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NTIS 바로가기Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.19 no.4, 1996년, pp.321 - 325
Cho, Won-Jea (College of Pharmacy, Chonnam National University) , Yoo, Su-Jeong (College of Pharmacy, Chonnam National University) , Chung, Byung-Ho (College of Pharmacy, Chonnam National University) , Choi, Bo-Gil (College of Pharmacy, Chonnam National University) , Cheon, Seung-Hoon (College of Pharmacy, Chonnam National University) , Whang, Soon-Ho (College of Pharmacy, KyungHee University) , Kim, Sin-Kyu (College of Pharmacy, KyungHee University) , Kang, Boo-Hyon (Screening and Toxicology Research Center, Korea Research Institute of Chemical Technology) , Lee, Chong-Ock (Screening and Toxicology Research Center, Korea Research Institute of Chemical Technology)
Aiming at the development of anticancer agents by modification of phenolic benzo[c]phenanthridine alkaloid, additional hydroxyl group was put on C10 position of fagaridine (1) by a biomimetic synthetic procedure to afford 10-hydroxyfagaridine (12). All of the synthetic intermediates were also scree...
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