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Differential Receptor Targeting of Liver Cells Using $^{99m}Tc-Neoglycosylated$ Human Serum Albumins

Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.31 no.1, 2008년, pp.60 - 66  

Kim, Sung-Eun (Department of Nuclear Medicine, Korea University Hospital) ,  Jeong, Jae-Min (Department of Nuclear Medicine, Seoul National University College of Medicine, Cancer Research Institute, Seoul National University College of Medicine, Institute of Radiation Medicine, Medical Research Center) ,  Hong, Mee-Kyung (Department of Nuclear Medicine, Seoul National University College of Medicine) ,  Jang, Ja-June (Department of Pathology, Seoul National University College of Medicine) ,  Lee, Jae-Tae (Department of Nuclear Medicine, Kyungpook National University Hospital) ,  Lee, Dong-Soo (Department of Nuclear Medicine, Seoul National University College of Medicine, Institute of Radiation Medicine, Medical Research Center) ,  Chung, June-Key (Department of Nuclear Medicine, Seoul National University College of Medicine, Cancer Research Institute, Seoul National University College of Medicine, Institute of Radiation Medicine, Medical Research Center) ,  Lee, Myung-Chul (Department of Nuclear Medicine, Seoul National University College of Medicine, Institute of Radiation Medicine, Medical Research Center)

Abstract AI-Helper 아이콘AI-Helper

Neolactosyl human serum albumin (LSA) targets asialoglycoprotein receptor and shows high liver uptake due to accumulation in hepatocytes. Although neomannosyl human serum albumin (MSA) also shows high liver uptake, it has been reported to be taken up by Kupffer cells and endothelial cells. We compar...

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참고문헌 (34)

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