위장관 질환에 있어서 CLO검사와 H-E염색에 의한 Helicobacter Pylori 감염의 진단적 의의 (The) Study of CLO test and H-E stain for the detection of Helicobacter Pylori in Gastroduodenal diseases원문보기
1. 상부위장관 증상을 호소하는 환자 150예에서 Helicobacter pylori을 검출하기 위해 실시한 CLO검사에서 양성반응은 93예(62%), 음성반응은 53예(38%)이었다. 2. 150예 중 80예에서 얻은 위유문부 조직의 H-E stain에서 Helicobacter pylori 검출율은 정상 2예(33%), 만성표재성위염 7예(32%), 만성위축성위염 6예(26%), 만성증식성위염 2예(40%), 만성미란성위염 3예(33%), 위궤양 2예(50%), 십이지장궤양 2예(33%), 그리고 위암 3예(60%)로 총양성반응은 27예(34%), 음성반응은 53예(56%)이었다. 3. Helicobacter pylori 검출에 H-E stain을 기준으로 볼 때 CLO검사의 민감도와 ...
1. 상부위장관 증상을 호소하는 환자 150예에서 Helicobacter pylori을 검출하기 위해 실시한 CLO검사에서 양성반응은 93예(62%), 음성반응은 53예(38%)이었다. 2. 150예 중 80예에서 얻은 위유문부 조직의 H-E stain에서 Helicobacter pylori 검출율은 정상 2예(33%), 만성표재성위염 7예(32%), 만성위축성위염 6예(26%), 만성증식성위염 2예(40%), 만성미란성위염 3예(33%), 위궤양 2예(50%), 십이지장궤양 2예(33%), 그리고 위암 3예(60%)로 총양성반응은 27예(34%), 음성반응은 53예(56%)이었다. 3. Helicobacter pylori 검출에 H-E stain을 기준으로 볼 때 CLO검사의 민감도와 특이도는 각각 85%와 83%이었다. 이상의 소견으로 보아 우리나라에서 상부 위장관 질환의 전반에 걸쳐 Helicobacter pylori의 감염을 확인할 수 있었고 또 CLO검사와 내시경적 조직 검사물의 H-E 염색 방법이 이 세균의 조기 감염 진단에 상당히 유용하다고 판단되었다.
1. 상부위장관 증상을 호소하는 환자 150예에서 Helicobacter pylori을 검출하기 위해 실시한 CLO검사에서 양성반응은 93예(62%), 음성반응은 53예(38%)이었다. 2. 150예 중 80예에서 얻은 위유문부 조직의 H-E stain에서 Helicobacter pylori 검출율은 정상 2예(33%), 만성표재성위염 7예(32%), 만성위축성위염 6예(26%), 만성증식성위염 2예(40%), 만성미란성위염 3예(33%), 위궤양 2예(50%), 십이지장궤양 2예(33%), 그리고 위암 3예(60%)로 총양성반응은 27예(34%), 음성반응은 53예(56%)이었다. 3. Helicobacter pylori 검출에 H-E stain을 기준으로 볼 때 CLO검사의 민감도와 특이도는 각각 85%와 83%이었다. 이상의 소견으로 보아 우리나라에서 상부 위장관 질환의 전반에 걸쳐 Helicobacter pylori의 감염을 확인할 수 있었고 또 CLO검사와 내시경적 조직 검사물의 H-E 염색 방법이 이 세균의 조기 감염 진단에 상당히 유용하다고 판단되었다.
Since the successful isolation of Helicobacter pylori from the human gastric mucosa by Warren and Mashall on 1983, a strong association between H.pylori and chronic active gastritis, peptic ulcer, and gastric carcinoma has been recognized. The exact mechanism by which contributes to mucosal damage i...
Since the successful isolation of Helicobacter pylori from the human gastric mucosa by Warren and Mashall on 1983, a strong association between H.pylori and chronic active gastritis, peptic ulcer, and gastric carcinoma has been recognized. The exact mechanism by which contributes to mucosal damage is unknown. Recent studies have suggested fat the mast cell and neutrophil, through the release of a variety of mediators, can profoundly affect mucosal resistance to injury. H.pylori can be detected through a variety of invasive (urease testing, culture, or histologic diagnosis of endoscopic biopsies)and noninvasive(urease breath test, serologic test)diagnostic tests. Urease in the human gastric mucosa is a marks for infection with H.pylori. The author evaluated the use of rapid urease test (CLO test) and Hematoxyline-eosin stain to detect H.pylori in 150 patients (84 males, 66 females; mean age 48.3 years) with suspected gastroduodenal disease. Ninty three (62%) were positive CLO test, and 57(38%), negative. Antral biopsies were taken from 80 patients undergoing upper gastrointestinal endoscopy were assessed in a blind fashion after H-E stain and revealed H.pylori in 27 (34%) out of 80 cases. The sensitivity and specificity of the CLO test for the diagnosis of H.pylori were 85% and 83%, respectively. In conclusion, CLO test and HE stain may be the simple and useful screening tests for diagnosis of H.pylori infection.
Since the successful isolation of Helicobacter pylori from the human gastric mucosa by Warren and Mashall on 1983, a strong association between H.pylori and chronic active gastritis, peptic ulcer, and gastric carcinoma has been recognized. The exact mechanism by which contributes to mucosal damage is unknown. Recent studies have suggested fat the mast cell and neutrophil, through the release of a variety of mediators, can profoundly affect mucosal resistance to injury. H.pylori can be detected through a variety of invasive (urease testing, culture, or histologic diagnosis of endoscopic biopsies)and noninvasive(urease breath test, serologic test)diagnostic tests. Urease in the human gastric mucosa is a marks for infection with H.pylori. The author evaluated the use of rapid urease test (CLO test) and Hematoxyline-eosin stain to detect H.pylori in 150 patients (84 males, 66 females; mean age 48.3 years) with suspected gastroduodenal disease. Ninty three (62%) were positive CLO test, and 57(38%), negative. Antral biopsies were taken from 80 patients undergoing upper gastrointestinal endoscopy were assessed in a blind fashion after H-E stain and revealed H.pylori in 27 (34%) out of 80 cases. The sensitivity and specificity of the CLO test for the diagnosis of H.pylori were 85% and 83%, respectively. In conclusion, CLO test and HE stain may be the simple and useful screening tests for diagnosis of H.pylori infection.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.