This study was investigated that quality inspection of distributed Scutellariae Radix in Korea. To evaluate the quality of these herbal medicines, we carried out TLC pattern, foreign matter in purity, loss on drying, ash, acid-insoluble ash, oil content, dilute ethanol-soluble, water-soluble, ether-...
This study was investigated that quality inspection of distributed Scutellariae Radix in Korea. To evaluate the quality of these herbal medicines, we carried out TLC pattern, foreign matter in purity, loss on drying, ash, acid-insoluble ash, oil content, dilute ethanol-soluble, water-soluble, ether-soluble extracts contents, quantitative analyses, residual $SO_2$, individual heavy metals and organochlorine pesticides. To measure contents of baicalin, baicalein and wogonin, we were quantitative analyzed using HPLC. The average contents of baicalin, baicalein and wogonin were detected by 13.28 (${\pm}$0.43)%, 1.17 (${\pm}$0.04)% and 0.40 (${\pm}$0.02)%, respectively. Each average contents As, Cd, Hg and Pb was 0.059 (${\pm}$0.054) mg ${\cdot}$$kg^{-1}$, 0.019 (${\pm}$0.010) mg ${\cdot}$$kg^{-1}$, 0.017 (${\pm}$0.057) ppm and 0.242 (${\pm}$0.084) mg ${\cdot}$$kg^{-1}$, respectively.
This study was investigated that quality inspection of distributed Scutellariae Radix in Korea. To evaluate the quality of these herbal medicines, we carried out TLC pattern, foreign matter in purity, loss on drying, ash, acid-insoluble ash, oil content, dilute ethanol-soluble, water-soluble, ether-soluble extracts contents, quantitative analyses, residual $SO_2$, individual heavy metals and organochlorine pesticides. To measure contents of baicalin, baicalein and wogonin, we were quantitative analyzed using HPLC. The average contents of baicalin, baicalein and wogonin were detected by 13.28 (${\pm}$0.43)%, 1.17 (${\pm}$0.04)% and 0.40 (${\pm}$0.02)%, respectively. Each average contents As, Cd, Hg and Pb was 0.059 (${\pm}$0.054) mg ${\cdot}$$kg^{-1}$, 0.019 (${\pm}$0.010) mg ${\cdot}$$kg^{-1}$, 0.017 (${\pm}$0.057) ppm and 0.242 (${\pm}$0.084) mg ${\cdot}$$kg^{-1}$, respectively.
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제안 방법
The purpose of this study was tried to the simultaneous determination of distributed Scutellariae Radix compounds, i.e., baicalin, baicalein and wogonin by HPLC. Monitoring of hazard materials for distributed herbal medicines were experimented on residual SO2, individual heavy metals (As, Cd, Hg, Pb) and residual pesticides.
대상 데이터
16 samples of commercial Scutellariae Radix were collected in Seoul, Daegu, Gwangju and Jecheon, Korea and identified by H. J. Kim in Wbosuk University. A voucher specimen (No.
Analyses were performed on a Luna C18 analytical column (4.6 × 250 mm 5 ㎛, Phenomenex). Mobile phase was a mixture of acetonitrile: 1.
성능/효과
All samples were in exceeded of 10% i.e. contents of sum for baicalin, baicalein and wogonin were more than 10%. The result of safety test, each one sample was not satisfied with residual SO2 and content of Hg, respectively.
94%, respectively. As result of research, All of samples contents were more than 0.6% for baicalein and all of samples were more than 0.2% for wogonin. For previously research, average contents of baicalin, baicalein and wogonin were about 24.
These components could be indicated and represented efficacy for Scutellariae Radix. Result of this study, sum of the contents for baicalin, baicalein and wogonin should be suitable fdr standard limit i.e. more than 10.0% (Table 1).
참고문헌 (13)
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