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새로운 맞춤형 정밀의학과 보건의료 연구에 대한 조망

Perspective of a New Precision Medicine and Health Care Research

Abstract

The concept of precision medicine-prevention and treatment strategies that take individual variability into account-is hot issue of US in the year 2015. Precision medicine is a new concept that approach patients individually by there characteristics, such as genome, life style, environmental exposure, etc. For developing the precision medicine, National Institute of Health of US has been prepared the Precision Medicine Initiative Cohort Program, at least 1 million people cohort. The US President Obama announced the Precision Medicine Initiative on 30th January 2015. He announced that he will pioneer a new model of patient-powered research that promises to accelerate biomedical discoveries and provide clinicians with new tools, knowledge, and therapies to select which treatments will work best for which patients. Most medical treatments have been designed for the 'average patient.' As a result of this 'one-size-fits-all-approach,' treatments can be very successful for some patients but not for others. This is changing with the emergence of precision medicine, an innovative approach to disease prevention and treatment that takes into account individual differences in people's genes, environments, and lifestyles. Precision medicine gives clinicians tools to better understand the complex mechanisms underlying a patient's health, disease, or condition, and to better predict which treatments will be most effective. The healthcare researcher should prepare the new medicine era such as bio-information technology convergence, big data study.

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참고문헌 (6)

  1. US President's Council of Advisors on Science and Technology. Priorities for personalized medicine [Internet]. Washington (DC): US President's Council of Advisors on Science and Technology; 2008 [cited 2015 Dec 10]. Available from: https://www.whitehouse.gov/files/documents/ostp/PCAST/pcast_report_v2.pdf. 
  2. Personalized Medicine Coalition. Personalized medicine: the changing landscape of healthcare the changing landscape of healthcare [Internet]. Washington (DC): Personalized Medicine Coalition; 2007 [cited 2015 Dec 10]. Available from: https://www.aacc.org/-/media/files/divisions/lvd/personalized_medicine_lvd_division.pdf?la=en. 
  3. Desmond-Hellmann S, Sawyer C. National Academy of Science report. Washington (DC): National Academy of Science; 2011. 
  4. The White House Office of the Press Secretary. Fact sheet: President Obama's precision medicine initiative. Washington (DC): The White House Office of the Press Secretary; 2015. 
  5. Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med 2015;372(9):793-795. DOI: http://dx.doi.org/10.1056/NEJMp1500523.
  6. Precision Medicine Initiative (PMI) Working Group. The Precision Medicine Initiative Cohort Program: building a research foundation for 21st century medicine. Washington (DC): National Institute of Health(NIH). 

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