최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기KSBB Journal, v.26 no.4, 2011년, pp.333 - 340
유종훈 (수원대학교 화학공학과) , 정인일 (수원대학교 화학공학과) , 이지은 (수원대학교 화학공학과) , 임교빈 (수원대학교 화학공학과)
In this study, gemcitabine-loaded methoxy poly(ethylene glycol)-b-poly(L-lactide) (MPEG-PLLA) microparticles with different PEG block lengths were prepared by a W/O/W double emulsion technique. The present study focuses on the investigation of the influence of various preparative parameters such as ...
Dutt, M. and G. K. Khuller (2001) Sustained release of isoniazid from a single injectable dose of poly (D,L-lactide-co-glycolide) microparticles as a therapeutic approach towards tuberculosis. Int. J. Antimicrob. Agents 17: 115-122.
Amperiadou, A. and M. Georgarakis (1995) Controlled release salbutamol sulphate microcapsules prepared by emulsion solvent-evaporation technique and study on the release affected parameters. Int. J. Pharm. 115: 1-8.
Zhang, P., L. Chen, W. Gu, Z. Xu, Y. Gao, and Y. Li (2007) In vitro and in vivo evaluation of donepezil-sustained release microparticles for the treatment of Alzheimer's disease. Biomater. 28: 1882-1888.
Abdel-Rahman, S. I., G. M. Mahrous, and M. El-Badry (2009) Preparation and comparative evaluation of sustained release metoclopramide hydrochloride matrix tablets. Saudi Pharm. J. 17: 283-288.
Feng, S. S. and S. Chien (2003) Chemotherapeutic engineering: Application and further development of chemical engineering principles for chemotherapy of cancer and other diseases. Chem. Eng. Sci. 58: 4087-4114.
Persidis, A. (1999) Cancer multidrug resistance. Nature Biotech. 17: 94-95.
Yeo, Y., N. Baek, and K. Park (2001) Microencapsulation methods for delivery of protein drugs. Biotechnol. Bioprocess Eng. 6: 213-230.
Park, J. H., M. Ye, and K. Park (2005) Biodegradable polymers for microencapsulation of drugs. Molecules 10: 146-161.
Langer, R. (2006) Biomaterials for drug delivery and tissue engineering. MRS Bull. 31: 477-485
Joo, H. J., I.-I. Jung, G. Lim, and J.-H. Ryu (2011) Production of gemcitabine-loaded poly (L-lactic acid) microparticles using supercritical carbon dioxide: Effect of process parameters. Kor. Soci. Biotechnol. Bioeng. J. 26: 69-77.
Anderson, J. M. and M. S. Shive (1997) Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv. Drug Del. Rev. 28: 5-24.
Jain, R. A. (2000) The manufacturing techniques of various drug loaded biodegradable poly (lactide-co-glycolide) (PLGA) devices. Biomater. 21: 2475-2490.
Qiao, M., D. Chen, X. Ma, and Y. Liu (2005) Injectable biodegradable temperature-responsive PLGA-PEG-PLGAcopolymers: Synthesis and effect of copolymer composition on the drug release from the copolymer-based hydrogels. Int. J. Pharm. 294: 103-112.
Hagan, S. A., A. G. A. Coombes, M. C. Garnett, S. E. Dunn, M. C. Davies, L. Illum, and S. S. Davis (1996) Polylactide-poly (ethylene glycol) copolymers as drug delivery systems: 1. Characterization of water dispersible micelle-forming systems. Langmuir 12: 2153-2161.
Chen, L., Z. Xie, J. Hu, X. Chen, and X. Jing (2007) Enantiomeric PLA-PEG block copolymers and their stereocomplex micelles used as rifampin delivery. J. Nanopart. Res. 9: 777-785.
de Faria, T. J., A. M. de Campos, and E. L. Senna (2005) Preparation and characterization of poly (D,L-lactide) (PLA) and poly (D,L-lactide)-poly (ethylene glycol) (PLA-PEG) nanocapsules containing antitumoral agent methotrexate. Macromol. Symp. 229: 228-233.
