Kim, W.K.
(Dept. of Animal Science, College of Life and Environmental Sciences, Korea University)
,
Kim, M.H.
(Dept. of Animal Science, College of Life and Environmental Sciences, Korea University)
,
Seo, D.S.
(Dept. of Animal Science, College of Life and Environmental Sciences, Korea University)
,
Lee, C.Y.
(Regional Animal Industry Research Center)
,
Suk, Y.O.
(Department of Applied Animal Science, Sahmyook University)
,
Ko, Y.
(Dept. of Animal Science, College of Life and Environmental Sciences, Korea University)
Increasing of body weight has been one of the important economic factors in the poultry industry. Insulin-like growth factor (IGF)-I is a polypeptide that serves to regulate muscle development and body growth. Moreover, IGF-I is related to feed efficiency. However, there are few studies regarding th...
Increasing of body weight has been one of the important economic factors in the poultry industry. Insulin-like growth factor (IGF)-I is a polypeptide that serves to regulate muscle development and body growth. Moreover, IGF-I is related to feed efficiency. However, there are few studies regarding the regulatory roles of chicken IGF-I/-II compared with that of mammals. Especially, the Korean Native Ogol Chicken (KNOC) has a lean body growth and its body weight is generally lighter than the broiler chicken. Therefore, this study was conducted to investigate associations among serum IGF-I/-II concentration, feed efficiency, and body growth in KNOC. The body weight and feed intake of KNOC were recorded from 20 to 36 weeks at 2 weeks intervals, and blood was taken every 2 weeks. Serum IGF-I/-II were measured by RIA. Chickens were divided into two groups, high and low serum IGF-I concentration. Generally, feed efficiency and growth performance (body weight and weight gain) in the high serum IGF-I group were higher than those of the low group during the experimental period. In particular, the body weight of the IGF-I high group were significantly different from those of the IGF-I low group at 34 and 36 weeks, respectively (p<0.05). Moreover, body weight, weight gain, and feed efficiency had a significant correlation with serum IGF-I at several weeks (p<0.05 and p<0.01). These results show that IGF-I plays an important role in body growth and suggests a possibility that serum IGF-I could be used as a selection marker for body growth in KNOC.
Increasing of body weight has been one of the important economic factors in the poultry industry. Insulin-like growth factor (IGF)-I is a polypeptide that serves to regulate muscle development and body growth. Moreover, IGF-I is related to feed efficiency. However, there are few studies regarding the regulatory roles of chicken IGF-I/-II compared with that of mammals. Especially, the Korean Native Ogol Chicken (KNOC) has a lean body growth and its body weight is generally lighter than the broiler chicken. Therefore, this study was conducted to investigate associations among serum IGF-I/-II concentration, feed efficiency, and body growth in KNOC. The body weight and feed intake of KNOC were recorded from 20 to 36 weeks at 2 weeks intervals, and blood was taken every 2 weeks. Serum IGF-I/-II were measured by RIA. Chickens were divided into two groups, high and low serum IGF-I concentration. Generally, feed efficiency and growth performance (body weight and weight gain) in the high serum IGF-I group were higher than those of the low group during the experimental period. In particular, the body weight of the IGF-I high group were significantly different from those of the IGF-I low group at 34 and 36 weeks, respectively (p<0.05). Moreover, body weight, weight gain, and feed efficiency had a significant correlation with serum IGF-I at several weeks (p<0.05 and p<0.01). These results show that IGF-I plays an important role in body growth and suggests a possibility that serum IGF-I could be used as a selection marker for body growth in KNOC.
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문제 정의
Collectively, due to such contradictory findings, studies are required to clarify regulatory roles of IGF-I in avian growth physiology. Therefore, this study was conducted to elucidate the association among serum IGF-I/-II concentration, body growth, and feed efficiency, and to investigate the possibility of improving both body weight and feed efficiency by serum IGF-I concentration in KNOC.
제안 방법
In order to investigate whether a link between IGF-I concentration and feed efficiency exists, two groups were compared with respect to serum IGF-I and feed efficiency. Similarly to a weight gain pattern, a significant difference was not found and the IGF-I high group tended to show higher feed efficiency than the IGF-I low group (Figure 5).
