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NTIS 바로가기Journal of microbiology and biotechnology, v.15 no.1, 2005년, pp.66 - 71
PARK, HEE-SEOP (School of Chemical Engineering and Biotechnology, Inha University) , KANG, SEUNG-HOON (School of Chemical Engineering and Biotechnology, Inha University) , PARK, HYUN-JOO (Song Won Envichem Inc.) , KIM, EUNG-SOO (School of Chemical Engineering and Biotechnology, Inha University)
Doxorubicin is a clinically important anticancer polyketide compound that is typically produced by Streptomyces peucetius var. caesius. To improve doxorubicin productivity by S. peucetius, a doxorubicin pathway-specific regulatory gene, dnrI, was cloned into a high-copy-number plasmid containing a c...
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