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NTIS 바로가기Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.22 no.1, 1999년, pp.68 - 71
Im, Cha-Euk (College of Pharmacy, Chung-Ang University) , Oh, Jung-Suk (College of Pharmacy, Chung-Ang University) , Yim, Chul-Bu (College of Pharmacy, Chung-Ang University)
The 6,6-dibromopenam (6) was treated with CH3MgBr and carbaldehyde 5 to afford the hydroxy compound 7, which was reacted with acetic anhydride to give acetoxy compound 8. The deacetobromination of 8 with zinc and acetic acid gave 6-exomethylenepenams, E-isomer 10 and Z-isomer 9, which was oxidized t...
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