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생명과학회지 = Journal of life science, v.18 no.5 = no.97, 2008년, pp.738 - 746
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Human immunodeficiency virus (HIV) therapy has been in continuous development since the discovery of HIV. Various RNA genes to inhibit HIV replication have been deployed such as RNA decoy, antisense RNA, ribozyme, as well as conventional drugs that inhibit viral proteins. Small interfering RNAs (siR...
Ambros, Victor. The functions of animal microRNAs. Nature, vol.431, no.7006, 350-355.
An, Dong Sung, Donahue, Robert E., Kamata, Masakazu, Poon, Betty, Metzger, Mark, Mao, Si-Hua, Bonifacino, Aylin, Krouse, Allen E., Darlix, Jean-Luc, Baltimore, David, Qin, F. Xiao-Feng, Chen, Irvin S. Y.. Stable reduction of CCR5 by RNAi through hematopoietic stem cell transplant in non-human primates. Proceedings of the National Academy of Sciences of the United States of America, vol.104, no.32, 13110-13115.
An, Dong Sung, Qin, F. Xiao-Feng, Auyeung, Vincent C., Mao, Si Hua, Kung, Sam K.P., Baltimore, David, Chen, Irvin S.Y.. Optimization and Functional Effects of Stable Short Hairpin RNA Expression in Primary Human Lymphocytes via Lentiviral Vectors. Molecular therapy : the journal of the American Society of Gene Therapy, vol.14, no.4, 494-504.
Anderson, Joseph, Akkina, Ramesh. CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection. Retrovirology, vol.2, 53-53.
Balog, Katalin, Minarovits, J.. NEF: A Pleiotropic Modulator of Primate Lentivirus Infectivity and Pathogenesis. Acta microbiologica et immunologica Hungarica, vol.53, no.1, 51-75.
Barichievy, Samantha, Saayman, Sheena, von Eije, Karin J., Morris, Kevin V., Arbuthnot, Patrick, Weinberg, Marc S.. The Inhibitory Efficacy of RNA POL III-Expressed Long Hairpin RNAs Targeted to Untranslated Regions of the HIV-1 5′ Long Terminal Repeat. Oligonucleotides, vol.17, no.4, 419-432.
Barnor, Jacob Samson, Miyano-Kurosaki, Naoko, Yamaguchi, Kazuya, Abumi, Yusuke, Ishikawa, Koichi, Yamamoto, Naoki, Takaku, Hiroshi. Lentiviral-Mediated Delivery of Combined HIV-1 Decoy TAR and Vif siRNA as a Single 1RNA Molecule that Cleaves to Inhibit HIV-1 in Transduced Cells. Nucleosides, nucleotides & nucleic acids, vol.24, no.5, 431-434.
10.4161/rna.2.2.2044
Bartel, David P. MicroRNAs : Genomics, Biogenesis, Mechanism, and Function. Cell, vol.116, no.2, 281-297.
Beard, Brian C., Keyser, Kirsten A., Trobridge, Grant D., Peterson, Laura J., Miller, Daniel G., Jacobs, Michael, Kaul, Rajinder, Kiem, Hans-Peter. Unique Integration Profiles in a Canine Model of Long-Term Repopulating Cells Transduced with Gammaretrovirus, Lentivirus, or Foamy Virus. Human gene therapy, vol.18, no.5, 423-434.
Bernstein, Emily, Caudy, Amy A., Hammond, Scott M., Hannon, Gregory J.. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature, vol.409, no.6818, 363-366.
Blankson, Joel N., Persaud, Deborah, Siliciano, Robert F.. THE CHALLENGE OF VIRAL RESERVOIRS IN HIV-1 INFECTION. Annual review of medicine, vol.53, 557-593.
10.1128/JVI.77.21.11531-11535.2003
Boden, Daniel, Pusch, Oliver, Silbermann, Rebecca, Lee, Fred, Tucker, Lynne, Ramratnam, Bharat. Enhanced gene silencing of HIV‐1 specific siRNA using microRNA designed hairpins. Nucleic acids research, vol.32, no.3, 1154-1158.
