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Abstract AI-Helper 아이콘AI-Helper

Paeoniflorin (PF), a monoterpene glucoside, is a primary bioactive component of paeony, the root extract of Paeonia lactiflora. We tested the antioxidant effects of PF and its ability to prevent lipopolysaccharide (LPS)-induced oxidative stress. We intraperitoneally administered PF (2.5, 5, or 10 mg...

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참고문헌 (55)

  1. Nature A. Aderem 406 782 2000 10.1038/35021228 Aderem, A. and Ulevitch, R. J., Toll-like receptors in the induction of the innate immune response. Nature, 406, 782-787 (2000). 

  2. Meth. Enzymol. H. Aebi 105 121 1984 10.1016/S0076-6879(84)05016-3 Aebi, H., A Catalase in vitro. Meth. Enzymol., 105, 121-126 (1984). 

  3. Biol. Pharm. Bull. Y. Aniya 28 19 2005 10.1248/bpb.28.19 Aniya, Y., Koyama, T., Miyagi, C., Miyahira, M., Inomata, C., Kinoshita, S., and Ichiba, T., Free radical scavenging and hepatoprotective actions of the medicinal herb, Crassocephalum crepidioides from the Okinawa Islands. Biol. Pharm. Bull., 28, 19-23 (2005). 

  4. J. Leukoc. Biol. A. P. Bautista 48 123 1990 10.1002/jlb.48.2.123 Bautista, A. P., Meszaros, K., Bojta, J., and Spitzer, J. J., Superoxide anion generation in the liver during the early stage of endotoxemia in rats. J. Leukoc. Biol., 48, 123-128 (1990). 

  5. Anal. Biochem. C. Beauchamp 44 276 1971 10.1016/0003-2697(71)90370-8 Beauchamp, C. and Fridovich, I., Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal. Biochem., 44, 276-287 (1971). 

  6. Immunology B. Beutler 3 169 2003 Beutler, B. and Rietschel, E. T., Innate immune sensing and its roots: the story of endotoxin. Immunology, 3, 169-176 (2003). 

  7. Mech. Ageing Dev. D. A. Butterfield 122 945 2001 10.1016/S0047-6374(01)00249-4 Butterfield, D. A. and Kanski, J., Brain protein oxidation in agerelated neurodegenerative disorders that are associated with aggregated proteins. Mech. Ageing Dev., 122, 945-962 (2001). 

  8. Jpn. J. Pharmacol. K. Dezaki 69 281 1996 10.1254/jjp.69.281 Dezaki, K., Kimura, I., Miyahara, K., and Kimura, M., Complementary effects of paeoniflorin and glycyrrhizin on intracellular Ca2+ mobilization in the nerve-stimulated skeletal muscle of mice. Jpn. J. Pharmacol., 69, 281-284 (1996). 

  9. Curr. Opin. Cell Biol. T. Finkel 10 248 1998 10.1016/S0955-0674(98)80147-6 Finkel, T., Oxygen radicals and signaling. Curr. Opin. Cell Biol., 10, 248-253 (1998). 

  10. Acc. Chem. Res. I. Fridovich 5 321 1972 10.1021/ar50058a001 Fridovich, I., Superoxide radical and superoxide dismutase. Acc. Chem. Res., 5, 321-323 (1972). 

  11. Am. J. Clin. Pathol. C. S. Frings 53 89 1970 10.1093/ajcp/53.1.89 Frings, C. S. and Dunn, R. T., A colorimetric method for determination of total serum lipid based on the sulfuricphospho-vanillin reaction. Am. J. Clin. Pathol., 53, 89-92 (1970). 

  12. Biol. Pharm. Bull. B. J. Ha 29 1305 2006 10.1248/bpb.29.1305 Ha, B. J., Lee, S. H., Kim, H. J., and Lee, J. Y., The role of salicornia herbacea in ovariectomy-induced oxidative stress. Biol. Pharm. Bull., 29, 1305-1309 (2006). 

  13. Cent. Nerv. Syst. Trauma. E. D. Hall 3 281 1986 10.1089/cns.1986.3.281 Hall, E. D. and Braughler, J. R., Role of lipid peroxidation in post-traumatic spinal cord degeneration: a review. Cent. Nerv. Syst. Trauma., 3, 281-294 (1986). 

  14. Am. J. Physiol. A. Hassid 267 1040 1994 Hassid, A., Arabshahi, H., Bourcier, T., Dhaunsi, G.S. and Matthews, C., Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells. Am. J. Physiol., 267, 1040-1048 (1994). 