Matsushima, A., H. Nishimura, Y. Ashihara, Y. Yakata, and Y. Inada (1980) Modification of E. coli asparaginase with 2,4-bis (o-methoxypoly-ethylene glycol)-6-chloro-s-triazene (activated PEG2); disappearance of binding ability towards anti-serum and retention of enzymatic activity. Chem. Lett. 9:773-776.
Hinds, K. D. and S. W. Kim (2002) Effects of PEG conjugation on insulin properties. Adv. Drug Del. Rev. 54: 505-530.
Tsubery, H., M. Mironchik, M.Fridkin, and Y. Shechter (2004) Prolonging the action of protein and peptide drugs by a novel approach of reversible polyethylene glycol modification. J. Biol. Chem. 279: 38118-38124.
Locher, C., E. Fabre-Guillevin, F. Brunetti, J. Auroux, J. C. Delchier, P. Piedbois, and L. Zelek (2008) Fixed-dose rate gemcitabine in elderly patients with advanced pancreatic cancer: An observational study. Crit. Rev. Oncol. Hematol. 68: 178-182.
Fruscella, E., D. Gallo, G. Ferrandina, G. D'Agostino, and G. Scambia (2003) Gemcitabine: current role and future options in the treatment of ovarian cancer. Crit. Rev. Oncol. Hematol. 48: 81-88.
Wirk, B. and E. Perez (2006) Role of Gemcitabine in Breast Cancer Management: An Update. Semin. Oncol. 33: 6-14.
Pasut, G., F. Canal, L. D. Via, S. Arpicco, F. M. Veronese, and O. Schiavon (2006) Antitumoral activity of PEG-gemcitabine prodrugs targeted by folic acid. J. of Cont. Rel. 127: 239-248.
Celano1, M., M. G. Calvagno, S. Bulotta, D. Paolino, F. Arturi, D. Rotiroti, S. Filetti, M. Fresta, and D. Russo (2004) Cytotoxic effects of Gemcitabine-loaded liposomes in human anaplastic thyroid carcinoma cells. BMC Cancer 4: 1-5.
Gang, J., S.-B. Park, W. C. Hyung, E. H. Choi, J. Wen, H.-S. Kim, Y.-G. Shul, S. J. Haam, and S. Y. Song (2007) Magnetic poly $\varepsilon$ -caprolactone nanoparticles containing $Fe_3O_4$ and gemcitabine enhance anti-tumor effect in pancreatic cancer xenograft mouse model. J. Drug Targeting 15: 445-453.
Lee, S. Y., S. H. Lee, and J. H. Kim (2000) Synthesis and characterization of linear and star-shaped poly (lactic acid) stereo-block copolymers. Polymer (Korea) 24: 638-645.
O'Donnell, P. B. and J. W. McGinity (1997) Preparation of microsphere by the solvent evaporation technique. Adv. Drug Del. Rev. 28: 25-42.
Mokleby, T. (2009) Active loading of gemcitabine into liposomes. Master Thesis. University of Tromso, Tromso, Norway.
Pistel, K.-F. and T. Kissel (2000) Effects of salt addition on the microencapsulation of proteins using W/O/W double emulsion technique. J. Microencapsul. 17: 467-483.
Rosca, I. D., F. Watari, and M. Uo (2004) Microparticle formation and its mechanism in single and double emulsion solvent evaporation. J. Contr. Rel. 99: 271-280.
Wei, Q., W. Wei, R. Tian, L.-Y. Wang, Z.-G. and Sua, G.-H. Ma (2008) Preparation of uniform-sized PELA microspheres with high encapsulation efficiency of antigen by premix membrane emulsification. J. Colloid Interface Sci. 323: 267-273.
Meng, F. T., G. H. Ma, W. Qiu, and Z. G. Su (2003) W/O/W double emulsion technique using ethyl acetate as organic solvent: effect of its diffusion rate on the characteristics of microparticles. J. Control. Rel. 91: 407-416.
Cohen-Sela, E., M. Chorny, N. Koroukhov, H. D. Danenberg, and G. Golomb (2009) A new double emulsion solvent diffusion technique for encapsulating hydrophilic molecules in PLGA nanoparticles. J. Control. Rel. 133: 90-95.
*원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.