Boneva, Roumiana S., Switzer, William M., Spira, Thomas J., Bhullar, Vinod B., Shanmugam, Vedapuri, Cong, Mian-Er, Lam, Lee, Heneine, Walid, Folks, Thomas M., Chapman, Louisa E.. Clinical and Virological Characterization of Persistent Human Infection with Simian Foamy Viruses. AIDS research and human retroviruses, vol.23, no.11, 1330-1337.
Carmell, Michelle A., Zhang, Liqun, Conklin, Douglas S., Hannon, Gregory J., Rosenquist, Thomas A.. Germline transmission of RNAi in mice. Nature structural biology, vol.10, no.2, 91-92.
Castanotto, Daniela, Sakurai, Kumi, Lingeman, Robert, Li, Haitang, Shively, Louise, Aagaard, Lars, Soifer, Harris, Gatignol, Anne, Riggs, Arthur, Rossi, John J.. Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC. Nucleic acids research, vol.35, no.15, 5154-5164.
Caudy, Amy A., Myers, Mike, Hannon, Gregory J., Hammond, Scott M.. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes & development, vol.16, no.19, 2491-2496.
Cave, Eleanor, Weinberg, Marc S., Cilliers, Tonie, Carmona, Sergio, Morris, Lynn, Arbuthnot, Patrick. Silencing of HIV-1 Subtype C Primary Isolates by Expressed Small Hairpin RNAs Targeted togag. AIDS research and human retroviruses, vol.22, no.5, 401-410.
Chang, L-J, Liu, X, He, J. Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1. Gene therapy, vol.12, no.14, 1133-1144.
10.1128/JVI.76.18.9225-9231.2002
10.1128/JVI.78.5.2601-2605.2004
Dean, Michael, Carrington, Mary, Winkler, Cheryl, Huttley, Gavin A., Smith, Michael W., Allikmets, Rando, Goedert, James J., Buchbinder, Susan P., Vittinghoff, Eric, Gomperts, Edward, Donfield, Sharyne, Vlahov, David, Kaslow, Richard, Saah, Alfred, Rinaldo, Charles, Detels, Roger, O'Brien, Stephen J.. Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene. Science, vol.273, no.5283, 1856-1862.
10.1038/sj.gt.3300780
Gao, Yong, Lobritz, Michael A., Roth, Justin, Abreha, Measho, Nelson, Kenneth N., Nankya, Immaculate, Moore-Dudley, Dawn M., Abraha, Awet, Gerson, Stanton L., Arts, Eric J.. Targets of Small Interfering RNA Restriction during Human Immunodeficiency Virus Type 1 Replication. Journal of virology, vol.82, no.6, 2938-2951.
Grimm, Dirk, Streetz, Konrad L., Jopling, Catherine L., Storm, Theresa A., Pandey, Kusum, Davis, Corrine R., Marion, Patricia, Salazar, Felix, Kay, Mark A.. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature, vol.441, no.7092, 537-541.
Gu, Shuo, Ji, Jianfei, Kim, James D., Yee, Jiing-Kuan, Rossi, John J.. Inhibition of Infectious Human Immunodeficiency Virus Type 1 Virions via Lentiviral Vector Encoded Short Antisense RNAs. Oligonucleotides, vol.16, no.4, 287-295.
Hacein-Bey-Abina, S., Von Kalle, C., Schmidt, M., McCormack, M. P., Wulffraat, N., Leboulch, P., Lim, A., Osborne, C. S., Pawliuk, R., Morillon, E., Sorensen, R., Forster, A., Fraser, P., Cohen, J. I., de Saint Basile, G., Alexander, I., Wintergerst, U., Frebourg, T., Aurias, A., Stoppa-Lyonnet, D., Romana, S., Radford-Weiss, I., Gross, F., Valensi, F., Delabesse, E., Macintyre, E., Sigaux, F., Soulier, J., Leiva, L. E., Wissler, M., Prinz, C., Rabbitts, T. H., Le Deist, F., Fischer, A., Cavazzana-Calvo, M.. LMO2-Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1. Science, vol.302, no.5644, 415-419.
Hacker, Caroline V., Vink, Conrad A., Wardell, Theresa W., Lee, Sheena, Treasure, Peter, Kingsman, Susan M., Mitrophanous, Kyriacos A., Miskin, James E.. The integration profile of EIAV-based vectors. Molecular therapy : the journal of the American Society of Gene Therapy, vol.14, no.4, 536-545.
