선택한 단어 수는 입니다.
최소 단어 이상 선택하여야 합니다.
최소 단어 이상 선택하여야 합니다.
선택한 단어 수는 30입니다.
최대 10 단어까지만 선택 가능합니다.
최대 10 단어까지만 선택 가능합니다.
제안 방법
- Finally, 73 patients were included. All data from CRP, ESR and fibrinogen test results, along with the patients ages, genders, ECOG grades and surgical operations, throughout their treatment period were collected. Then, the necessary data from the first and the last test results for the markers were collected.
- First, a cross analysis between the marker levels and the length of the treatment period divided into ≤ 20 day and ≥ 21 day groups (days refer to the length of the treatment period) was conducted without subgroups because the mean treatment period of the stage Ⅳ cancer inpatients was 21 days.
- The data for the marker levels, which were classified as decreased, increased and stable levels, were analyzed according to the length of the treatment period. First, a oneway analysis of the correlations between the CRP, ESR, and fibrinogen levels of the 73 patients and the length of the treatment period was conducted. Second, a one-way analysis of the correlations between the marker levels and the length of the treatment period was conducted for both male and female subgroups.
- All data were collected after de-identification of the patient by using a unique review number. Information on the variations in the patients CRP, ESR, and fibrinogen levels was analyzed in separate groups according to the treatment period, past surgery, and gender. The clinical characteristics of all 73 patients are described in Tables 1, 2, 3.
- Second, a cross analysis between the marker levels and the length of the treatment period divided into ≤ 20 day and ≥ 21 day groups was conducted for both the male and the female subgroups.
- First, a oneway analysis of the correlations between the CRP, ESR, and fibrinogen levels of the 73 patients and the length of the treatment period was conducted. Second, a one-way analysis of the correlations between the marker levels and the length of the treatment period was conducted for both male and female subgroups. All one-way analyses were conducted by using the Kruskal-Wallis test.
- The data for the marker levels, which were classified as decreased, increased and stable levels, were analyzed according to the length of the treatment period. First, a oneway analysis of the correlations between the CRP, ESR, and fibrinogen levels of the 73 patients and the length of the treatment period was conducted.
- Third, a cross analysis between the marker levels and the length of the treatment period divided into ≤ 20 day and ≥ 21 day groups was conducted for both the surgery and the non-surgery subgroups.
- Thus, a need exists to conduct additional studies that separate patients into a few groups by the degree of the advanced or the metastatic state of the cancer. Third, this study did not analyze each primary site of cancer because of the small population sizes when the patients were separated according to the primary site of the cancer. Therefore, additional studies with large population sizes are needed.
- However, the above studies have mainly analyzed the levels of fibrinogen or NK cells without assessing the CRP or the ESR levels. Thus, we decided to carry out this study of the correlation between the treatment period of wheel balanced cancer therapy (WBCT), which is a cancer care program of the East West Cancer Center (EWCC) and the CRP, ESR and fibrinogen levels associated with tumor progression, metastasis, and survival rates.
- We analyzed the variations in the marker levels according to gender separately in the ≥ 21 day and the ≤ 20 day groups by using Fisher's exact test and the likelihood ratio test.
- We analyzed the variations in the marker levels separately for the surgery and the no-surgery subgroups in the ≥ 21 day and the ≤ 20 day groups by using Fisher's exact test and the likelihood ratio test, and the results were classified as decreased, increased, stable or unknown.
- We divided the patients according to the treatment period into the ≥ 21 day group and ≤ 20 day group and analyzed the variations of the markers by using Fisher's exact test and the likelihood ratio test.
대상 데이터
- Data were from a single site and were collected under a protocol approved by the Daejeon University Institutional Review Boards (IRB, IRB approval number: 14-09). StageⅣcancer patients hospitalized at the EWCC for Korean medicine therapy alone from February 1, 2008, to November 30, 2013, were included in this study. Patients who had undergone chemotherapy or radiotherapy during the treatment period were excluded as were patients whose laboratory follow-up tests did not include at least two data points for at least one marker (CRP, ESR, or fibrinogen), patients whose Eastern Cooperative Oncology Group (ECOG) grade was 3 or more, and patients with an unknown ECOG grade (Fig.
데이터처리
- Third, a cross analysis between the marker levels and the length of the treatment period divided into ≤ 20 day and ≥ 21 day groups was conducted for both the surgery and the non-surgery subgroups. Additionally, a cross analysis of the correlation between the marker levels and surgery was conducted. All cross analyses were conducted by using Fisher's exact test and the likelihood ratio test.
- Second, a one-way analysis of the correlations between the marker levels and the length of the treatment period was conducted for both male and female subgroups. All one-way analyses were conducted by using the Kruskal-Wallis test.
- In the case of the CRP and the ESR, the study populations were large enough for the tests, but they also did not meet the normality assumption required by the Shapiro-Wilk test. Thus, variations in the CRP and the ESR levels were analyzed by using the Kruskal-Wallis test.
이론/모형
- All cross analyses were conducted by using Fisher's exact test and the likelihood ratio test.
- Because all three markers did not meet the normality assumption required by the Shapiro-Wilk test, the nonparametric Kruskal-Wallis test was used for the one-way analyses. For cross analyses of these markers, Fisher's exact test and the likelihood ratio test were used together.
- Differences among the treatment period lengths for decreased, increased, stable, and unknown marker levels were analyzed by using the Kruskal-Wallis test and showed statistical significance. The levels of the CRP and the ESR, but not those of fibrinogen showed a statistically significant correlation with the treatment period.
- For cross analyses of these markers, Fisher's exact test and the likelihood ratio test were used together.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.