Significant advances have been made in modern materials technology, especially in device manufacturing, which has facilitated the use of different materials in a variety of applications. Carbon nanotubes (CNT) are being successfully implemented in sensing, drug delivery, water purification and compo...
Significant advances have been made in modern materials technology, especially in device manufacturing, which has facilitated the use of different materials in a variety of applications. Carbon nanotubes (CNT) are being successfully implemented in sensing, drug delivery, water purification and composite materials. Therefore, CNTs must meet a wide range of criteria such as surface modification, high aspect ratio, high electrical conductivity, high porosity, non-toxicity, specificity, selectivity, and compatibility for device fabrication. In this study, we developed a chemical molecular sensor that can detect ethanol and carbon monoxide by tuning multiwalled carbon nanotube (MWCNT), and a biosensor that can detect low concentrations of C-Reactive Protein (CRP). The applicability of the 3D Poly(3,4-ethylenedioxiophene)/poly(4-styrenesulfonate) (PEDOT:PSS)-MWCNT composite for a chemical molecule sensor was investigated with different PEDOT:PSS concentrations. The chemical molecule-sensing performance of the 3D PEDOT:PSS-MWCNT composites was investigated using ethanol and carbon monoxide (CO) chemical molecule. Overall, in comparison with the pristine MWCNTs, as the PEDOT:PSS concentration increased, the 3D PEDOT:PSS-MWCNT composites exhibited increased conductivity and enhanced chemical molecule sensing performances (fast response and recovery times) to both ethanol and CO chemical molecules. Importantly, although the PEDOT:PSS coating layer reduced the number of sites for the adsorption and desorption of chemical molecules, the charge-carrier transport between the chemical molecules and MWCNTs was significantly enhanced. Thus, PEDOT:PSS can be chemically grafted to MWCNTs to enhance the connectivity and conductivity of a 3D network, leading to possible applications in chemical molecule sensors. And, we present multiple-bent multi-walled carbon nanotubes (MWCNTs) that enable the picomolar detection of C-reactive protein (CRP), which is considered to be a promising biomarker for various diseases. The MWCNTs were grown via chemical vapor deposition repeating the asymmetric catalytic CNT growth on atypical carbon nanoparticles that were generated by carbon coating on a silicon substrate. The multiple-bent MWCNTs with the carbon film (CF) possessed abundant hydrophilic functional groups (-COOH and -OH) at their bending sites, resulting in enhanced bioadhesion to collagen and platelets, compared to MWCNTs grown without a CF layer. Interestingly, the bent MWCNTs enhanced the reliability and sensitivity of the electrochemical detection at low CRP concentrations, possibly due to molecular affinity at the bent site. The bioactive bent MWCNTs can play a significant role in ultrasensitive biosensors to improve their detection limit, thereby achieving early detection and monitoring of CRP-related diseases such as cardiovascular events and melanoma.
Significant advances have been made in modern materials technology, especially in device manufacturing, which has facilitated the use of different materials in a variety of applications. Carbon nanotubes (CNT) are being successfully implemented in sensing, drug delivery, water purification and composite materials. Therefore, CNTs must meet a wide range of criteria such as surface modification, high aspect ratio, high electrical conductivity, high porosity, non-toxicity, specificity, selectivity, and compatibility for device fabrication. In this study, we developed a chemical molecular sensor that can detect ethanol and carbon monoxide by tuning multiwalled carbon nanotube (MWCNT), and a biosensor that can detect low concentrations of C-Reactive Protein (CRP). The applicability of the 3D Poly(3,4-ethylenedioxiophene)/poly(4-styrenesulfonate) (PEDOT:PSS)-MWCNT composite for a chemical molecule sensor was investigated with different PEDOT:PSS concentrations. The chemical molecule-sensing performance of the 3D PEDOT:PSS-MWCNT composites was investigated using ethanol and carbon monoxide (CO) chemical molecule. Overall, in comparison with the pristine MWCNTs, as the PEDOT:PSS concentration increased, the 3D PEDOT:PSS-MWCNT composites exhibited increased conductivity and enhanced chemical molecule sensing performances (fast response and recovery times) to both ethanol and CO chemical molecules. Importantly, although the PEDOT:PSS coating layer reduced the number of sites for the adsorption and desorption of chemical molecules, the charge-carrier transport between the chemical molecules and MWCNTs was significantly enhanced. Thus, PEDOT:PSS can be chemically grafted to MWCNTs to enhance the connectivity and conductivity of a 3D network, leading to possible applications in chemical molecule sensors. And, we present multiple-bent multi-walled carbon nanotubes (MWCNTs) that enable the picomolar detection of C-reactive protein (CRP), which is considered to be a promising biomarker for various diseases. The MWCNTs were grown via chemical vapor deposition repeating the asymmetric catalytic CNT growth on atypical carbon nanoparticles that were generated by carbon coating on a silicon substrate. The multiple-bent MWCNTs with the carbon film (CF) possessed abundant hydrophilic functional groups (-COOH and -OH) at their bending sites, resulting in enhanced bioadhesion to collagen and platelets, compared to MWCNTs grown without a CF layer. Interestingly, the bent MWCNTs enhanced the reliability and sensitivity of the electrochemical detection at low CRP concentrations, possibly due to molecular affinity at the bent site. The bioactive bent MWCNTs can play a significant role in ultrasensitive biosensors to improve their detection limit, thereby achieving early detection and monitoring of CRP-related diseases such as cardiovascular events and melanoma.
주제어
#Carbon nanotube Chemical molecular sensor Biosensor Ethanol Carbon monoxide C-reactive protein
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