Hammond, Scott M., Bernstein, Emily, Beach, David, Hannon, Gregory J.. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, vol.404, no.6775, 293-296.
Hayafune, Masaaki, Miyano-Kurosaki, Naoko, Takaku, Hiroshi, Park, Wee-Sung. Silencing of HIV-1 Gene Expression by Sirnas in Transduced Cells. Nucleosides, nucleotides & nucleic acids, vol.25, no.7, 795-799.
Ikeda, T., Shibata, J., Yoshimura, K., Koito, A., Matsushita, S.. Recurrent HIV-1 Integration at the BACH2 Locus in Resting CD4+ T Cell Populations during Effective Highly Active Antiretroviral Therapy. The Journal of infectious diseases : official publication of the Infectious Diseases Society of America, vol.195, no.5, 716-725.
10.4161/rna.2.3.2045
Jacque, Jean-Marc, Triques, Karine, Stevenson, Mario. Modulation of HIV-1 replication by RNA interference. Nature, vol.418, no.6896, 435-438.
Konstantinova, P, de Vries, W, Haasnoot, J, ter Brake, O, de Haan, P, Berkhout, B. Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA. Gene therapy, vol.13, no.19, 1403-1413.
Lai, Eric C.. Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nature genetics, vol.30, no.4, 363-364.
Lassen, Kara, Han, Yefei, Zhou, Yan, Siliciano, Janet, Siliciano, Robert F.. The multifactorial nature of HIV-1 latency. Trends in molecular medicine, vol.10, no.11, 525-531.
Laufs, Stephanie, Guenechea, Guillermo, Gonzalez-Murillo, Africa, Zsuzsanna Nagy, K., Luz Lozano, M., del Val, Coral, Jonnakuty, Sunitha, Hotz-Wagenblatt, Agnes, Jens Zeller, W., Bueren, Juan A., Fruehauf, Stefan. Lentiviral vector integration sites in human NOD/SCID repopulating cells. The journal of gene medicine, vol.8, no.10, 1197-1207.
Lee, Yoontae, Ahn, Chiyoung, Han, Jinju, Choi, Hyounjeong, Kim, Jaekwang, Yim, Jeongbin, Lee, Junho, Provost, Patrick, Rådmark, Olof, Kim, Sunyoung, Kim, V. Narry. The nuclear RNase III Drosha initiates microRNA processing. Nature, vol.425, no.6956, 415-419.
Lehrman, Ginger, Hogue, Ian B, Palmer, Sarah, Jennings, Cheryl, Spina, Celsa A, Wiegand, Ann, Landay, Alan L, Coombs, Robert W, Richman, Douglas D, Mellors, John W, Coffin, John M, Bosch, Ronald J, Margolis, David M. Depletion of latent HIV-1 infection in vivo: a proof-of-concept study. The Lancet, vol.366, no.9485, 549-555.
Leonard, J N, Schaffer, D V. Antiviral RNAi therapy: emerging approaches for hitting a moving target. Gene therapy, vol.13, no.6, 532-540.
LI, MINGJIE, LI, HAITANG, ROSSI, JOHN J.. RNAi in Combination with a Ribozyme and TAR Decoy for Treatment of HIV Infection in Hematopoietic Cell Gene Therapy. Annals of the New York Academy of Sciences, vol.1082, no.1, 172-179.
Li, Ming-Jie, Bauer, Gerhard, Michienzi, Alessandro, Yee, Jiing-Kuan, Lee, Nan-Sook, Kim, James, Li, Shirley, Castanotto, Daniela, Zaia, John, Rossi, John J. Inhibition of HIV-1 infection by lentiviral vectors expressing pol III-promoted anti-HIV RNAs. Molecular therapy : the journal of the American Society of Gene Therapy, vol.8, no.2, 196-206.
