10% in the first 30 minutes after extrusion, and above 20% for a dwell/aging time longer than 24 hours. 10. The method of claim 1, wherein the extruded film is rolled and cut into pieces prior to lamination to the substrate.
Erneta, Modesto; Jamiolkowski, Dennis D.; Zhou, Jianguo Jack; Andjelic, Sasa, Copolymers of epsilon-caprolactone and glycolide for melt blown nonwoven applications.
Ikeda, Tsuyoshi; Koide, Koshi; Koike, Nobuyuki; Kawabata, Tadashi; Hirokane, Takeshi; Kuwahara, Shojiro, Polyester film, process for producing the same and use thereof.
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