초록

○ 연구결과
- 재배기술 확립 및 대량 생산 진행중
- 특허 출원 및 등록(출원 3건, 등록 1건)
- 논문발표 및 심포지엄 참여 2건 / 박람회 기술 및 제품전시 4건
- 사업성과 언론홍보 (방송5건, 신문잡지 50건)
- 제품개발 완료 및 수출, 판매중 (건조버섯, 추출 가공제품)

Abstract ▼

Ⅱ. Necessity of research development and Purpose
Later in 20th century Prof. Yadomae and Prof. Ohno, of Tokyo University of pharmacy and life, Japan, studied Sparassis crispa, the artificially cultivated medicinal mushroom for its anti-cancer effects. Clinical trials showed that oral administrati

Ⅱ. Necessity of research development and Purpose
Later in 20th century Prof. Yadomae and Prof. Ohno, of Tokyo University of pharmacy and life, Japan, studied Sparassis crispa, the artificially cultivated medicinal mushroom for its anti-cancer effects. Clinical trials showed that oral administration of Sparassis crispa powder to fourteen last stage cancer patients showed notable improvements in nine patients.
The results (Immuno modulating Activity of a β-Glucan Preparation, SCG, Extracted from a Culinary Medicinal Mushroom, Sparassis crispa Wulf.:Fr.,and Application to Cancer Patients; International Journal of Medicinal Mushrooms 2003) were published at Japanese cancer conference general meeting (2003, October, 61th), and so Sparassis crispa containing β-(1-3)-glucan is spotlighted as a new natural material used in anticancer immunotherapy in Japan. About 10 large enterprise and research institutes like Mitsuwakogyo (ミツワ興業), Yunichika(ユニチカ), Obiken Co., Ltd(應微硏), Yamatokingaku(大和菌學硏究所) etc. participate in research, output and product sale of Sparassis crispain addition to already existing Minahealth(ミナヘルス).
In Korea study on Sparassis crispais almost at its primary level. Artificial cultivation was tried out in several mushroom cultivation farms and research institutes.
About 170 cancer patients are dying per day because of the lack of proper drug for the treatment. This study expects that new hope to cancer patients and also creates new income source to mushroom farmers
III. Contents and range of research development
In Korea, although study on medicinal mushroom has grown steadily with the use of Phellinus sp., by artificial cultivation for the extraction of pharmacologically active substance and animal test were conducted to judge their toxic levels. The project not only focuses on theoretical study, but also pays more importance for the industrial production through the collection of superior fungal strains, growth, development of artificial cultivation methods, product extraction methods, search for pharmacologically active substances and its mass production.
The present study focuses on three aspects. First is the collection of superior fungal strain, development of synthetic media, favorable conditions for mass cultivation. Second is the search for pharmacologically active substances, anti-cancer agents and third is the development of different health related food products.
n this study, we developed artificial cultivation system and verified the product activity in anticancer effect at preliminary level. Now we were focusing to carry out the study in wide range to make the product. The study is in progress.

목차 Contents

• 표지 ... 1
• 제출문 ... 2
• 요약문 ... 3
• SUMMARY ... 6
• CONTENTS ... 9
• 목차 ... 11
• 제1장 총론 ... 13
• 제1절 연구개발의 필요성 ... 13
• 제2절 연구개발의 목표 및 내용 ... 20
• 제3절 연구개발 추진체계 ... 21
• 제4절 참고문헌 ... 22
• 제2장 꽃송이버섯 우량 균주의 확보 ... 25
• 제1절 균주의 확보 ... 25
• 제2절 유전자 분석을 통한 동정분류 ... 28
• 제3절 우량 균주의 선발 ... 32
• 제3장 꽃송이버섯 대량 생산체계 확립 ... 36
• 제1절 서언 ... 37
• 제2절 재료 및 방법 ... 41
• 제3절 결과 및 고찰 ... 43
• 제4절 결론 ... 69
• 제5절 참고문헌 ... 71
• 제4장 꽃송이버섯 재배방법별 생산수율 확립 ... 74
• 제1절 서언 ... 75
• 제2절 재료 및 방법 ... 77
• 제3절 결과 및 고찰 ... 79
• 제4절 적요 ... 84
• 제5절 참고문헌 ... 85
• 제 5장 꽃송이버섯 성분 및 함량 분석 ... 86
• 제1절 재료 및 방법 ... 86
• 제2절 일반성분 분석 ... 86
• 제3절 결과 및 고찰 ... 89
• 제4절 결론 ... 97
• 제6장 꽃송이버섯 다당체의 효소처리 및 면역활성에 관한 연구 ... 98
• 제1절 서론 ... 98
• 제2절 재료 및 방법 ... 100
• 제3절 결과 및 고찰 ... 104
• 제4절 결론 ... 112
• 제5절 참고문헌 ... 113
• 제7장 꽃송이버섯 분말의 경구투여 동물실험 ... 118
• 제1절 연구개요 ... 118
• 제2절 요약 ... 120
• 제3절 시험물질 및 용매물질 ... 122
• 제4절 재료 및 방법 ... 123
• 제5절 결과 ... 130
• 제6절 고찰 및 결론 ... 141
• 제8장 꽃송이버섯 다당체의 항암 면역활성과 약리작용 규명 ... 144
• 제1절 서론 ... 144
• 제2절 실험 재료 및 방법 ... 148
• 제3절 결과 및 고찰 ... 154
• 제4절 결론 ... 161
• 제5절 참고문헌 ... 163
• 제6절 관련 사진 ... 168
• 제9장 연구개발 성과 및 활용 ... 179
• 제1장 연구개발의 주요성과 ... 179
• 제2절 제품 개발 및 판매 ... 190
• 제3장 향후 연구개발 계획 및 건의사항 ... 194
• 끝페이지 ... 196