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Abstract AI-Helper 아이콘AI-Helper

Purpose: Full-mouth disinfection enables to reduce the probability of cross contamination from untreated pockets to treated ones, for completing the entire SRP under local anesthesia with chlorhexidine as a mouth wash in two visits within 24 hours. This study aimed to compare the clinical effects of...

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제안 방법

  • A questionnaire was given to the patients after one week of treatment in the upper right quadrant to determine if there were any adverse effects after treatment. In the experimental group, one patient reported an increase in body temperature and three patients with a prior medical history reported herpes labialis.
  • Adverse effects, such as an increase in body temperature, and herpes labialis were determined from a questionnaire given one week after the procedure in the upper right quadrant.
  • Although the additional effects of chlorhexidine use cannot be excluded, a full-mouth root planing (Frp) group, which carried out SRP without using chlorhexidine within 24 hours, was excluded from this experiment in order to compare the effect. A previous study reported no significant clinical and microbiological difference between Frp and Fdis but early stage healing i.
  • The control group, after one week of supragingival scaling, received subgingival S RP by quadrants with one week intervals under local anesthesia using curettesand ultrasonic instrument. For both groups, tooth brushing instruction and oral prophylaxis were carried out at the baseline, three months and six months after the upper right quadrant SRP.
  • 1% chlorhexidine solution were performed within three times for 10 minutes. Over a two week period after the procedure, the patients were instructed to perform a pharynx-rinse twice daily for 30 seconds. In order to improve the cooperation, the patients were encouraged to record the daily mouth-washing time.
  • USA) was used for statistical analysis. Repeated measures ANOVA was used to determine the changes in the clinical studies in 1, 3 and 6 months for each group. A t-test was used for the group difference in the changes at a specific point (1, 3, 6-month) if the measured values showed a normal distribution.
  • The clinical indices were measured one week after S RP, before subgingival S RP (baseline), and at one month, three months and six months after Fdis or cSRP at the upper right quadrant. Considering the accessibility of repeated measurement, the sulcus bleeding index (SBI), gingival recession (GR), probing depth (PD) and clinical attachment level (CAL) were measured at 6 sites in each tooth of the upper right quadrant.
  • In order to improve the cooperation, the patients were encouraged to record the daily mouth-washing time. The control group, after one week of supragingival scaling, received subgingival S RP by quadrants with one week intervals under local anesthesia using curettesand ultrasonic instrument. For both groups, tooth brushing instruction and oral prophylaxis were carried out at the baseline, three months and six months after the upper right quadrant SRP.
  • One week later, the patients were divided into the control and experimental group according to their preferences and received treatment as follows. The experimental group received a modified protocol of Quirynen et al.6); 30 seconds of mouth-rinsing with a 0.1% chlorhexidine solution (Hexamedin, Bukwang, Seoul, Korea) before the procedure and an additional 10 seconds of pharynx-rinsing by bending the neck backward to hold the solution in the pharyngeal area. The patients were instructed to brush the dorsal surface of their tongues for 60 seconds.
  • They called it full-mouth disinfection6). The method consists of 1-minute brushing of the dorsal surface of the tongue with a chlorhexidine gel (1%), 1-minute mouth irrigation with a chlorhexidine solution (0.2%) with pharynx in contact with the solution for the last 10 seconds of the rinse. After the completion of each SRP, all pockets should be irrigated subgingivally with a chlorhexidine gel (1%) three times within 10 minutes with the irrigation being repeated after one week.
  • After the completion of each SRP, all pockets should be irrigated subgingivally with a chlorhexidine gel (1%) three times within 10 minutes with the irrigation being repeated after one week. The patient is instructed to mouth-wash with 10ml of a chlorhexidine solution (0.2%) twice daily for 1 minute over a 2-week period.
  • In this study, supragingival full-mouth scaling was administered in advance. The subgingival treatment was performed one week after scaling while c S RP was carried out by quadrant at one-week intervals. Fdis showed significant improvement compared with cS RP.
  • 2%) are not available in Korea. Therefore, in this study of generalized moderate to severe chronic periodontitis patients, a chlorhexidine solution (0.1%), which can be purchased over-the-counter and has few side-effects, was used in the modified Fdis that was designed to be simple to apply after SRP. In addition, the clinical effects of Fdis were compared with the conventional SRP over a 6-month period.
  • This study compared the clinical effects of modified Fdis after scaling using a chlorhexidine solution (0.1%) with those of conventional SRP in the treatment of moderate to severe generalized chronic periodontitis after a 6 month follow-up. After Fdis for the treatment of moderate to severe generalized chronic periodontitis, there was a reduction of gingival inflammation, plaque level, and probing depth, a smaller increase in gingival recession, and attachment gain in the teeth with an initial pocket depth of a moderate level (4~6 mm) and multi-roots, and larger attachment gain in the proximal surface compared with the bucco-lingual surface.
  • This study compared the clinical effects of modified Fdis after scaling using a chlorhexidine solution (0.1%) with those of conventional SRP in the treatment of moderate to severe generalized chronic periodontitis for 6 months.

