Lee WonMyo
(Department of Food Science and Nutrition, Dankook University)
,
Kim EulSang
(Department of Food Science and Nutrition, Dankook University)
,
Ha Aewha
(Department of Social and Behavioral Sciences, University of North Texas Health Science Center)
,
Ximena Urrutia-Rojas
(Department of Social and Behavioral Sciences, University of North Texas Health Science Center)
Objective: The purpose of this study was to determine serum antioxidant nutrients and the relationship between serum antioxidants and risks of chronic diseases in obese Korean children Methods: Normal weight Korean school children (0=170), mean age of 11.5$\pm$1.5, and obese (body fat mas...
Objective: The purpose of this study was to determine serum antioxidant nutrients and the relationship between serum antioxidants and risks of chronic diseases in obese Korean children Methods: Normal weight Korean school children (0=170), mean age of 11.5$\pm$1.5, and obese (body fat mass > $28\%$) children (0=176), mean age of 11.0$\pm$1.8, were recruited Fat mass ($\%$) was determnined by Bioelectrical Impedance (BEI), and body mass index (BMI) was calculated Fasting blood was collected to measure serum antioxidant nutrients, vitamin A, vitamin E and zinc. Serum lipid profiles including total cholesterol (TC), high density cholesterol (HDL) and triglyceride (TG), and blood glucose, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPI) were also determined. Differences in serum blood measurements between obese and normal children were assessed by independent t test. Pearson's correlation analysis was used to determine the relationship between variables. Results: Blood glucose, GPT, total cholesterol, and triglycerides concentrations were significantly higher among obese boys, compared to normal boys (p<005). Significantly lower concentrations of serum vitamin E, after adjustment for TG and TC, was shown in obese boys (0.26 mg/mg) and obese girls (0.31 mg/mg), compared to normal boys (0.36 mg/mg) and girls (0.38 mg/mg) (p<0.05). Fat mass ($\%$) was negatively con-elated with serum vitamin A and vitamin E. Conclusion: Obese Korean children showed insufficient serum vitamin E concentration and increased risk for diabetes, atherosclerosis, and liver disease. Since lower vitamin E concentration was negatively con-elated with atherogenic index, improved vitamin E status in children may decrease the risk of atherosclerosis later in life.
Objective: The purpose of this study was to determine serum antioxidant nutrients and the relationship between serum antioxidants and risks of chronic diseases in obese Korean children Methods: Normal weight Korean school children (0=170), mean age of 11.5$\pm$1.5, and obese (body fat mass > $28\%$) children (0=176), mean age of 11.0$\pm$1.8, were recruited Fat mass ($\%$) was determnined by Bioelectrical Impedance (BEI), and body mass index (BMI) was calculated Fasting blood was collected to measure serum antioxidant nutrients, vitamin A, vitamin E and zinc. Serum lipid profiles including total cholesterol (TC), high density cholesterol (HDL) and triglyceride (TG), and blood glucose, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPI) were also determined. Differences in serum blood measurements between obese and normal children were assessed by independent t test. Pearson's correlation analysis was used to determine the relationship between variables. Results: Blood glucose, GPT, total cholesterol, and triglycerides concentrations were significantly higher among obese boys, compared to normal boys (p<005). Significantly lower concentrations of serum vitamin E, after adjustment for TG and TC, was shown in obese boys (0.26 mg/mg) and obese girls (0.31 mg/mg), compared to normal boys (0.36 mg/mg) and girls (0.38 mg/mg) (p<0.05). Fat mass ($\%$) was negatively con-elated with serum vitamin A and vitamin E. Conclusion: Obese Korean children showed insufficient serum vitamin E concentration and increased risk for diabetes, atherosclerosis, and liver disease. Since lower vitamin E concentration was negatively con-elated with atherogenic index, improved vitamin E status in children may decrease the risk of atherosclerosis later in life.
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문제 정의
The purpose of this study was to determine whether obese children have increased risk for chronic diseases such as diabetes, atherosclerosis, and obesity related liver diseases, as well as altered antioxidant nutrients status. This study also sought to determine whether those health risk factors are associated with antioxidant status.
Therefore, the purpose of this study was to determine whether obese children have decreased antioxidant nutrients including zinc and whether decreased antioxidant nutrients are associated with health risk factors of diabetes, arthrosclerosis, and liver disease.
The purpose of this study was to determine whether obese children have increased risk for chronic diseases such as diabetes, atherosclerosis, and obesity related liver diseases, as well as altered antioxidant nutrients status. This study also sought to determine whether those health risk factors are associated with antioxidant status. In this study, obese children showed higher blood glucose, GPT, total blood cholesterol and triglyceride than normal children (p<0.
대상 데이터
Obese children were selected from “Camps for Weight Control in Children" which were held during the summer of 1998. Age and sex-matched normal children were selected from 2 elementary schools, from July 1998 to December 1998, based on their school health records. A letter of invitation describing the project, an informed consent form, and a questionnaire were sent to the children's families three weeks prior to the study.
The 옹ubjects of this study were 170 normal and 176 obese school children in Seoul, Korea, and surrounding Provinces. Obese children were selected from “Camps for Weight Control in Children" which were held during the summer of 1998.
데이터처리
05. Differences in serum vitamin levels between obese and normal children were assessed by independent t test. Pearson's correlation analysis was used to determine relationships between variables.
Differences in serum vitamin levels between obese and normal children were assessed by independent t test. Pearson's correlation analysis was used to determine relationships between variables. The statistical analysis was performed with SPSS com puter software (Chicago, USA).
성능/효과
In conclusion, obese Korean children showed higher risks of obesity related chronic diseases, and their serum vitamin E concentrations were significantly depleted. Therefore, careful monitoring of those health indices in obese children is needed.
In this study, no differences of serum zinc between normal and obese Korean children and no correlations of zinc and otfier health indices were found. One possible explanation for the result of this study is that zinc deficiency is maybe related to the duration of obesity; therefore, it may not be evident in children.
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