최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology, v.10 no.1, 2002년, pp.37 - 42
Brain drug targeting through the blood-brain barrier (BBB) in vivo is possible with peptidornirnetic monoclonal antibodies that undergo receptor-mediated transcytosis through the BBB. Monoclonal antibody to the rat transferrin receptor, such as the OX26 was studied in rats as a transport vector thro...
Bickel, U., Yoshikawa, T. and Pardridge, W. M. (1993). Deliveiy of peptides and proteins through the blood-brain barrier. Adv. Drug DeIivery Rev., 10, 205-245
Gibaldi, M. and Perrier, D. (1982). Pharmacokinetics, pp. 1- 329. Marcel Dekker Inc., New York
Jaenisch, R. (1988). Transgenic animals. Science, 240, 1468-1474
Jeffferries, W. A., Brandon, M. R., Williams, A. F. and Hunt, V. (1985). Analysis of lymphopoietic stem cells with a monoclonal antibody to the transferrin receptor. Im-munology, 54, 333-341
Kang, Y.S. (1997). Vector-mediated delivcry of $^{125}I$ -labeled opioid peplide, [Lys7]dermorphin (K7DA), thhrough the blood-brain barrier. J. Appl. Pharmacol., 5, 53-58
Kang, Y. S., Boado, R. J. and Pardridgc, W. M. (1995). Phar-macokinetics and organ clearance of a 3'-biotiny1ated, internally [ $^{32}P$ ]-labeled phosphodiestcr oligodeoxynucieo-tide coupled to a neutral avidin/monoclonal antibody conjugate. Drug Metabol. Dispos., 23, 1, 55-59
Kang, Y. S. and Kim, J. M. (1999). Permeability of a capsaicin derivative, [ $^{14}C$ ]DA-5018 to blood-brain barrier coirected with HPLC method. Arch. Pharm. Res., 22, 2, 99-105
Kang, Y. S. and Kim, Y. J. (2000). The simple in vivo cvaluation method for blood-brain barrier permeability of drugs in mice. J. Kor. Pharm. Sci., 30, 99-105
Kang, Y. S. and Pardridge, W. M. (1994). Use of neutral avidin improves phamiacokmetics and brain delivery of biotin bound to an avidin-monoclonal antibpdy conjugate. J. Pharm. Exp. Ther., 269, 344-350
Kissel, K., Hamm, S., Schulz, M., Vecchi, A., Garlanda, C. and Engelhardt, B. (1998). Immunohistochemical 10caliza-tion of the murine transferrin receptor (TfR.) on blood-tissue barriers using a novel anti-TfR monoclonal antibody. His-tochem. Cell Biol., 110, 63-72
Lee, H. J., Engelhardt, B., Lesley, J., Bickel, U. and Pardndge, W.M. (2000). Targeting rat anti-mousc transferrin receptor monoclonal antibodies through the blood-brain barrier in mouse. J. Pharm. Exp. Ther., 292, 1048-1052
Pardridge, W. M., Boado, R. J. and Kang, Y. S. (1995a). Vector-mediated delivery of a polyamide ('peptide') nucleic acid analogue through the blood-brain barrier invivo. Proc. Natl. Acad. Sci. USA, 92, 5592-5596
Pardridge, W. M., Kang, Y. S., Yang, J. and Buciak, J. L. (1995b). Enhanced cellular uptake and and in vivo biodistribulion of a monoclonal antibody following cationi-zation.J. Pharm. Sci., 84, 943-948
Pardridge, W. M., Buciak, J. L., Friden, P. M. (1991). Selective transport of anti-transferin rcceptor antibody through the blood-brain barrier in vivo. J. Pharm. Exp. Ther., 259, 66.70
Pardridge, W. M., Kang, Y. S., Diagne, A. and Zack, J. A. (1996). Cationized hypehimnune immunoglobulms: Phar-macokinetics, toxicity evaluation and treatmcnt of human immunodeficiency virus-infected human-peripheral blood lymphocytes-sevcre combined immune deficiency mice.J. Pharm. Exp. Ther., 276, 246-252
Pardridge, W. M., Kang, Y. S. and Buciak, J. L. (1994). Transport of human recombinant, brain-dcrived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery. Pharm. Res., 11, 5, 738-746
Pardridge, W. M., Kang, Y. S., Buciak, J. L. and Yang, J. (1995). Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate. Pharm. Res.., 12, 6, 807-816
Pardridge, W. M.. Kang, Y. S., Yang, J. and Buciak, J. L. (1995). Enhaiiced cellular uptake and in vivo biodistribution of anti-ras monoclonal anlibody following cationization. J. Pharm. Sci., 84, 8, 943-948
Smith, Q. R. (1996). Brain perfusion system for studies of drug uptake and metabolism in thc central nervous system: In Models for assessing drug absorption and mctabolism, Plenum Press, New York, pp. 285-307
Takasato, Y, Rapoport, S. I. and Smith, Q. R. (1984). An in situ brain perfusion technique to sludy cerebrovascular transport in the rat. Am. J. Phvsiol., 247, H484-493
Triguero, D., Buciak, J. B. and Pardridge, W. M. (1990). Capillary depletion method for quantifying blood-brain barrier transcytosis of circulating peptides and plasma proteins. J. Neurochem., 54, 1882-1888
Wu, D., Yang, J. and Pardridge, W. M. (1997). Drug targeting of a peptide radiopharmaceutical through the primate b100d-brain barrier in vivo with a monoclonal antibody to the human insulin reccptor. J. CIin. Invest., 100, 1804-1812
해당 논문의 주제분야에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.