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NTIS 바로가기Journal of ginseng research = 高麗人參學會誌, v.37 no.3, 2013년, pp.293 - 299
Kim, Mi-Yeon (School of Systems Biological Science, Soongsil University) , Cho, Jae Youl (Department of Genetic Engineering, Sungkyunkwan University)
20S-dihydroprotopanaxadiol (2H-PPD) is a derivative of protopanaxadiol, a glycone of ginsenosides prepared from Panax ginseng. Although ginsenosides and acidic polysaccharides are known to be major active ingredients in ginseng, the immunopharmacological activities of their metabolites and derivativ...
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3 Byeon SE Yi YS Oh J Yoo BC Hong S Cho JY The role of Src kinase in macrophage-mediated inflammatory responses. Mediators Inflamm 2012 2012 512926 23209344
4 Cho JY Fox DA Horejsi V Sagawa K Skubitz KM Katz DR Chain B The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation. Blood 2001 98 374 382 10.1182/blood.V98.2.374 11435306
5 Lee YG Lee J Cho JY Cell-permeable ceramides act as novel regulators of U937 cell-cell adhesion mediated by CD29, CD98, and CD147. Immunobiology 2010 215 294 303 10.1016/j.imbio.2009.05.009 19576658
6 Jeannin P Duluc D Delneste Y IL-6 and leukemia-inhibitory factor are involved in the generation of tumor-associated macrophage: regulation by IFN-γ. Immunotherapy 2011 3 4 Suppl 23 26 10.2217/imt.11.30 21524164
7 Hasani-Ranjbar S Nayebi N Larijani B Abdollahi M A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity. World J Gastroenterol 2009 15 3073 3085 10.3748/wjg.15.3073 19575486
9 Hasegawa H Proof of the mysterious efficacy of ginseng: basic and clinical trials: metabolic activation of ginsenoside: deglycosylation by intestinal bacteria and esterification with fatty acid. J Pharmacol Sci 2004 95 153 157 10.1254/jphs.FMJ04001X4 15215638
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15 Chen G Yang X Nong S Yang M Xu B Zhang W Two novel hydroperoxylated products of 20(S)-protopanaxadiol produced by Mucor racemosus and their cytotoxic activities against human prostate cancer cells. Biotechnol Lett 2013 35 439 443 10.1007/s10529-012-1098-x 23183919
16 Zhu GY Li YW Tse AK Hau DK Leung CH Yu ZL Fong WF 20(S)-protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells. Eur J Pharmacol 2011 668 88 98 10.1016/j.ejphar.2011.06.008 21703260
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27 Lee YG Kim JY Lee JY Byeon SE Hong EK Lee J Rhee MH Park HJ Cho JY Regulatory effects of Codonopsis lanceolata on macrophage-mediated immune responses. J Ethnopharmacol 2007 112 180 188 10.1016/j.jep.2007.02.026 17418512
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32 Kim JY Lee YG Kim MY Byeon SE Rhee MH Park J Katz DR Chain BM Cho JY Src-mediated regulation of inflammatory responses by actin polymerization. Biochem Pharmacol 2010 79 431 443 10.1016/j.bcp.2009.09.016 19769947
33 Kim BH Cho JY Regulatory role of ginsenoside Rp1, a novel ginsenoside derivative, on CD29-mediated cell adhesion. Planta Med 2009 75 316 320 10.1055/s-0028-1112213 19165715
34 Cho JY Katz DR Chain BM Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation. Br J Pharmacol 2003 140 269 276 10.1038/sj.bjp.0705436 12970105
35 Cho JY Chain BM Vives J Horejsi V Katz DR Regulation of CD43-induced U937 homotypic aggregation. Exp Cell Res 2003 290 155 167 10.1016/S0014-4827(03)00322-7 14516796
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