Purpose: The objective of this clinical presentation was to present a clinical case series report of socket preservation, sinus augmentation, and bone grafting using a horse-derived biomaterial. Methods: A horse-derived biomaterial was used in 8 patients for different indications including socket pr...
Purpose: The objective of this clinical presentation was to present a clinical case series report of socket preservation, sinus augmentation, and bone grafting using a horse-derived biomaterial. Methods: A horse-derived biomaterial was used in 8 patients for different indications including socket preservation following tooth extraction, osseous bone grafting, and sinus augementation procedures. Surgeries were performed by a well trained specialist and clinical radiographs were obtained at designated intervals. Biopsy cores of 2 ${\times}$ 8 mm prior to implant placement was obtained following a healing interval of 4 - 6 months. A clinical and histologic evaluation was performed to evaluate the clinical effectiveness and biocompatibility of the biomaterial. Results: All surgeries in 8 patients were successful with uneventful healing except for one case with membrane exposure that eventually resulted with a positive outcome. Radiographic display of the healing phase during different intervals showed increased radiopacity of granular nature as the healing time increased. No signs of adverse effect or infection was observed clinically and the tissues surrounding the biomaterial seemed well-tolerated with good intentional healing. The augmented sinuses healed uneventfully suggesting in part, good biocompatibility of the biomaterial. Dental implants placed following socket preservation were inserted with high initial torque suggesting good initial stability and bone quality. Conclusions: Our results show that at least on a tentative level, a horse-derived biomaterial may be used clinically in socket preservation, sinus augmentation, bone grafting techniques with good intentional healing and positive results.
Purpose: The objective of this clinical presentation was to present a clinical case series report of socket preservation, sinus augmentation, and bone grafting using a horse-derived biomaterial. Methods: A horse-derived biomaterial was used in 8 patients for different indications including socket preservation following tooth extraction, osseous bone grafting, and sinus augementation procedures. Surgeries were performed by a well trained specialist and clinical radiographs were obtained at designated intervals. Biopsy cores of 2 ${\times}$ 8 mm prior to implant placement was obtained following a healing interval of 4 - 6 months. A clinical and histologic evaluation was performed to evaluate the clinical effectiveness and biocompatibility of the biomaterial. Results: All surgeries in 8 patients were successful with uneventful healing except for one case with membrane exposure that eventually resulted with a positive outcome. Radiographic display of the healing phase during different intervals showed increased radiopacity of granular nature as the healing time increased. No signs of adverse effect or infection was observed clinically and the tissues surrounding the biomaterial seemed well-tolerated with good intentional healing. The augmented sinuses healed uneventfully suggesting in part, good biocompatibility of the biomaterial. Dental implants placed following socket preservation were inserted with high initial torque suggesting good initial stability and bone quality. Conclusions: Our results show that at least on a tentative level, a horse-derived biomaterial may be used clinically in socket preservation, sinus augmentation, bone grafting techniques with good intentional healing and positive results.
* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.
문제 정의
A need for a complete disease transmission free donor has propagated research and development of a bone replacement graft from sources other than bovine origin. The objective of this clinical report was to observe both clinically and histologically, the biocompatibility and physical properties of a horse-derived bone biomaterial.
대상 데이터
A horse-derived biomaterial was used in 8 patients admitted to Seoul National University, Department of Periodontology for different indications including socket preservation following tooth extraction, osseous bone grafting, and sinus augmentation procedure. Surgeries were performed by a well trained specialist.
성능/효과
Our results show that at least on a tentative level, a horse-derived biomaterial may be used clinically in socket preservation, sinus augmentation, bone grafting techniques with good intentional healing and positive results.
참고문헌 (20)
Jensen SS, Aaboe M, Pinholt EM. Tissue reaction and material characteristics of four bone substitutes. Int J oral Maxillofacial Implant 1966;11:55-66
Artzi Z, Tal H, Dayan D. Porous bovine bone mineral in healing of human extraction sockets:Histochemical observations at 9 months J Periodontol 2001;72:152-159
Wenz B, Oesch B, Horst M. Analysis of the risk of transmitting bovine spongiform encephalopathy through bone grafts derived from bovine bone. Biomaterials 2001;22:1599-1606
Yukna RA, Mayer ET, Brite DV. Longitudinal evaluation of durapatite ceramic as an alloplastic implant in periodontal defects after 3 years. J Periodontol 1984;55:633-637
Meffert RM, Thomas JR, Hamilton KM, Brownstein CN. Hydroxyapatite as an alloplastic graft in the treatment of human periodontalosseous defects. J Periodontol 1985;56:63-73
Klinglsberg J. Scleral allograft in the repair of periodontal osseous defects. NY state Dent J 1972;38:418-420
Klinge B, Alberius P, Isaksson S, Jonsson AJ. Osseous response to implanted natural bone mineral and synthetic hydroxylapatite ceramic in the repair of experimental skull bone defects. J oral maxillofac Surg 1992;50:241-249
Young C, Sandstedt P, Skoglund A. A comparative study of anoganic xenogenic bone and autogenous bone implants for bone regeneration in rabbits. Int J oral Maxillofacial Implant 1999;14:72-76
Skoglund A, Hising P, Young C. A Clinical and histologic examination in humans of the osseous response to implanted natural bone mineral. Int J oral Maxillofacial Implant 1997;12:194-199
Becker W, Clokie C, Sennerby L, Urist MR, Becker BE. Histologic findings after implantation and evaluation of different grafting materials and titanium micro screws into extraction sockets: case reports. J Periodontol 1998;68:414-421
Goldberg VM, Stevenson S. Natural history of autografts and allografts. Clin Orthop Related Res 1987;225:7-15
Burchardt H. The biology of bone graft repair. Clin Orthop 1983;174:28-32
Brown P, Preece MA, Will RG. 'Friendly fire' in medicine: hormones, homografts, and Creutzfeldt-Jakob disease in the UK. Lancet 1992;340:24-27
Shin-Il Yeo, Sung-Hwan Park, Woo-chang Noh et al. A comparative analysis of basic characteristics of several deproteinized bovine bone substitutes. J Korean Acad Periodontol 2009;39:149-156
Artzi Z, Tal H, Dayan D. Porous bovine bone mineral in healing of human extraction sockets. Part Ⅰ: histomorphometric evaluations at 9 months. J Periodontol 2000;71:1015-1023
AI-Helper
※ AI-Helper는 부적절한 답변을 할 수 있습니다.