Seo, Jun-Hyeok
(Top Urology Clinic)
,
Yang, Hye-Won
(Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine)
,
Joo, So-Young
(Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine)
,
Song, Su-Min
(Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine)
,
Lee, Yu-Ran
(Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine)
,
Ryu, Jae-Sook
(Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine)
,
Yoo, Eun Sang
(Department of Urology, Kyungpook National University School of Medicine)
,
Lee, Won Kee
(Center of Biostatistics, Kyungpook National University School of Medicine)
,
Kong, Hyun-Hee
(Department of Parasitology, Dong-A University College of Medicine)
,
Lee, Sang-Eun
(Division of Malaria and Parasitic Diseases, Korea National Institute of Health, Korea Centers for Diseases Control and Prevention)
,
Lee, Won-Ja
(Division of Malaria and Parasitic Diseases, Korea National Institute of Health, Korea Centers for Diseases Control and Pre)
,
Goo, Youn-Kyoung
,
Chung, Dong-Il
,
Hong, Yeonchul
Trichomonas vaginalis, a causative agent of trichomoniasis, may trigger symptomatic or asymptomatic non-gonococcal urethritis and chronic prostatitis in men. Despite the availability of highly sensitive diagnostic tests, such as nucleic acid amplification tests, including PCR, few prospective studie...
Trichomonas vaginalis, a causative agent of trichomoniasis, may trigger symptomatic or asymptomatic non-gonococcal urethritis and chronic prostatitis in men. Despite the availability of highly sensitive diagnostic tests, such as nucleic acid amplification tests, including PCR, few prospective studies present data on male T. vaginalis infection in South Korea. In the present study, the prevalence of T. vaginalis and associated clinical conditions were evaluated in 201 male patients from a primary care urology clinic in South Korea. The prevalence of T. vaginalis infection in our cohort was 4% (8/201) by PCR. T. vaginalis infection was common in men older than 40 years (median age, 52 years). Among the 8 Trichomonas-positive patients, 87.5% (7/8) had prostatic diseases, such as prostatitis and benign prostatic hyperplasia, and 25.0% (2/8) and 12.5% (1/8) were coinfected with Chlamydia trachomatis and Mycoplasma genitalium, respectively. Our results suggest that T. vaginalis infection is not rare in men attending primary care urology clinics in South Korea, especially in those older than 40 years, in whom it may explain the presence of prostatic disease. The possibility of T. vaginalis infection should be routinely considered in older male patients with prostatic diseases in South Korea.
Trichomonas vaginalis, a causative agent of trichomoniasis, may trigger symptomatic or asymptomatic non-gonococcal urethritis and chronic prostatitis in men. Despite the availability of highly sensitive diagnostic tests, such as nucleic acid amplification tests, including PCR, few prospective studies present data on male T. vaginalis infection in South Korea. In the present study, the prevalence of T. vaginalis and associated clinical conditions were evaluated in 201 male patients from a primary care urology clinic in South Korea. The prevalence of T. vaginalis infection in our cohort was 4% (8/201) by PCR. T. vaginalis infection was common in men older than 40 years (median age, 52 years). Among the 8 Trichomonas-positive patients, 87.5% (7/8) had prostatic diseases, such as prostatitis and benign prostatic hyperplasia, and 25.0% (2/8) and 12.5% (1/8) were coinfected with Chlamydia trachomatis and Mycoplasma genitalium, respectively. Our results suggest that T. vaginalis infection is not rare in men attending primary care urology clinics in South Korea, especially in those older than 40 years, in whom it may explain the presence of prostatic disease. The possibility of T. vaginalis infection should be routinely considered in older male patients with prostatic diseases in South Korea.
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대상 데이터
From May 2013 to November 2013, 201 male patients from a primary care urology clinic (Top Urology Clinic) in Daegu, South Korea, were screened for trichomoniasis by PCR and for bacterial STDs by multiplex PCR. As is required by the Declaration of Helsinki, donor confidentiality was maintained throughout, and the study was approved by the Institutional Review Board with written consent (KNUH 2013-04-051).
As is required by the Declaration of Helsinki, donor confidentiality was maintained throughout, and the study was approved by the Institutional Review Board with written consent (KNUH 2013-04-051). The bivariate analysis included 201 male patients who completed questionnaires. Demographic characteristics and urogenital symptoms of trichomoniasis were assessed by self-administered questionnaires.
이론/모형
In this study, first-voided urine (VB1) specimens, which were reported to be sufficient for the detection of T. vaginalis in men, were used in the PCR assays [16]. VB1 (30-40 ml) samples from male patients were provided in sterile 50-ml screwcap plastic tubes, immediately frozen at -20˚C, and transported on ice to a laboratory where they were stored at -70˚C.
성능/효과
As shown in Table 2, no Trichomonas-positive reaction was obtained by multiplex PCR (Table 2). In the 8 samples that were positive by PCR assay, 2 (25.0%) were positive for C. trachomatis and 1 (12.5%) was positive for M. genitalium by multiplex PCR.
920) was obtained between Trichomonas infection and older ages. The analysis of urogenital symptoms reported via self-administered questionnaires indicated that 37.5% of T. vaginalis-infected male patients had no penile discharge, odor, or lower abdominal pain, while 12.5% and 50.0% reported penile tingling and pain during urination, respectively. Among the 8 Trichomonas-positive male patients, 50.
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