초록 ▼

Ⅳ. 연구개발결과
설사를 유발시키는 장내 병원성미생물에 대한 억제효과를 갖는 락토바실러스를 분리하고 (수탁번호: KACC81012BP, KACC81032BP, 농촌진흥청 농업유전자원정보센터), 이에 관하여 특허 출원 중에 있다(출원번호: 10-2015-0164340, 10-2015-0164341).
흑/백돼지 장내미생물생태 차이 규명, 항생제 처리에 따른 돼지 장내미생물생태변화 규명, 국내 지역별 돼지장내미생물생태 차이 규명, 성장단계별 장내미생물생태 규명, 성장단계별 장내 기능유전자 차이 확인 및 Metagenome 데

Ⅳ. 연구개발결과
설사를 유발시키는 장내 병원성미생물에 대한 억제효과를 갖는 락토바실러스를 분리하고 (수탁번호: KACC81012BP, KACC81032BP, 농촌진흥청 농업유전자원정보센터), 이에 관하여 특허 출원 중에 있다(출원번호: 10-2015-0164340, 10-2015-0164341).
흑/백돼지 장내미생물생태 차이 규명, 항생제 처리에 따른 돼지 장내미생물생태변화 규명, 국내 지역별 돼지장내미생물생태 차이 규명, 성장단계별 장내미생물생태 규명, 성장단계별 장내 기능유전자 차이 확인 및 Metagenome 데이터 분석 파이프라인 구축하였으며, 또한 돼지장내미생물생태 데이터베이스를 구축하고 NGS 기법 중 하나인 MiSeq의 데이터를 분석 할 수 있는 프로그램을 개발하였다.

Abstract ▼

In general, antibiotics were used to protect livestock animals from diseases. Another benefit of using antibiotics is a growth enhancement, known as a growth promoter. However, the mechanisms by which antibiotics enhance growth of livestock animals are not understood. In addition, using antibiotics

In general, antibiotics were used to protect livestock animals from diseases. Another benefit of using antibiotics is a growth enhancement, known as a growth promoter. However, the mechanisms by which antibiotics enhance growth of livestock animals are not understood. In addition, using antibiotics cause problems such as antibiotics resistant gene dissemination and residue of antibiotics in meat, for these reasons the use of antibiotics has been banned in many countries. One of the possible growth enhancement effects that antibiotics could bring has been believed to be gut microbiota shift. In this study, we monitored the gut microbiota shift during the antibiotics feeding trials (Tetracyclin, Tylosin) in swine. Our results suggest that antibiotics growth promoter may not directly enhance the growth of animals, but provide protection from pathogenic bacteria in early stages.In addition, we investigated swine gut microbiota according to growth stages, also compared between white and black pigs across several regions in South Korea. Our results indicated significant differences across pig breeds, regional differences, and growth stage differences. Through the course of this study, fundamental information of swine gut microbiota has been stated and effects of AGP on swine gut microbiota has also been discussed. Farm scale experiment should be done in future to confirm our results.