  15. Science J. A. Hoffmann 284 1313 1999 10.1126/science.284.5418.1313 Hoffmann, J. A., Kafatos, F. C., Janeway, C. A., and Ezekowitz, R. A., Phylogenetic perspectives in innate immunity. Science, 284, 1313-1317 (1999). 

  16. Planta Med. F. L. Hsu 63 323 1997 10.1055/s-2006-957692 Hsu, F. L., Lai, C. W., and Cheng, J. T., Antihyperglycemic effects of paeoniflorin and 8-debenzoylpaeoniflorin, glucosides from the root of Paeonia lactiflora. Planta Med., 63, 323-325 (1997). 

  17. Biochem. J. P. Jones 110 621 1968 10.1042/bj1100621 Jones, P. and Suggett, A., The catalase-hydrogen peroxide system. A theoretical appraisal of the mechanism of catalase action. Biochem. J., 110, 621-629 (1968). 

  18. J. Agric. Food Chem. E. S. Kao 53 430 2005 10.1021/jf040231f Kao, E. S., Wang, C. J., Lin, W. L., Yin, Y. F., Wang, C. P., and Tseng, T. H., Anti-inflammatory potential of flavonoid contents from dried fruit of Crataegus pinnatifida in vitro and in vivo. J. Agric. Food Chem., 53, 430-436 (2005). 

  19. Jpn. J. Pharmacol. M. Kimura 41 263 1986 10.1254/jjp.41.263 Kimura, M., Kimura, I., Muroi, M., Nakamura, T., and Shibata, S., Depolarizing effects of glycyrrhizin-derivatives relating to the blend effects with paeoniflorin in mouse diaphragm muscle. Jpn. J. Pharmacol., 41, 263-265 (1986). 

  20. Xenobiotica B. Ketterer 16 957 1986 10.3109/00498258609038976 Ketterer, B., Detoxification reactions of glutathione and glutathione reductase. Xenobiotica, 16, 957-975 (1986). 

  21. J. Pharmacol. Exp. Ther. H. Kono 307 74 2003 10.1124/jpet.103.053595 Kono, H., Asakawa, M., Fujii, H., Maki, A., Amemiya, H., Yamamoto, M., Matsuda, M., and Matsumoto, Y., Edaravone, A novel free radical scavenger, prevents liver injury and mortality in rats administered endotoxin. J. Pharmacol. Exp. Ther., 307, 74-82 (2003). 

  22. J. Immunol. V. Lakics 161 2490 1998 10.4049/jimmunol.161.5.2490 Lakics, V. and Vogel, S. N., Lipopolysaccharide and ceramide use divergent signaling pathways to induce cell death in murine macrophages. J. Immunol., 161, 2490-2500 (1998). 

  23. Biochem. Biophys. Res. Commun. R. A. Lawrence 71 952 1976 10.1016/0006-291X(76)90747-6 Lawrence, R. A. and Burk, R. F., Glutathione peroxidase activity in selenium-deficient rat liver. Biochem. Biophys. Res. Commun., 71, 952-958 (1976). 

  24. Am. J. Pathol. E. Levy 51 269 1967 Levy, E. and Ruebner, B. H., Hepatic changes produced by a single dose of endotoxin in the mouse. Light microscopy and histochemistry. Am. J. Pathol., 51, 269-285 (1967). 

  25. Eur. J. Pharmacol. J. Liang 183 901 1990 10.1016/0014-2999(90)92731-W Liang, J., Zhou, A., Chen, M., and Xu, S., Negatively regulatory effects of paeoniflorin on immune cells. Eur. J. Pharmacol., 183, 901-902 (1990). 

  26. Pharmacol. Res. H. K. Lim 5 471 2000 10.1006/phrs.2000.0730 Lim, H. K., Kim, H. S., Choi, H. S., Oh, S., Jang, C. G., Choi, J., Kim, S. H., and Chang, M. J., Effects of acetylbergenin against d-galactosamine induced hepatotoxicity in rats. Pharmacol. Res., 5, 471-474 (2000). 

  27. Toxicol. In Vitro C. F. Lima 18 457 2004 10.1016/j.tiv.2004.01.001 Lima, C. F., Carvalho, F., Fernandes, E., Bastos, M. L., Santos-Gomes, P. C., Fermandes-Ferreira, M., and Pereira-Wilson, C., Evaluation of toxic/protective effects of the essential oil of Salvia officinalis on freshly isolated rat hepatocytes. Toxicol. In Vitro, 18, 457-465 (2004). 

  28. J. Biol. Chem. O. H. Lowry 193 265 1951 10.1016/S0021-9258(19)52451-6 Lowry, O. H. and Rosenbrough, N. J., Protein measurement with folin reagent. J. Biol. Chem., 193, 265-275 (1951). 

