Background and Objectives：Leukoplakia is a descriptive term designating a white patch or plaque of the mucosa and must becomplemented by histology. The aim of this study was to analyze the laryngeal leukoplakia clinically. Materials and Method：48 patients were included from 1995 to 2001. All presented themselves with laryngeal leukoplakia in telescopic examination. Theavailable medical record are age, sex, duration of smoking, histopathological finding, treatment and follow up result. Results：Thepatients were composed of 46 males and 2 females. There were 7 patients (15%) with specific diagnostic lesion (polyps, lymphoma,tuberculosis, chronic inflammation and papilloma), 19 patients (40%) with simple hyperplasia or hyperkeratosis, 4 patients(8%) with mild dysplasia, 2 patients (4%) with moderate dysplasia, 2 patients (4%) with severe dysplasia, 2 patients (4%) withcarcinoma in situ, and 1 patient (2%) with microinvasive carcinoma and 11 patients with invasive squamous cell carcinoma. Rebiopsywas performed to 10 cases during follow up period. Conclusion：The results of our study show that the leukoplakia waspresented in 15% of all cases with specific diagnostic lesion and that the patient was treated according to their specific diagnosis.Almost all of the case with precancerous conditions were cured with cord stripping, cordectomy or radiation therapy. (Korean JOtolaryngol 2003;46:1064-9)