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Constituents of Pyrus pyrifolia with Inhibitory Activity on the NO Production and the Expression of iNOS and COX-2 in Macrophages and Microglia 원문보기

Natural product sciences, v.18 no.3, 2012년, pp.183 - 189  

Yoo, Ji-Hye (College of Pharmacy, Sookmyung Women's University) ,  Yang, Ki-Sook (College of Pharmacy, Sookmyung Women's University)

Abstract AI-Helper 아이콘AI-Helper

It is well known that inflammation is associated with neurodegenerative disorders, including Alzheimer' disease, Parkinson's disease and ischemia. Nitric oxide (NO), a pro-inflammatory mediator, is produced by inducible NO synthase (iNOS) in microglia as well as macrophages and appears to account fo...

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  • 01, significantly different from control (LPS alone), analyzed by Student’s t-test. B, All values were significantly different from control (LPS alone).
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