  29. FASEB J. L. J. Machlin 1 441 1987 10.1096/fasebj.1.6.3315807 Machlin, L. J. and Bendich, A., Free radical tissue damage: protective role of antioxidant nutrients. FASEB J., 1, 441-445 (1987). 

  30. Bioorg. Med. Chem. Lett. H. Matsuda 8 2939 1998 10.1016/S0960-894X(98)00528-9 Matsuda, H., Ishikado, A., Nishida, N., Ninomiya, K., Fujiwara, H., Kobayashi, Y., and Yoshikawa, M., Hepatoprotective, superoxide scavenging, and antioxidative activities of aromatic constituents from the bark of Betula platyphylla var. japonica. Bioorg. Med. Chem. Lett., 8, 2939-2944 (1998). 

  31. J. Ethnopharmacol. S. K. Mitra 63 181 1998 10.1016/S0378-8741(98)00088-9 Mitra, S. K., Venkataranganna, M. V., Sundaram, R., and Gopumadhavan, S., Protective effect of HD-03, a herbal formulation, against various hepatotoxic agents in rats. J. Ethnopharmacol., 63, 181-186 (1998). 

  32. Pharmacol. Rev. S. Moncada 43 109 1991 Moncada, S., Palmer, R. M., and Higgs, E. A., Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev., 43, 109-142 (1991). 

  33. Pharmacol. Biochem. Behav. H. Ohta 45 719 1993 10.1016/0091-3057(93)90530-7 Ohta, H., Ni, J. W., Matsumoto, K., Watanabe, H., and Shimizu, M., Peony and its major constituent, paeoniflorin, improve radial maze performance impaired by scopolamine in rats. Pharmacol. Biochem. Behav., 45, 719-723 (1993). 

  34. J. Med. Food L. Pari 5 171 2002 10.1089/10966200260398206 Pari, L. and Ashod, K. N., Hepatoprotective activity of moringuoleifera on antitubercular drug induced liver damage in rats. J. Med. Food, 5, 171-177 (2002). 

  35. Pharmacol. Res. L. Pari 49 481 2004 10.1016/j.phrs.2003.11.005 Pari, L. and Marugan, P., Protective role of tetrahydrocur cumin against erythromycin estolate-induced hepatotoxicity. Pharmacol. Res., 49, 481-486 (2004). 

  36. Food Sci. Biotechnol. J. Y. Park 16 205 2007 Park, J. Y., Park, C. M., Kim, J. J., Noh, K. H., Cho, C. W., and Song, Y. S., The protective effect of chlorophyll a aginst oxidative stress and inflammatory processes in LPS-stimulated macrophages. Food Sci. Biotechnol., 16,205-211 (2007). 

  37. J. Hepatol. O. Peter 35 187 2001 10.1016/S0168-8278(01)00103-9 Peter, O., Marjolijn, T. M., Marina, H. J., Frans, D., Barbro, N. M., Han, M., Maarten, J. H. S., Dirk, K. F. M., Klaas, P., and Geny, M. M. G., Rat liver slices as a tool to study LPS-induced inflammatory response in the liver. J. Hepatol., 35, 187-194 (2001). 

  38. Kidney Int. H. D. Rupprecht 57 70 2000 10.1046/j.1523-1755.2000.00828.x Rupprecht, H. D., Akagi, Y., Keil, A., and Hofer, G., Nitric oxide inhibits growth of glomerular mesangial cells: role of the transcription factor EGR-1. Kidney Int., 57, 70-82 (2000). 

  39. Biopharm. Drug Dispos. R. Sallie 12 251 1997 10.1002/bdd.2510120403 Sallie, R., Tredger, J. M., and William, R., Drugs and the liver. Biopharm. Drug Dispos., 12, 251-259 (1997). 

  40. Pharmacol. Toxicol. R. Sandhir 74 66 1994 10.1111/j.1600-0773.1994.tb01077.x Sandhir, R., Julka, D., and Gill, K. D., Lipoperoxidative damage on lead exposure in rat brain and its implicationa on membrane bound enzymes. Pharmacol. Toxicol., 74, 66-71 (1994). 

  41. Biochem. Biophys. Res. Commun. H. H. Schmidt 181 1372 1991 10.1016/0006-291X(91)92090-7 Schmidt, H. H. and Murad, F., Purification and characterization of a human NO synthase. Biochem. Biophys. Res. Commun., 181, 1372-1377 (1991). 

  42. Immunology Y. Shoji 84 543 1995 Shoji, Y., Uedono, Y., Ishikura, H., Takeyama, N., and Tanaka, T., DNA damage induced by tumour necrosis factor-alpha in L929 cells is mediated by mitochondrial oxygen radical formation. Immunology, 84, 543-548 (1995). 

