Abstract ▼ AI-Helper

Adenovirus and coxsackievirus A24v were known to be associated with acute viral conjunctivitis. One hundred twenty one specimens from the patients suspected or diagnosed with viral epidemic conjunctivitis were collected in Chonbuk during July to December in 2010. We analysed the partial genome seque...

Adenovirus and coxsackievirus A24v were known to be associated with acute viral conjunctivitis. One hundred twenty one specimens from the patients suspected or diagnosed with viral epidemic conjunctivitis were collected in Chonbuk during July to December in 2010. We analysed the partial genome sequences of epidemic keratoconjunctivitis(EKC)-related human adenoviruses and hemorrhagic conjunctivitis(AHC)-related human Coxaskievirus A24 variant(CA24v). A total of 77 adenovirus strains(91.7%) and 7 CA24v strains(8.3%) were identified, and five serotypes of adenovirus and one serotype of CA24v were classified through PCR sequencing; among 77 adenovirus strains, serotype 8, 39 strains(50.6%), serotype 11, 16 strains(20.8%), serotype 19, 12 strains(15.6%), serotype 3, 6 strains(7.8%), serotype 37, 4 strains(5.2%). Adenovirus 8 was revealed as the most common serotype in this study. A phylogenetic tree was designed by DNASTAR(Madison, Wi, USA), and sequencing data were made using CLUSTAL X(version 1.81). Compared with the prototype strain, all types of adenoviruses isolated in this study showed 99.5-100% homology, and CA24v, 98.3-98.7% homology respectively.

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