불소용액양치 및 불소이온도입법에 의한 불소도포가 초기법랑질탈회병소의 재석회화에 미치는 영향에 대해 알아보고자 법랑질시편에 인위적으로 초기법랑질탈회를 유발하여 하악가철성장치물에 매식한후 4명의 대상자 구강내에서 2주동안 초기법랑질탈회병소를 노출시키면서 불소처치없이 타액에 의한 자연적인 재석회화, 매일 1회 1분 동안 0.05% 불화소다용액 양치, 이온도입으로 2.0% 불화소다용액을 4분간 l회 도포한후 Vickers hardness tester로 법랑질시편의 표면미세경도, 내산성실험후 표면미세경도를 측정하였고 ...
불소용액양치 및 불소이온도입법에 의한 불소도포가 초기법랑질탈회병소의 재석회화에 미치는 영향에 대해 알아보고자 법랑질시편에 인위적으로 초기법랑질탈회를 유발하여 하악가철성장치물에 매식한후 4명의 대상자 구강내에서 2주동안 초기법랑질탈회병소를 노출시키면서 불소처치없이 타액에 의한 자연적인 재석회화, 매일 1회 1분 동안 0.05% 불화소다용액 양치, 이온도입으로 2.0% 불화소다용액을 4분간 l회 도포한후 Vickers hardness tester로 법랑질시편의 표면미세경도, 내산성실험후 표면미세경도를 측정하였고 주사전자현미경으로 표면변화를 관찰하여 다음과 같은 결과를 얻었다. ㆍ 구강내노출 실험후 표면미세경도를 측정한 결과, 구강내노출군 모두 초기법랑질탈회병소에 비해 증가된 표면미세경도를 나타내었으며(p<0.01) 타액군, 불소용액양치군, 불소이온도입군의 순으로 표면미세경도가 증가하였다. ㆍ 구강내노출 실험후 내산성실험을 행하여 표면미세경도를 측정한 결과, 구 강내노출군 모두 초기법랑질탈회병소에 비해서 높은 표면미세경도를 나타내었으며(p<0.01) 타액군, 불소용액양치군, 불소이온도입군순으로 표면미세경도가 높게 나타났다. ㆍ 표면미세경도의 변화를 초기법랑질탈회병소를 기준으로 각 실험군의 백분 율로 환산하여 비교한 결과 구강내노출 실험후에 비해 내산성실험후 타액군, 불소용액양치군, 불소이온도입군 모두 감소하였으나 불소용액양치군은 통계적으로 유의한 차이가 없었다(p=0.32). ㆍ 주사전자현미경으로 구강내노출 실험후 표면변화양상을 관찰한 결과 타액군의경우 초기법랑질탈회병소에 비해 파괴양상이 상당히 감소되었으나 미세공과 균열부위가 여러군데 관찰되었고 불소도포군의 경우 표면구조가 비교적 매끄럽고 균일하게 회복되었다.
불소용액양치 및 불소이온도입법에 의한 불소도포가 초기법랑질탈회병소의 재석회화에 미치는 영향에 대해 알아보고자 법랑질시편에 인위적으로 초기법랑질탈회를 유발하여 하악가철성장치물에 매식한후 4명의 대상자 구강내에서 2주동안 초기법랑질탈회병소를 노출시키면서 불소처치없이 타액에 의한 자연적인 재석회화, 매일 1회 1분 동안 0.05% 불화소다용액 양치, 이온도입으로 2.0% 불화소다용액을 4분간 l회 도포한후 Vickers hardness tester로 법랑질시편의 표면미세경도, 내산성실험후 표면미세경도를 측정하였고 주사전자현미경으로 표면변화를 관찰하여 다음과 같은 결과를 얻었다. ㆍ 구강내노출 실험후 표면미세경도를 측정한 결과, 구강내노출군 모두 초기법랑질탈회병소에 비해 증가된 표면미세경도를 나타내었으며(p<0.01) 타액군, 불소용액양치군, 불소이온도입군의 순으로 표면미세경도가 증가하였다. ㆍ 구강내노출 실험후 내산성실험을 행하여 표면미세경도를 측정한 결과, 구 강내노출군 모두 초기법랑질탈회병소에 비해서 높은 표면미세경도를 나타내었으며(p<0.01) 타액군, 불소용액양치군, 불소이온도입군순으로 표면미세경도가 높게 나타났다. ㆍ 표면미세경도의 변화를 초기법랑질탈회병소를 기준으로 각 실험군의 백분 율로 환산하여 비교한 결과 구강내노출 실험후에 비해 내산성실험후 타액군, 불소용액양치군, 불소이온도입군 모두 감소하였으나 불소용액양치군은 통계적으로 유의한 차이가 없었다(p=0.32). ㆍ 주사전자현미경으로 구강내노출 실험후 표면변화양상을 관찰한 결과 타액군의경우 초기법랑질탈회병소에 비해 파괴양상이 상당히 감소되었으나 미세공과 균열부위가 여러군데 관찰되었고 불소도포군의 경우 표면구조가 비교적 매끄럽고 균일하게 회복되었다.