대상 데이터

  • Among the patients at the department of periodontology, Chonnam National University Hospital, those who satisfied the conditions below were included in the experiment.
  • Overall, 42 sites per patient were measured. The plaque index (PI) was measured at 4 sites in each tooth of the upper right quadrant including the bucco-lingual and mesio-distal surfaces, making 28 sites per patient.

데이터처리

  • Repeated measures ANOVA was used to determine the changes in the clinical studies in 1, 3 and 6 months for each group. A t-test was used for the group difference in the changes at a specific point (1, 3, 6-month) if the measured values showed a normal distribution. A Mann-Whitney inspection was used if the values showed an abnormal distribution.
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참고문헌 (29)

  1. Quirynen M, De Soete M, Dierickx K, Van Steenberghe D. The intra-oral translocation of periodontopathogens jeopardises the outcome of periodontal therapy. A review of the literature. J Clin Periodontol 2001;28:499-507 

  2. Bollen CML, Mongardini C, Papaioannou W, Van Steenberghe D, Quirynen M. The effect of a one-stage full-mouth disinfection on different intra-oral niches. Clinical and microbiological observations. J Clin Periodontol 1998;25:56-66 

  3. Cobb CM. Non-surgical pocket therapy. Annals Periodontol 1996;1:443-490 

  4. Goodson JM, Tanner A, McArdle S, Dix K, Watanabe SM. Multicenterevaluation of tetracycline fiber therapy. III. Microbiological response. J Periodontal Res 1991;26:440-451 

  5. Harper DS, Robinson PJ. Correlation of histometric, microbial, and clinical indicators of periodontal disease status before and after root planing. J Clin Periodontol 1987;14:190-196 

  6. Quirynen M, Bollen CML, Vandekerckhove BNA et al. Full- versus partial-mouth disinfection in the treatment of periodontal infections: short-term clinical and microbiological observations. J Periodontal Res 1995;74:1459-1467 

  7. Quirynen M, Mongardini C, De Soete M et al. The role of chlohexidine in the one-stage full-mouth disinfection treatment of patients with advanced adult periodontitis. Long-term clinical and microbiological observations. J Clin Periodontol 2000;27:578-589 

  8. Bollen CML, Vandekerckhove BNA, Papaioannou W, Van Eldere J, Quirynen M. Full- versus partial-mouth disinfection in the treatment of periodontal infections. A pilot study: long-term microbiological observations. J Clin Periodontol 1996;23:960-970 

  9. Mongardini C, Van Steenberghe D, Dekeyser C, Quirynen M. One stage full- versus partial-mouth disinfection in the treatment of chronic adult or early-onset periodontitis. I. Long-term clinical observations. J Clin Periodontol 1999;70:632-645 