These indicate that the relationships between IGF-I and body growth is not apparent in poultry. Therefore, the present study analyzed the concentrations of IGF-I/-II, feed efficiency, and body growth to clarify the roles of IGF-I in body growth of KNOC as a model and to furthermore investigate the possibility that serum IGF-I concentration could be used as a selection marker for body growth in chicken.
대상 데이터
KNOCs were purchased from Korean Native Ogol Chicken Breeding Farms (Yeonsan, Korea). After acclimation, they were raised at the Sahmyook University Animal Breeding Center. A total of 50 female KNOC were kept in individual cages (40 cm high, 25 cm wide and 35 cm deep), and fed a commercial boiler diet (Kang et al.
KNOCs were purchased from Korean Native Ogol Chicken Breeding Farms (Yeonsan, Korea). After acclimation, they were raised at the Sahmyook University Animal Breeding Center.
성능/효과
In conclusion, the body weight, weight gain, and feed efficiency in the serum IGF-I high group were higher than those in the serum IGF-I low group during the experimental period. Moreover, significantly positive correlations of serum IGF-I concentration with body weight, weight gain, and feed efficiency were observed, suggesting that IGF-I directly promotes not only feed efficiency but also weight gain, resulting in increased body growth of KNOC.
In conclusion, the body weight, weight gain, and feed efficiency in the serum IGF-I high group were higher than those in the serum IGF-I low group during the experimental period. Moreover, significantly positive correlations of serum IGF-I concentration with body weight, weight gain, and feed efficiency were observed, suggesting that IGF-I directly promotes not only feed efficiency but also weight gain, resulting in increased body growth of KNOC. Collectively, this study shows that serum IGF-I plays an important role in the improvement of body growth and suggests a possibility that serum IGF-I could be used as a selection marker for body growth in KNOC.
참고문헌 (44)
Auchtung, T. L., E. E. Connor, S. M. Barao, L. W. Douglass and G. E. Dahl. 2001. Use of growth hormone response to growth hormone-releasing hormone to determine growth potential in beef heifers. J. Anim. Sci. 79:1566-1572.
Bacon, W. L., K. E. Nestor, D. A. Emmerson, R. Vasilator-Younken and D. W. Long. 1993. Circulating IGF-I in plasma of growing male and female turkeys of medium and heavy weight lines. Domest. Anim. Endocrinol. 10:267-277.
Ballard, F. J., R. J. Johnson, P. C. Owens, G. L. Francis, F. M. Upton, J. P. McMurtry and J. C. Wallace. 1990. Chicken insulin-like growth factor-I: amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79:459-468.
Bass, J., M. Oldham, R. Sharma and R. Kambaddur. 1999. Growth factors controlling muscle development. Domest. Anim. Endocrinol. 17:191-197.
Beccavin, C., B. Chevalier, L. A. Cogburn, J. Simmon and M. J. Duclos. 2001. Insulin-like growth factors and body growth in chickens divergently selected for high and low growth rate. J. Enodocrinol. 168:297-306.
Buyse, J. and E. Decuypere. 1999. The role of the somatotrophic axis in the metabolism of the chicken. Domest. Anim. Endocrinol. 17:245-55.
Colon, M. A. and K. Kita. 2002. Muscle protein synthesis rate is altered in response to a single injection of insulin-like growth factor-I in seven day-old Leghorn chicks. Poult. Sci. 81:1543-1547.
Czerwinski, S. M., J. M. Cate, G. Francis, F. Tomas, D. M. Brocht and J. P. McMurtry. 1998. The effect of insulin-like growth factor-I (IGF-I) on protein turnover in the meat-type chicken (Gallus domesticus). Comp. Biochem. Physiol. C. Pharmacol. Toxicol. Endocrinol. 119:75-80.
Decuypere, E., F. R. Leenstra, J. Buyse, L. M. Huybrechts, F. C. Buonomo and L. R. Berghman. Plasma levels of growth hormone and insulin-like growth factor-I and -II from 2 to 6 weeks of age in meat-type chickens selected for 6-week body weight or for feed conversion and reared under high or normal environmental temperature conditions. Reprod. Nutr. Dev. 33:361-372.
Duclos, M. J., C. Beccavin and J. Simon. 1999. Genetic models for the study of insulin-like growth factor (IGF) and muscle development in birds compared to mammals. Domest. Anim. Endocrinol. 17:231-243.
Etherton, T. D. and R. Kensinger. 1984. Endocrine regulation of fetal and postnatal meat animal growth. J. Anim. Sci. 59:511-528.