  43. J. Exp. Med. D. J. Stuehr 169 1543 1989 10.1084/jem.169.5.1543 Stuehr, D. J. and Nathan, C. F., Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cell. J. Exp. Med., 169, 1543-1555 (1989). 

  44. Surgery K. Sugino 101 746 1987 Sugino, K., Dohi, K., Yamada, K., and Kawasaki, T., The role of lipid peroxidation in endotoxin-induced hepatic damage and the protective effect of antioxidants. Surgery, 101, 746-752 (1987). 

  45. J. Pharmacobio-dyn. E. Sugishita 7 427 1984 10.1248/bpb1978.7.427 Sugishita, E., Amagaya, S., and Ogihara, Y., Studies on the combination of Glycyrrhizae Radix in Shakuyakukanzo-To. J. Pharmacobio-dyn., 7, 427-435 (1984). 

  46. Yakugaku Zasshi K. Takagi 89 879 1969 10.1248/yakushi1947.89.7_879 Takagi, K. and Harada, M., Pharmacological studies on herb paeony root. Central effects of paeoniflorin, and combined effects with licorice component FM100. Yakugaku Zasshi, 89, 879-886 (1969). 

  47. Am. J. Obstet. Gynecol. T. Tamaya 155 1134 1986 10.1016/0002-9378(86)90365-0 Tamaya, T., Sato, S., and Okada, H. H., Possible mechanism of steroid action of the plant herb extracts glycyrrhizin, glycyrrhetinic acid, and paeoniflorin: Inhibition by plant herb extracts of steroid protein binding in the rabbit. Am. J. Obstet. Gynecol., 155, 1134-1139 (1986). 

  48. J. Cell. Biochem. H. Tsuboi 93 162 2004 10.1002/jcb.20134 Tsuboi, H., Hossain, K., Akhand, A. A., Takeda, K., and Du, J, R. M., Paeoniflorin induces apoptosis of lymphocytes through a redoxlinked mechanism. J. Cell. Biochem., 93, 162-172 (2004). 

  49. J. Ethnopharmacol. R. Vilwanathan 101 55 2005 10.1016/j.jep.2005.03.019 Vilwanathan, R. and Kanchi, S. S., Thiruvengadam, Devaki., Hepatoprotective activity of Tridax procumbens against d-galactosamine/lipopolysaccharide induced hepatitis in rats. J. Ethnopharmacol., 101, 55-60 (2005). 

  50. J. Ethnopharmacol. P. J. Wills 108 320 2006 10.1016/j.jep.2006.05.032 Wills, P. J. and Asha, V. V., Protective effect of Lygodium flexuosum (L.) Sw. extract against carbon tetrachlorideinduced acute liver injury in rats. J. Ethnopharmacol., 108, 320-326 (2006). 

  51. Yakugaku Zasshi J. Yamahara 102 881 1982 10.1248/yakushi1947.102.9_881 Yamahara, J., Yamada, T., Kimura, H., Sawada, T., and Fujimura, H., Biologically active principles of crude drugs: Antiallergic principles of “shoseiryu-to”: Effect on delayedtype allergy reaction. Yakugaku Zasshi, 102, 881-886 (1982). 

  52. Cell Stress Chaperones D. Yan 9 378 2004 10.1379/CSC-51R.1 Yan, D., Saito, K., Ohmi, Y., Fujie, N., and Ohtsuka, K., Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones, 9, 378-389 (2004). 

  53. Biochem. Biophys. Res. Commun. H. J. Yoon 358 954 2007 10.1016/j.bbrc.2007.05.042 Yoon, H. J., Moon, M. E., Park, H. S., Im, S. Y., and Kim, Y. H., Chitosan oligosaccharide (COS) inhibits LPS-induced inflammatory effects in RAW 264.7 macrophage cells. Biochem. Biophys. Res. Commun., 358, 954-959 (2007). 

  54. Toxicology M. I. Yousef 199 47 2004 10.1016/j.tox.2004.02.014 Yousef, M. I., Aluminium-induced changes in hematobiochemical parameters, lipid peroxidation and enzyme activities of male rabbits: protective role of ascorbic acid. Toxicology, 199, 47-57 (2004). 

  55. Toxicology M. I. Yousef 227 240 2006 10.1016/j.tox.2006.08.008 Yousef, M. I., Awad, T. I., and Mohamed, E. H., Deltamethrin-induced oxidative damage and biochemical alterations in rats and its attenuation by vitamin E. Toxicology, 227, 240-247 (2006). 

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