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Glycemic Index of Insu 100® Herbal Preparation Containing Korean Red Ginseng, Carob, Mulberry, and Banaba 원문보기

Journal of ginseng research = 高麗人參學會誌, v.34 no.2, 2010년, pp.89 - 92  

Son, Dong-Wook (Korea Ginseng Corporation) ,  Lee, Jong-Won (Korea Ginseng Corporation) ,  Lee, Pyeong-Jae (Department of Natural Medicine Resources, Semyung University) ,  Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)

Abstract ▼ AI-Helper 아이콘AI-Helper

In this study, we determined the glycemic index (GI) of an herbal preparation (Insu $100^{(R)}$; Korean red ginseng, carob, mulberry, and banaba). Ten subjects (men and women) took part in standard glycemic testing during a 4-week study period (with duplicate trials of each treatment). In...

주제어

#Glucose   #Glycemic index   #Insu $100^{(R)}$  

AI 본문요약
AI-Helper 아이콘 AI-Helper

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제안 방법

  • The herbal preparation was composed of Korean red ginseng, carob, mulberry, and banaba extract. The 10 subjects consumed portions of the herbal preparation and the reference food (Glucodin1 glucose powder; Boots Healthcare, Australia), each containing 50 g of available carbohydrate, on separate mornings over a 4-week period. The reference food was consumed at the first and last test sessions of the study.

대상 데이터

  • In compliance with these guidelines, Insu 100® was made in liquid form. It contained 7% crude saponin derived from 6-year old Korean red ginseng, 25% pinitol derived from carob, 60% total solids obtained from mulberry, and 1% corosolic acid derived from banaba. This study was carried out after approval by the Institute Review Board of Inje University Hospital and was conducted in accordance with the Declaration of Helsinki.
  • Ten healthy volunteers (5 males: average age, 25.4 years; 5 females: average age, 26.4 years) were recruited from Inje University Hospital. Volunteers were excluded from the study if they had a body mass index greater than 23, were taking medication or related products, had diabetes, were pregnant, suspected to be pregnant, or were breastfeeding, had a history of allergies to medicine, or were found to be generally unsuitable by the physicians in charge of the study.

데이터처리

  • 5 (Table 3). The between-assessment reproducibility of the average AUC after intake of the reference food or the herbal preparation was evaluated by calculating coefficients of variation (CV). These were 4.

이론/모형

  • AUC values were calculated using the incremental method (Graphpad ver. 4.0, Prism Software, San Diego, CA, USA). Paired t-tests were used to compare subject data with baseline and to compare peak blood glucose values and areas under the plotted glycemic response curves.
  • The incremental AUC was calculated according to the trapezoidal (Simpson’s) rule using the area above the baseline (fasting glucose).
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참고문헌 (15)

  1. Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr 1981;34:362-366. 

    상세보기 crossref

  2. Jenkins DJ, Wolever TM, Jenkins AL, Josse RG, Wong GS. The glycaemic response to carbohydrate foods. Lancet1984;2:388-391. 

  3. Wolever TM, Jenkins DJ, Jenkins AL, Josse RG. The glycemic index: methodology and clinical implications. Am J Clin Nutr 1991;54:846-854. 

    상세보기 crossref

  4. Brand-Miller J, Wolever TM, Foster-Powell K, Colagiuri S. The new glucose revolution: the authoritative guide to the glycemic index. New York: Marlowe & Co., 2003. 

  5. Ludwig DS. Dietary glycemic index and obesity. J Nutr 2000;130:280S-283S. 

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  6. Miller JC. Importance of glycemic index in diabetes. Am J Clin Nutr 1994;59:747S-752S. 

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  7. Jenkins DJ, Jenkins AL. Nutrition principles and diabetes. A role for “lente carbohydrate”? Diabetes Care 1995;18:1491-1498. 

    상세보기 crossref

  8. Wolever TM, Jenkins DJ, Vuksan V, Jenkins AL, Wong GS, Josse RG. Beneficial effect of low-glycemic index diet in overweight NIDDM subjects. Diabetes Care 1992;15:562-564. 

    상세보기 crossref

  9. Park KS, Lee DE, Sung JH, Chung SH. Comparisons of antidiabetic effect of Panax ginseng on MLD STZ induced diabetic rats in terms of time of administration. J Ginseng Res 2002;26:191-195. 

    원문보기 상세보기 crossref

  10. Joo CN, Koo JH, Lee HB. Study on the hypoglycemic action of the fat soluble fraction of Panax ginseng C.A. Meyer in streptozotocin induced diabetic rats. J Ginseng Res 1993;17:13-21. 

  11. Sievenpiper JL, Sung MK, Di Buono M, Seung-Lee K, Nam KY, Arnason JT, Leiter LA, Vuksan V. Korean red ginseng rootlets decrease acute postprandial glycemia: results from sequential preparation- and dose-finding studies.J Am Coll Nutr 2006;25:100-107. 

    상세보기 crossref

  12. Park KS, Ko SK, Chung SH. Comparison of antidiabetic effect between Ginseng Radix Alba, Ginseng Radix Rubra and Panax guinquefolius Radix in MLD STZ-induced diabetic rats. J Ginseng Res 2003;27:56-61. 

  13. Kim MJ, Yoo KH, Kim JH, Seo YT, Ha BW, Kho JH, Shin YG, Chung CH. Effect of pinitol on glucose metabolism and adipocytokines in uncontrolled type 2 diabetes. Diabetes Res Clin Pract 2007;77:S247-S251. 

    상세보기 crossref

  14. Kimura T, Nakagawa K, Kubota H, Kojima Y, Goto Y, Yamagishi K, Oita S, Oikawa S, Miyazawa T. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 2007;14:5869-5874. 

  15. Park MY, Lee KS, Sung MK. Effects of dietary mulberry, Korean red ginseng, and banaba on glucose homeostasis in relation to PPAR-alpha, PPAR-gamma, and LPL mRNA expressions. Life Sci 2005;77:3344-3354. 

    상세보기 crossref

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