Gonzales, E., J. Buyse, J. R. Sartori, M. M. Loddi and E. Decuypere. 1999. Metabolic disturbance in mail broilers of different strains. 2. Relationship between the thyroid and somatotropic axes with growth rate and mortality. Poult. Sci. 78:516-521.
Guernec, A., C. Berri, B. Chevalier, N. Wacrenier-Cere, E. Le Bihan-Duval and M. J. Duclos. 2003. Muscle development, insulin-like growth factor-I and myostatin mRNA levels in chickens selected for increased breast muscle yield. Growth Horm. IGF. Res. 13:8-18.
Gultom, D., A. Songsang and U. Ter Meulen. 2001. The effect of chlorocholine chloride (CCC) inclusion in the diets of growing hens on growth rate, oestrogen levels and the onset of lay. J. Anim. Physiol. Anim. Nutr. (Berl). 85:1-8.
Humbe1, R. E. 1990. Insulin-like growth factors I and II. Eur. J. Biochem. 190:445-462.
Huybrechts, L. M., E. Decuypere, J. Buyse, E. R. Kuhn and M. Tixier-Biochard. 1992. Effect of recombinant human insulinlike growth factor-I on weight gain, fat content, and hormonal parameters in broiler chickens. Poult. Sci. 71:181-187.
Jones, J. I. and D. R. Clemmons. 1995. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16:2-34.
Kang, W. J., D. S. Seo and Y. Ko. 2003. Association among egg productivity, granulose layer IGF-I and ovarian IGF-I in Korean Native Ogol Chicken. Asian-Aust. J. Anim. Sci. 16:325-330
Kcoamis, H., D. C. Kirkpatrick-Keller, H. Klandorf and J. Killefer. 1998. In ovo administration of recombinant human insulin-like growth factor-I alters postnatal growth and development of the broiler chicken. Poult. Sci. 77:1913-1919.
Kita, K., S. Kato, M. Amanyaman, J. Okumura and H. Yokota. 2002. Dietary L-carnitine increases plasma insulin-like growth factor-I concentration in chicks fed a diet with adequate dietary protein level. Br. Poult. Sci. 43:117-121.
Kocamis, H., D. C. McFarland and J. Killefer. 2001. Temporal expression of growth factor genes during myogenesis of satellite cells derived from the biceps femoris and pectoralis major muscles of the chicken. J. Cell. Physiol. 186:146-152.
Lee, C. Y. and D. M. Henricks. 1990. Comparisons of various acidic treatments of bovine serum on insulin-like growth factor-I immunoreactivity and binding activity. J. Endocrinol. 127:139-148.
Lee, C. Y., H. P. Lee, J. H. Jeong, K. H. Baik, S. K. Jin, J. H. Lee and S. H. Sohnt. 2002. Effects of restricted feeding, lowenergy diet, and implantation of trenbolone acetate plus estradiol on growth, carcass traits, and circulating concentrations of insulin-like growth factor (IGF)-I and IGFbinding protein-3 in finishing barrows. J. Anim. Sci. 80:84-93.
Liu, J. L. and D. LeRoith. 1999. Insulin-like growth factor I is essential for postnatal growth in response to growth hormone. Endocrinology 140:5178-5184.
McGuinness, M. C. and L. A. Cogburn. 1990. Measurement of developmental changes in plasma insulin-like growth factor-I levels of broiler chicken by radioreceptor assay and radioimmunoassay. Gen. Comp. Endocrinol. 76:446-458.
McGuinness, M. C. and L. A. Cogburn. 1991. Response of young broiler chicken to chronic injection of recombinant-derived human insulin-like growth factor-I. Domest. Anim. Endocrinol. 8:611-620.
McMurtry, J. P., G. L. Francis and Z. Upton. 1997. Insulin-like growth factors in poultry. Domest. Anim. Endocrinol. 14:199-229.
Mitchell, R. D. and W. H. Burke. 1995. Posthatching growth and pectoralis muscle development in broiler strain chickens, bantam chickens and the reciprocal crosses between them. Growth Dev. Aging. 59:149-161
Oudin, A., B. Chevalier, J. Simon and M. J. Duclos. 1998. Muscle insulin-like growth factor-I (IGF-I) receptors in chickens with high or low body weight: effects of age and muscle fibre type. Growth Horm. IGF. Res. 8:243-250.
