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Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.19 no.5, 1996년, pp.411 - 415
Sung, Bo-Ko (Division of Applied Science Korea Institute of Science and Technology) , Lee, Yong-Sup (Division of Applied Science, Korea Institute of Science and Technology) , Lee, Jae-Yeol (Division of Applied Science, Korea Institute of Science and Technology) , Ham, Won-Hoon (College of Pharmacy, Sungkyunkwan University) , Park, Hokoon (Division of Applied Science, Korea Institute of Science and Technology)
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A series of aminothiazolylcephalosporin derivatives (1a-1c) having pyridinylethenyl group at C-3 position was prepared starting from phosphonium salt 3 and 2-, 3- or 4-pyridinecarboxal-dehyde and the antibacterial activity of these compounds was investigated. Among them, 4-pyridinylethenyl derivativ...
Aburaki, S., Kamachi, H., Narita, Y., Okamura, J. and Naito, T., (Bristol-Myers): Cephalosporins. U. S. Pat. 4,406,899, Sep. 27 (1983).
J. Antibiotics M. Kume 46 177 1993 10.7164/antibiotics.46.177 Kume, M., kubota, T., Kimura, Y., Nakashimizu, H., Motokawa, K. and Nakano, M., Synthesis and structure-activity relationships of new 7β-[(Z)-2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamido] cephalosporins with 1,2,3-triazole in C-3 side chain.J. Antibiotics, 46, 177-192 (1993).
J. Antibiotics Y. S. Lee 49 405 1996 10.7164/antibiotics.49.405 Lee, Y. S., Lee, Y. S. and Park, H., Synthesis and biological activities of C-3 direct heterocyclylcarbon-substituted novel cephalosporins.J. Antibiotics, 49, 405-407 (1996).
J. Antibiotics N. Nagano 44 422 1991 10.7164/antibiotics.44.422 Nagano, N., Satoh, M. and Hara, R., Studies on β-lactam antibiotics III. Synthesis and antibacterial activities of new 3-(1,3-dithiolan-2-yl)cephalosporins, YM-22508, YM-16457 and their prodrug-type est-ers.J. Antibiotics, 44, 422-428 (1991).
J. Antibiotics E. Nakayama 43 1122 1990 10.7164/antibiotics.43.1122 Nakayama, E., Watanabe, K., Miyauchi, M., Fujimoto, K. and Ide J., Studies on orally active cephalosporin esters. VI. Synthesis and antimicrobial activity of 3-(3-isoxazolyl)oxymethylcephalosporin derivatives.J. Antibiotics, 43, 1122-1130 (1990).
J. Antibiotics H. Park 47 606 1994 10.7164/antibiotics.47.606 Park, H., Lee, J. Y., Lee, Y. S., Park, J. O., Ko, S. B. and Ham, W.-H., Synthesis and biological activities of C-3 heterocyclylcarbon-substituted new cephalosporins,J. Antibiotics, 47, 606-608 (1994).
Tetrahedron Lett. S. Torii 23 2187 1982 10.1016/S0040-4039(00)87295-0 Torii, S., Tanaka, H., Saito, N., Siroi, T., Sasaoka, M. and Nokami, J., Penicillin-cephalosporin conversion III. A novel route to 3-chloromethyl-Δ3-cephems.Tetrahedron Lett., 23, 2187-2188 (1982).
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