Chaskar, Atul
(Department of chemistry, Post graduate and Research Centre, C. K. Thakur College)
,
Padalkar, Vikas
(Department of chemistry, Post graduate and Research Centre, C. K. Thakur College)
,
Phatangare, Kiran
(Department of chemistry, Post graduate and Research Centre, C. K. Thakur College)
,
Langi, Bhushan
(Department of chemistry, Post graduate and Research Centre, C. K. Thakur College)
,
Naik, Pallavi
(Department of chemistry, Post graduate and Research Centre, C. K. Thakur College)
A series of quinoxaline derivatives were efficiently synthesized in excellent yield using phosphomolybdic acid as a catalyst. The advantages of present methods are ambient reaction temperature, simplicity of operation, high atom economy, recyclability of HPA catalyst and ecofriendly nature of reacti...
A series of quinoxaline derivatives were efficiently synthesized in excellent yield using phosphomolybdic acid as a catalyst. The advantages of present methods are ambient reaction temperature, simplicity of operation, high atom economy, recyclability of HPA catalyst and ecofriendly nature of reaction medium.
A series of quinoxaline derivatives were efficiently synthesized in excellent yield using phosphomolybdic acid as a catalyst. The advantages of present methods are ambient reaction temperature, simplicity of operation, high atom economy, recyclability of HPA catalyst and ecofriendly nature of reaction medium.
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제안 방법
Due to the keggin structure of phosphomolybdic acid the first and second protons dissociates completely and accelerate the rate of reaction. Keeping all these results inview, we decidedto generalize the protocol by treatingvarious 1,2-diketones with 1,2-benzenediamines in presence of phosphomolybdic acid. Quinoxaline synthesis of all the substrate was observed in 72 to 89%yield.
성능/효과
From this study it was found that phosphomolybdic acid was superior to all other catalysts examined and gave good atom economy. Due to the keggin structure of phosphomolybdic acid the first and second protons dissociates completely and accelerate the rate of reaction.
In conclusion, we have developed a simple, convenient and efficient method forsynthesis ofquinoxaline and its derivativesfromvarious 1,2-diketones and 1,2-benzenediamines using safe, stable and easily available phosphomolybdic acid as a solid acid catalyst. The advantages ofthis procedure are simplicity of operation, short reaction time, high atom economy, recyclability of catalyst, and ecofriendly nature.
참고문헌 (42)
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