Li, Ming-Jie, Kim, James, Li, Shirley, Zaia, John, Yee, Jiing-Kuan, Anderson, Joseph, Akkina, Ramesh, Rossi, John J.. Long-Term Inhibition of HIV-1 Infection in Primary Hematopoietic Cells by Lentiviral Vector Delivery of a Triple Combination of Anti-HIV shRNA, Anti-CCR5 Ribozyme, and a Nucleolar-Localizing TAR Decoy. Molecular therapy : the journal of the American Society of Gene Therapy, vol.12, no.5, 900-909.
Linial, Maxine. Why aren’t foamy viruses pathogenic?. Trends in microbiology, vol.8, no.6, 284-289.
Liu, Xiang, Jiang, Feng, Kalidas, Savitha, Smith, Dean, Liu, Qinghua. Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes. RNA, vol.12, no.8, 1514-1520.
Lo, H-L, Chang, T, Yam, P, Marcovecchio, P M, Li, S, Zaia, J A, Yee, J-K. Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters. Gene therapy, vol.14, no.21, 1503-1512.
Lu, Xiaobin, Yu, Qiao, Binder, Gwendolyn K., Chen, Ziping, Slepushkina, Tatiana, Rossi, John, Dropulic, Boro. Antisense-Mediated Inhibition of Human Immunodeficiency Virus (HIV) Replication by Use of an HIV Type 1-Based Vector Results in Severely Attenuated Mutants Incapable of Developing Resistance. Journal of virology, vol.78, no.13, 7079-7088.
Lund, Elsebet, Güttinger, Stephan, Calado, Angelo, Dahlberg, James E., Kutay, Ulrike. Nuclear Export of MicroRNA Precursors. Science, vol.303, no.5654, 95-98.
Mautino, Mario R., Morgan, Richard A.. Enhanced Inhibition of Human Immunodeficiency Virus Type 1 Replication by Novel Lentiviral Vectors Expressing Human Immunodeficiency Virus Type 1 Envelope Antisense RNA. Human gene therapy, vol.13, no.9, 1027-1037.
Medin, Jeffrey A., Karlsson, Stefan. Viral vectors for gene therapy of hematopoietic cells. Immunotechnology, vol.3, no.1, 3-19.
Mergia, Ayalew, Chari, Soumya, Kolson, Dennis L., Goodenow, Maureen M., Ciccarone, Tina. The Efficiency of Simian Foamy Virus Vector Type-1 (SFV-1) in Nondividing Cells and in Human PBLs. Virology, vol.280, no.2, 243-252.
Mergia, A., Luciw, P.A.. Replication and regulation of primate foamy viruses. Virology, vol.184, no.2, 475-482.
Miyagishi, M, Taira, K. U6 promoter–driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nature biotechnology, vol.20, no.5, 497-500.
10.4161/rna.2.1.1198
Myslinski, Evelyne, Amé, Jean-Christophe, Krol, Alain, Carbon, Philippe. An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene. Nucleic acids research, vol.29, no.12, 2502-2509.
10.1099/vir.0.81554-0
Park, Jeonghae, Nadeau, Peter, Zucali, James R., Johnson, Calvin M., Mergia, Ayalew. Inhibition of simian immunodeficiency virus by foamy virus vectors expressing siRNAs. Virology, vol.343, no.2, 275-282.
Park, W-S, Hayafune, M, Miyano-Kurosaki, N, Takaku, H. Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells. Gene therapy, vol.10, no.24, 2046-2050.
Peng, Y., Lu, J.X., Shen, X.F.. shRNA driven by Pol II/T7 dual-promoter system effectively induce cell-specific RNA interference in mammalian cells. Biochemical and biophysical research communications, vol.360, no.2, 496-500.
Rao, Manjeet K, Wilkinson, Miles F. Tissue-specific and cell type–specific RNA interference in vivo. Nature protocols, vol.1, no.3, 1494-1501.
Rivas, Fabiola V, Tolia, Niraj H, Song, Ji-Joon, Aragon, Juan P, Liu, Jidong, Hannon, Gregory J, Joshua-Tor, Leemor. Purified Argonaute2 and an siRNA form recombinant human RISC. Nature structural & molecular biology, vol.12, no.4, 340-349.
10.2144/05384RN01
Rossi, John J, June, Carl H, Kohn, Donald B. Genetic therapies against HIV. Nature biotechnology, vol.25, no.12, 1444-1454.
