선택한 단어 수는 입니다.
최소 단어 이상 선택하여야 합니다.
최소 단어 이상 선택하여야 합니다.
선택한 단어 수는 30입니다.
최대 10 단어까지만 선택 가능합니다.
최대 10 단어까지만 선택 가능합니다.
제안 방법
- , 2011). Based on these results, we investigated the effects of BALF on the normal neutrophil chemotaxis and apoptosis and the association of this effect with the cytokine and chemokine in BALF. In addition, we examined the difference between blood neutrophils and BALF neutrophils by an evaluation of the alteration of neutrophil apoptosis due to the monocyte chemoattractant protein-1 (MCP-1) named as CC chemokine ligand 2 (CCL2).
- However, the mechanism of the neutrophilic inflammation in the asthmatic airway has not been clearly elucidated yet. The main results of this study are the BALF of patients with asthma induces the normal neutrophils migration, which leads to a neutrophils recruitment at the local inflammation site such as lung tissues. The increase of MCP-1, IL-6 and IL-8 in the asthmatic BALF may be suggested as essential chemokines and cytokines in the chemotactic effect of asthmatic the BALF.
- To investigate the chemotaxis-related inflammatory factors in asthmatic BALF, both cytokines and chemokines in BALF of normal subjects and patients with asthma were analyzed using the ELISA test. As shown in Fig.
대상 데이터
- The apoptotic neutrophils were analyzed using FACSCalibur with CellQuest software (BD bioscience) and were defined as the cells that stained positive for annexin V with or without PI. Ten thousand events were collected for each experiment.
- The normal subjects had a normal lung function, no asthma history and no asthma medication was required. The patients with asthma were recruited from the Konyang University Hospital and had mild to severe disease symptoms., The symptoms were measured based on the GINA criteria (Global Initiative for Asthma) (URL: http://www.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.