• 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보


Panax-ginseng saponin has been known to exert various pharmacological effects on cellular metabolism. This study was performed to determine the effect of ginseng saponin on gap junction channel-mediated intercellular communication, using an established in vitro system of reconstituted gap junction channels. Gap junction channels are a specialized plasma membrane fraction, which are permeable to relatively large water-soluble molecules. The sucrose permeable property of reconstituted gap junction channels was completely inhibited with 0.1 % (w/v) of ginseng saponin. We also compared the effect of ginseng saponin with that of Triton X-100, a nonionic detergent, on the same system. Triton X-100 showed significantly different effect on sucrose-permeability of gap junction channel from that was affected by ginseng saponin. The structures of liposomes containing gap junction channels was significantly destroyed by Triton X-100.

저자의 다른 논문

참고문헌 (22)

  1. Several physiological functions and metabolism of ginsenosides in the animal body , Joo,C.N. , Korean J. Ginseng Sci. / v.17,pp.250-286, 1993
  2. Cyclic AMP-dependent phosphorylation of an immunoaffinity-purified homotetrameric IP3 receptor increases Ca$^{2+}$ influx in reconstituted lipid vesicles , Nakade,S.;Rhee,S.K.;Hamanaka,H.;Mikoshiba,K. , J. Biol. Chem. / v.269,pp.6735-3742, 1994
  3. Mechanisms of tumor promotion: potential role of intercellular communication , Trosko,J.E.;Chang,C.C.;Metcalf,A. , Cancer Invest. / v.6,pp.511-526, 1983
  4. Cleavage of structural proteins during the assembly of the gead of bacteriohage T4 , Laemmli,U.K. , Nature / v.227,pp.680-686, 1970
  5. Transport-specific isolation of large channels reconstituted into lipid vesicles , Harris,A.L.;Walter,A.;Zimmerberg,J. , J. Membr. Biol. / v.109,pp.243-250, 1989
  6. Purification of connexin32 by monoclonal antibody immunoaffinity chromatography , Rhee,S.K.;Paul,D.;Harris,A.L. , FASEB J. / v.3,pp.2188a, 1989
  7. Nerve growth factor-like immunoreactive substance in Panax ginseng extract , Murase,K.;Yamamoto,T.;Hayashi,K. , Biosci. Biotech. Biochem. / v.58,pp.1638-1641, 1994
  8. Inhibitory effect of ginseng on proliferation of cultured mouse mesangial cells , Yokozawa,T.;Iwano,M.;Dohi,K.;Hattori,M.;Oura,H. , Nippon Jizo Gakkai Shi. / v.36,pp.13-18, 1994
  9. Relationship between antiproliperative activity for target acetylenic alcohol, panaxydol, and its affinity for target cell membrane , Matsunaga,H.;Saita,T.;Nagumo,F.;Mori,M;Katano,M. , Japanese J. Cancer & Chemotherapy / v.21,pp.2585-2589, 1994
  10. Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions , Goodenough,D.A.;Paul,D.L.;Jesaitis,L. , J. Cell Biol. / v.107,pp.1817-1824, 1988
  11. Modulation of cell junctions during differentiation of the chicken otocyst sensory epithelium , Ginzberg,R.D.;Gilula,N.B. , Dev. Biol. / v.68,pp.110-129, 1979
  12. Tang,W.C.;Eisenbrand,G. , Chinese drugs of plant origin: chemistry, pharmaclogy and use in traditional and modern medicine / v.,pp., 1992
  13. Connexin family of gap junction proteins , Beyer,E.C.;Paul,D.L.;Goodenough,D.A. , J. Membr. Biol. / v.116,pp.187-194, 1990
  14. Hertzberg,E.L.;Johnson,R.G. , Gap Junctions / v.,pp., 1985
  15. Vasopressin-angiotensin II- and α₁-adrenergic-induced inhibition of Ca$^{2+}$ transport by rat liver plasma membrane vesicles , Prpic,V.;Green,K.C.;Blackmore,P.F.;Exton,J.H. , J. Biol. Chem. / v.259,pp.1382-1385, 1984
  16. Junctional intercellular communication: The cell-to-cell membrane channel , Loewenstein,W.R. , Physiol. Rev. / v.61,pp.829-912, 1981
  17. Junctional intercellular communication and the control of growth , Loewenstein,W.R. , Biochim. Biophys. Acta. / v.560,pp.1-65, 1979
  18. Inhibition of tumor angiogenesis and mutagenesis by a saponin of Panax ginseng, ginsenoside-Rb2 , Sato,K.;Mochizuki,M.;Saiki,I.;Yoo,Y.C.;Samukawa,K.;Azuma,I. , Biol. Pharm. Bull. / v.17,pp.63-639, 1994
  19. Further evidence for the involvement of gap junctional intercellular communication and maintenance of transformed foci in BALB/c 3T3 cells , Yamasaki,H.;Katoh,F. , Cancer Res. / v.48,pp.3490-3495, 1988
  20. Physiology and pharmacology of gap junctions , Spray,D.C.;Bennett,M.V.L. , Annu. Rev. Physiol. / v.47,pp.281-303, 1985
  21. Cell coupling and cell communication during embryogenesis , Sheridan,J.D.;Poste,H.(ed.);Nicholson,G.L.(ed.) , The cell surface in animal embryogenesis / v.,pp.409-447, 1976
  22. Ginseng rootevidence for numerous regulatory peptides and insulinotropic activity , Zhang,T.;Hoshino,K.;Iguchi,K.;Ishikawa,J.;Mochizuki,T.;Takatsuka,N.;Yanaihara,C.;Yokota,M.;Greeley,G.H.;Yanaihara,N. , Biomed. Res. / v.11,pp.49-54, 1990

이 논문을 인용한 문헌 (0)

  1. 이 논문을 인용한 문헌 없음


원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일