Pym, R. A., R. J. Johnson, D. B. Etse and P. Eason. 1991. Inheritance of plasma insulin-like growth factor-I and growth rate, food intake, food efficiency and abdominal fatness in chickens. Br. Poult. Sci. 32:285-293.
Radecki, S. V., M. C. Capdevielle, F. C. Buonomo and C. G. Scanes. 1997. Ontogeny of Insulin-like Growth Factors (IGF-I and IGF-II) and IGF-Binding Proteins in the Chicken Following Hatching. Gen. Comp. Endocrinol. 107:109-117.
Rosebrough, R. W., J. P. McMutry and R. Vasilatos-Younken. 1991. Effect of pulsatile or continuous administration of pituitary-derived chicken growth hormone (p-cGH) on lipid metabolism in broiler pullets. Comp. Biochem. Physiol. A. 99:207-214.
Rosselot, G., J. P. McMurtry, R. Vasilatos-Younken and S. Czerwinski. 1995. Effect of exogenous chicken growth hormone (cGH) administration on insulin-like growth factor-I (IGF-I) gene expression in domestic fowl. Mol. Cell. Endocrinol. 114:157-66.
Rotwein, P. 1991. Structure, evolution, expression and regulation of insulin-like growth factors I and II. Growth Factors 5:3-18.
Seo, D. S., J. S. Yun, W. J. Kang, G. J. Jeon, K. C. Hong and Y. Ko. 2001. Association of insulin-like growth factor-I (IGF-I) gene polymorphism with serum IGF-I concentration and body weight in Korean Native Ogol Chicken. Asian-Aust. J. Anim. Sci. 14:915-921.
Simmen, F. A., L. Badinga, M. L. Green, I. Kwak, S. Song and R. C. Simmen. 1998. The porcine insulin-like growth factor system: at the interface of nutrition, growth and reproduction. J. Nutr. 128:315-320.
Spencer, G. S. G., E. Decuypere, J. Buyse and M. Zeman. 1996. Effect of recombinant human insulin-like growth factor-II on weight gain and body composition of broiler chickens. Poult. Sci. 75:388-392.
Tanaka, M., Y. Hayashida, K. Sakaguchi, T. Ohkubo, M. Wakita, S. Hoshino and K. Nakashima. 1996. Growth hormoneindependent expression of insulin-like growth factor I messenger ribonucleic acid in extrahepatic tissues of the chicken. Endocrinology 137:30-34.
Tesseraud, S., R. A. Pym, E. Le Bihan-Duval and M. J. Duclos. 2003. Response of broilers selected on carcass quality to dietary protein supply: live performance, muscle development, and circulating insulin-like growth factors (IGF-I and -II). Poult. Sci. 82:1011-1016.
Tomas, F. M., R. A. Pym, J. P. McMurtry and G. L. Francis. 1998. Insulin-like growth factor (IGF)-I but not IGF-II promotes lean growth and feed efficiency in broiler chickens. Gen. Comp. Endocrinol. 110:262-275.
Vasilatos-Younken, R., X. H. Wang, Y. Zhou, J. R. Day, J. P. McMurty, R. W. Rosebrough, E. Decuypere, N. Buys, V. Darras, J. L. Beard and F. Tomas. 1999. New insights into the mechanism and actions of growth hormone (GH) in poultry. Domest. Anim. Edocrinol. 17:181-190.
Yoon, J., M. S. Rhee, D. S. Seo, B. C. Kim and Y. Ko. 2001. Monitoring of blood cytokines by PIT-1 genotypes in day 150 male pigs. Asian-Aust. J. Anim. Sci. 14:1659-1664.
Yun, J. S., D. S. Seo, M. S. Rhee, S. Oh, B. C. Kim and Y. Ko. 2003a. Relationship of concentrations of endocrine factors at antemortem and postmortem periods to carcass weight and backfat thickness in pigs. Asian-Aust. J. Anim. Sci. 16:335-341.
Yun, J. S., W. J. Kang, D. S. Seo, C. Y. Lee, S. Oh and Y. Ko. 2003b. Relationships of circulating of insuline-like growth factor (IGF)-I and -II to egg production and growth rate in the Korean Native Ogol Chicken. Asian-Aust. J. Anim. Sci. 16:481-488.
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