Samson, M., Labbe, O., Mollereau, C., Vassart, G., Parmentier, M.. Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor Gene. Biochemistry, vol.35, no.11, 3362-3367.
10.1038/sj.mt.6300298
10.4161/cc.6.4.3807
Schröder, Astrid R.W., Shinn, Paul, Chen, Huaming, Berry, Charles, Ecker, Joseph R., Bushman, Frederic. HIV-1 Integration in the Human Genome Favors Active Genes and Local Hotspots. Cell, vol.110, no.4, 521-529.
Sui, Guangchao, Soohoo, Christina, Affar, El Bachir, Gay, Frédérique, Shi, Yujiang, Forrester, William C., Shi, Yang. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, vol.99, no.8, 5515-5520.
Taylor, Jason A, Vojtech, Lucia, Bahner, Ingrid, Kohn, Donald B, Laer, Dorothee Von, Russell, David W, Richard, Robert E. Foamy Virus Vectors Expressing Anti-HIV Transgenes Efficiently Block HIV-1 Replication. Molecular therapy : the journal of the American Society of Gene Therapy, vol.16, no.1, 46-51.
ter Brake, Olivier, Konstantinova, Pavlina, Ceylan, Mustafa, Berkhout, Ben. Silencing of HIV-1 with RNA Interference: a Multiple shRNA Approach. Molecular therapy : the journal of the American Society of Gene Therapy, vol.14, no.6, 883-892.
Trobridge, Grant D., Miller, Daniel G., Jacobs, Michael A., Allen, James M., Kiem, Hans-Peter, Kaul, Rajinder, Russell, David W.. Foamy virus vector integration sites in normal human cells. Proceedings of the National Academy of Sciences of the United States of America, vol.103, no.5, 1498-1503.
Unwalla, Hoshang J., Li, Hai-Tang, Bahner, Ingrid, Li, Ming-Jie, Kohn, Donald, Rossi, John J.. Novel Pol II Fusion Promoter Directs Human Immunodeficiency Virus Type 1-Inducible Coexpression of a Short Hairpin RNA and Protein. Journal of virology, vol.80, no.4, 1863-1873.
Unwalla, Hoshang J, Li, Ming-Jie, Kim, James D, Li, Hai Tang, Ehsani, Ali, Alluin, Jessica, Rossi, John J. Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA. Nature biotechnology, vol.22, no.12, 1573-1578.
Volpe, Tom, Schramke, Vera, Hamilton, Georgina L., White, Sharon A., Teng, Grace, Martienssen, Robert A., Allshire, Robin C.. RNA interference is required for normal centromere function infission yeast. Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, vol.11, no.2, 137-146.
Volpe, Thomas A., Kidner, Catherine, Hall, Ira M., Teng, Grace, Grewal, Shiv I. S., Martienssen, Robert A.. Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi. Science, vol.297, no.5588, 1833-1837.
Wassenegger, Michael. The Role of the RNAi Machinery in Heterochromatin Formation. Cell, vol.122, no.1, 13-16.
10.1186/1742-4690-3-57
Wu, Xiaolin, Li, Yuan, Crise, Bruce, Burgess, Shawn M.. Transcription Start Regions in the Human Genome Are Favored Targets for MLV Integration. Science, vol.300, no.5626, 1749-1751.
Yi, Rui, Qin, Yi, Macara, Ian G., Cullen, Bryan R.. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & development, vol.17, no.24, 3011-3016.
10.1261/rna.2780503
Zeng, Yan, Wagner, Eric J, Cullen, Bryan R. Both Natural and Designed Micro RNAs Can Inhibit the Expression of Cognate mRNAs When Expressed in Human Cells. Molecular cell, vol.9, no.6, 1327-1333.
Zhou, N, Fang, J, Mukhtar, M, Acheampong, E, Pomerantz, R J. Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. Gene therapy, vol.11, no.23, 1703-1712.
Zucali, James R., Ciccarone, Tina, Kelley, Vicky, Park, Jeonghae, Johnson, Calvin M., Mergia, Ayalew. Transduction of Umbilical Cord Blood CD34+ NOD/SCID-Repopulating Cells by Simian Foamy Virus Type 1 (SFV-1) Vector. Virology, vol.302, no.2, 229-235.
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