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Abstract ▼ AI-Helper

The types of exposure data needed in an industry-based study depend on the diseases of interest and the study design to be used. The best situation occurs when we have quantified personal exposure estimates for the agents of interest, the least informative case occurs when we have only knowledge of ...

The types of exposure data needed in an industry-based study depend on the diseases of interest and the study design to be used. The best situation occurs when we have quantified personal exposure estimates for the agents of interest, the least informative case occurs when we have only knowledge of the fact of employment in a plant, industry, or trade where exposure probability is high. Exposure information for most industry-based studies falls somewhere between these tow extremes. Job exposure matrices(JEM) are designed to link information on occupation with information on exposure to specific workplace hazards. Some forms of systematic error of bias may be less likely to occur in studies that utilize job-exposure matrices to indirectly infer exposures from job titles than in studies that assess exposures by asking subjects about their past exposure. JEM can be used effectively in industry-based studies for historic cohort studies, case-control study to assist with the retrospective assessment of occupational exposures among workers whose individual exposure histories are unavailable. JEM generally consist of a computerized database that links information about job categories and likely exposures. These two major axes may be stratified by calendar time. This article reviews the design of JEM in support of industry-based studies. Specific matrices may find broader applicability along with the increasing availability of detailed hygienic data.

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