  10. Cho IH, Jung UW, Cha JH et al. Clinical evaluation of full mouth disinfection therapy. J Korean Acad Periodontol 2005;35(3):597-608 

  11. Apatzidou DA, Kinane DF. Quadrant root planing versus same-day full-mouth root planing. J Clin Periodontol 2004;31:152-159 

  12. Koshy G, Kawashima Y, Kiji M et al. I.Effects of single- visit full-mouth ultrasonic debridement versus quadrant-wise ultrasonic debridement. J Clin Periodontol 2005;32:734-743 

  13. WennstrOm JL, Tomasi C, Bertelle A, Dellaseg E. Full-mouth ultrasonic debridement versus quadrant scaling and root planing as an initial approach in the treatment of chronic periodontitis. J Clin Periodontol 2005;32:851-859 

  14. KnOfler GU, Purschwitz RE, Jentsch HFR. Clinical evaluation of partial- and full-mouth scaling in the treatment of chronic periodontitis. J Periodontol 2007;11:2135-2142 

  15. Moreira RM, Feres-Filho EJ. Comparison between full-mouth scaling and root planing and quadrant-wise basic therapy of aggressive periodontitis: 6-month clinical results. J Periodontol 2007;9:1683-1688 

  16. Armitage GC. Development of a classification system for periodontal diseases and conditions. Annals Periodontol 1999;4:1-6 

  17. Muhlemann HR, Son S. Gingival sulcus bleeding- a leading symptom in initial gingivitis. Helvetica Odontologica Acta 1971;15:107-113 

  18. Silness P, LOe H. Periodontal disease in pregnancy. Acta Odontologica Scandinavica 1964;22:121-127 

  19. Van Winkelhoff AJ, Van der Velden U,De Graaff J. Microbial succession in recolonising deep periodontal pockets after a single course of supra- and subgingival debridement. J Clin Periodontol 1988;15:116-122 

  20. Papaioannou W, Bollen CML, Van Eldere J, Quirynen M. The adherence of periodontopathogens to periodontal probes. A possible factor in intra-oral transmissions? J Periodontol 1996;67:1164-1169 

  21. Loesche WJ, Svanberg ML, Pape HR. Intra-oral transmission of Streptococcus mutans by a dental explorer. J Periodontal Res 1979;58:1765-1770 

  22. Preus HR, Lassen J, Ass A, Christersson LA.Prevention of transperiodontal sites during subgingival application of antibiotics. J Clin Periodontol 1993;20:299-303 

  23. Lee SH, Kim OS, Kim YJ, Chung HJ. Clinical short-term effects of full-mouth disinfection. J Korean Acad Periodontol 2007;37(3):613-624 

  24. Danser MM, Van Winkelhoff AJ, De Graaff J, Loos BG, Van der Velden U. Short-term effect of full-mouth extraction on periodontal pathogens colonising the oral mucous membranes. J Clin Periodontol 1994;21:484-489 

  25. Aguillon JC, Ferreira V, Nunez E et al. Immunomodulation of LPS ability to induce the local Schwartzman reaction. Scandinavian J Immunol 1996;44:551-555 

  26. Jervoe-Storm PM, Semaan E, AlAhdab H et al. Clinical outcomes of quadrant root planing versus full-mouth root planing. J Clin Periodontol 2006;33:209-215 

  27. Vandekerckhove BNA, Bollen CML, Dekeyser C, Darius P, Quirynen M. Full- versus partial-mouth disinfection in the treatment of periodontal infection. Long-term clinical observations. J Periodontol 1996;67:1251-1259 

  28. Quirynen M, Teughels W, Van Steenberghe D. Impact of antiseptics on one-stage, full-mouth disinfection. Letter to the editor. J Clin Periodontol 2006;33:49-52 

  29. Gomi K, Yashim A, Nagano T et al. Effects of full-mouth and root planing in conjunction with systemically administered azithromycin. J Periodontol 2007;3:422-429 

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