The effect of fluoride application by mouthrinse and iontophoresis on remineralization of early caries-like lesions was investigated in vivo using acrylic mandibular removable appliance. Forty extracted third molars were collected, early caries-like lesions were created using O.1M lactic acid-sodium...
The effect of fluoride application by mouthrinse and iontophoresis on remineralization of early caries-like lesions was investigated in vivo using acrylic mandibular removable appliance. Forty extracted third molars were collected, early caries-like lesions were created using O.1M lactic acid-sodium hydroxide buffer(pH=4.0). A total of 7 enamel specimens with early caries-like lesions were mounted into the recesses of lingual surface of the appliance with sticky wax and 4 subjects wore the appliance for 14days without exposure to fluoride agent, with daily exposure to 0.05% NaF solution for 1 min. or one iontophoresis application of 2.0% NaF solution for 4 min. Each subjects wore the appliance for three separate 14-day periods ; saliva exposure, F mouthrinse, F iontophoresis test. During the intraoral periods, all subjects continued their usual dietary habits, and wore the appliance continuously except during meal times and toothbrushing, and brushed with F-free dentifrice. For analysis of remineralization effect, surface microohardness test, acid resistance test were done with Vickers hardness tester(500gm load) and the changes of enamel surface were observed with scanning electron microscopy(at 20Kv). For statistical analysis, oneway ANOVA and Duncan's multiple range test were used to test for statistical differences of surface microhardness values between early caries-like lesions and intraoral exposure(IOE) groups, and after acid resistance test(ART). The comparision of microhardness(%) between following IOE and after ART compared to the early caries-like lesions was determined using t-tests. The obtained results were as follows : 1. Surface microhardness value after intraoral exposure. IOE groups were found significantly higher mean value of surface microhardness than early caries-like lesions(p<0.01) and VHN was highest in fluoride iontophoresis group and lowest in saliva group. 2. Resistance to a controlled acid challenge was determined followingsurface microhardness testing after intraoral exposure. ART groups after intraoral exposure were found significantly higher mean value of surface microhardness than early caries-like lesions(p0.05). 4. The changes of surfaces were observed with SEM photographs(x2,000) after IOE and ART. Saliva group was guietly decreased the degree of destruction of enamel surface than early caries-like lesions but focal holes and small micropores were found in various place. Relatively homogeneous surface pattern was observed in fluoride application group.
The effect of fluoride application by mouthrinse and iontophoresis on remineralization of early caries-like lesions was investigated in vivo using acrylic mandibular removable appliance. Forty extracted third molars were collected, early caries-like lesions were created using O.1M lactic acid-sodium hydroxide buffer(pH=4.0). A total of 7 enamel specimens with early caries-like lesions were mounted into the recesses of lingual surface of the appliance with sticky wax and 4 subjects wore the appliance for 14days without exposure to fluoride agent, with daily exposure to 0.05% NaF solution for 1 min. or one iontophoresis application of 2.0% NaF solution for 4 min. Each subjects wore the appliance for three separate 14-day periods ; saliva exposure, F mouthrinse, F iontophoresis test. During the intraoral periods, all subjects continued their usual dietary habits, and wore the appliance continuously except during meal times and toothbrushing, and brushed with F-free dentifrice. For analysis of remineralization effect, surface microohardness test, acid resistance test were done with Vickers hardness tester(500gm load) and the changes of enamel surface were observed with scanning electron microscopy(at 20Kv). For statistical analysis, oneway ANOVA and Duncan's multiple range test were used to test for statistical differences of surface microhardness values between early caries-like lesions and intraoral exposure(IOE) groups, and after acid resistance test(ART). The comparision of microhardness(%) between following IOE and after ART compared to the early caries-like lesions was determined using t-tests. The obtained results were as follows : 1. Surface microhardness value after intraoral exposure. IOE groups were found significantly higher mean value of surface microhardness than early caries-like lesions(p<0.01) and VHN was highest in fluoride iontophoresis group and lowest in saliva group. 2. Resistance to a controlled acid challenge was determined followingsurface microhardness testing after intraoral exposure. ART groups after intraoral exposure were found significantly higher mean value of surface microhardness than early caries-like lesions(p0.05). 4. The changes of surfaces were observed with SEM photographs(x2,000) after IOE and ART. Saliva group was guietly decreased the degree of destruction of enamel surface than early caries-like lesions but focal holes and small micropores were found in various place. Relatively homogeneous surface pattern was observed in fluoride application group.
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