참고문헌 (14)

1. Buynak, J. D. : The discovery and development of modified penicillin- and cephalosporin-derived $\beta$ -lactamase inhibitors. Current Medicinal Chemistry 11, 1951 (2004) 

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2. Hanaki, H., Yamazaki, H., Harada, H., Kubo, R., Kobayashi, T., Atsuda, K. and Sunakawa, K. : The synthesis of 7-substituted- 3-dinitrostyryl cephalosporins and their ability for detecting extended spectrum $\beta$ -lactamases. Journal of Antibiotics 58, 69 (2005) 

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3. Reading, C. and Farmer, T. : The inhibition of $\beta$ -lactamases from gram-negative bacteria by clavulanic acid. Biochem. J. 199, 779 (1981) 

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4. Hunter, P. A., Cloeman, K. J. and Taylor, D. : In vitro synergistic properties of clavulanic acid with ampicillin, amoxicillin, ticarcillin. J. Antimicrob. Chemther. 6, 455 (1980) 

   

5. English, A. R., Retsema, J. A., Girard, A. E., Lynch, J. E. and Barth, W. E. : CP-45,899, $\beta$ -lactamase inhibitor that extends the antibacterial spectrum of $\beta$ -lactams : Initial bacteriological characterization. Antimicrob. Agents Chemother. 14, 414 (1978) 

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6. Micetich, R. G., Maiti, S. N., Spevak, P., Hall, T. W., Yamabe, S., Ishida, N., Tanaka, M., Yamazaki, T., Nakai, A. and Ogawa, K. : Synthesis and $\beta$ -lactamase inhibitory properties of 2 $\beta$ -[(1,2,3- triazol-1-yl)methyl]-2 $\alpha$ -methylpenam-3 $\alpha$ -carboxylic acid 1,1- dioxide and related triazolyl derivatives. J. Med. Chem. 30, 1469 (1987) 

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7. De A. F., Attorrese, G., Cavicchio, G., Ciampa, S., Di, T. A., Fattori, D., Nicoletti, R. and Domenici, E. : Synthesis and preliminary biological evaluation of 3'-substituted cephem sulfones as potential $\beta$ -lactamase inhibitors. Euro. J. Org. Chem. 16, 3075 (2001) 

8. Buynak, J. D. and Chen, H. : Cephalosporin-derived mercaptans as inhibitors of serine and metallo $\beta$ -lactamases. U.S. Pat. 2006178357 A1 20060810 (2006) 

9. Buynak, J. D., Vogeti, L., Doppalapudi, V. R., Solomon, G. M. and Chen, H. : Cephalosporin-derived inhibitors of $\beta$ - Lactamase. Part 4: The C3 substituent. Bioorg. Med. Chem. Letters 12, 1663 (2002) 

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10. Buynak, J. D., Doppalapudi, V. R., Rao, A. S., Nidamarthy, S. D. and Adam, G. : The synthesis and evaluation of 2-substituted- 7-(alkylidene) cephalosporin sulfones as $\beta$ -lactamase inhibitors. Bioorg. Med. Chem. Letters 10, 847 (2000) 

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11. Mansour, T. S. and Venkatesan, A. M. : Bicyclic 6-alkylidenepenems as class-D $\beta$ -lactamase inhibitors. U.S. Pat. 2005686347 20050601 (2006) 

12. Venkatesan, A. M., Mansour, T. S., Abe, T., Mihira, A., Agarwal, A., Ushirogochi, H., Gu, Y., Tamai, S. and Sum, F. W. : Preparation of heterotricyclic 6-alkylidene-penems as $\beta$ - lactamase inhibitors for use against bacterial infections or diseases. U.S. Pat. 2002377051 20020501 (2003) 

13. John, D. B., Kuangcong, W., Brian, B., Diphti, K., Ling, H., Hanh, K. N. and Christa, L. C. : Synthesis and biological activity of 7-alkylidene cephems. J. Med. Chem. 38, 1022 (1995) 

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14. John, E. G., Michael, D. C., Subramanian, N. and Mark, H. S. : Nucleophilic Sn2 displacement on penicillin 6- and cephalosporin-7-triflate; 6 $\beta$ -Iodopenicillanic acid. A new $\beta$ - lactamase inhibitor. Tetrahedron Letter, 21, 2991 (1980) 

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