Hafeez, Saima
(The Aga Khan University Hospital)
,
Sufian, Saira
(Liaquat National Hospital)
,
Beg, Madiha
(The Aga Khan University Hospital)
,
Hadi, Quratulain
(The Aga Khan University Hospital)
,
Jamil, Yasir
(The Aga Khan University Hospital)
,
Masroor, Imrana
(The Aga Khan University Hospital)
Background: Ovarian cancer is the second most common malignancy in Pakistani women, accounting for 4% of all cancers in the female population. The aim of this study was to determine sensitivity, specificity, positive and negative predictive values and 95% confidence intervals for ultrasound in chara...
Background: Ovarian cancer is the second most common malignancy in Pakistani women, accounting for 4% of all cancers in the female population. The aim of this study was to determine sensitivity, specificity, positive and negative predictive values and 95% confidence intervals for ultrasound in characterization of ovarian masses in patients presenting at public and private tertiary care hospitals in Karachi, Pakistan. Materials and Methods: We adopted a cross-sectional analytical study design to retrospectively collect data from January 2009-11 from medical records of two tertiary care hospitals. Using a non-probability purposive sampling technique, we recruited a sample of 86 women aged between 15 and 85 years fulfilling inclusion criteria with histopathologically proven ovarian masses presenting for an ultrasound examination in our radiology departments. Results: Our retrospective data depicted sensitivity and specificity of ultrasound to be 90.7%, 95%CI (0.77, 0.97) and 91.4%, 95%CI (0.76, 0.98) respectively. Positive predictive value was 93%, 95%CI (0.79, 0.98) and negative predictive value was 89%, 95%CI (0.73, 0.96). A total of 78 ovarian masses were detected, out of which 42 were malignant and 36 were benign. Conclusions: Results of our study further reinforce the conclusion that ultrasound should be used as an initial modality of choice in the workup of every woman suspected of having an ovarian mass. It not only results in decreasing the mortality but also avoids unnecessary surgical interventions.
Background: Ovarian cancer is the second most common malignancy in Pakistani women, accounting for 4% of all cancers in the female population. The aim of this study was to determine sensitivity, specificity, positive and negative predictive values and 95% confidence intervals for ultrasound in characterization of ovarian masses in patients presenting at public and private tertiary care hospitals in Karachi, Pakistan. Materials and Methods: We adopted a cross-sectional analytical study design to retrospectively collect data from January 2009-11 from medical records of two tertiary care hospitals. Using a non-probability purposive sampling technique, we recruited a sample of 86 women aged between 15 and 85 years fulfilling inclusion criteria with histopathologically proven ovarian masses presenting for an ultrasound examination in our radiology departments. Results: Our retrospective data depicted sensitivity and specificity of ultrasound to be 90.7%, 95%CI (0.77, 0.97) and 91.4%, 95%CI (0.76, 0.98) respectively. Positive predictive value was 93%, 95%CI (0.79, 0.98) and negative predictive value was 89%, 95%CI (0.73, 0.96). A total of 78 ovarian masses were detected, out of which 42 were malignant and 36 were benign. Conclusions: Results of our study further reinforce the conclusion that ultrasound should be used as an initial modality of choice in the workup of every woman suspected of having an ovarian mass. It not only results in decreasing the mortality but also avoids unnecessary surgical interventions.
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제안 방법
Data were collected in structured proforma which elicited information regarding patient’s demographics and ultrasound characteristics of the ovarian mass.
Confidentiality of patients’ records was assured and maintained throughout the study. Ultrasound reports from medical records of patients with proven ovarian mass on histopathology were analyzed. All the ultrasounds were performed on NEMIO XG, TOSHIBA machines by a radiologist having at least 3 years of experience in performing pelvic ultrasounds.
대상 데이터
Ultrasound reports from medical records of patients with proven ovarian mass on histopathology were analyzed. All the ultrasounds were performed on NEMIO XG, TOSHIBA machines by a radiologist having at least 3 years of experience in performing pelvic ultrasounds. Trans abdominal scans were done using 3.
96). Data were collected of 84 women with the diagnosis of ovarian masses over a period of two years from both hospital excluding six such cases for certain specific reasons. Reasons for exclusion were histopathologically inadequate sample in two and nonspecific tissue in others.
성능/효과
00 for the right ovary. Positive predictive value was 93%, 95%CI(0.79, 0.98) and negative predictive value was 89%, 95%CI(0.73, 0.96). Data were collected of 84 women with the diagnosis of ovarian masses over a period of two years from both hospital excluding six such cases for certain specific reasons.
Results gathered from our retrospective data depicted sensitivity and specificity of ultrasound to be 90.7%, 95%CI(0.77, 0.97) and 91.4%, 95%CI(0.76, 0.98) respectively in characterization of benign and malignant ovarian masses. The age range of patients was between 16-86 years with mean age of 40.
In conclusion, this study yielded the diagnostic accuracy of ultrasound to be 91% in the diagnosis of ovarian masses, thus increasing its reliability. Thus ultrasound seems to be an initial modality of choice in the workup of every woman suspected of having an ovarian mass.
후속연구
No comprehensive study has been conducted in the recent past that emphasizes the significance of such a novel and yet effective investigative tool in detection of malignancy which is so fatal. We, therefore studied whether ultrasound is sensitive in characterization of ovarian masses in women (15-85 years) presenting at public and private tertiary care hospitals in Karachi? We hope that results of this study will encourage concerned personnel to expedite specific actions required to teach and train appropriate techniques to those who are routinely carrying out such ultrasounds as early detection and accurate staging will not only improve the disease prognosis but would also help avoiding excessive radiation examinations in those who would neither benefit nor require them.
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