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NTIS 바로가기한국임상약학회지 = Korean journal of clinical pharmacy, v.25 no.3, 2015년, pp.200 - 208
정은주 (경성대학교 약학대학) , 이채원 (경성대학교 약학대학) , 백인환 (경성대학교 약학대학)
Objective: Patients with acute coronary syndrome (ACS) are typically managed with dual antiplatelet therapy of acetylsalicylic acid (aspirin) and
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핵심어 | 질문 | 논문에서 추출한 답변 |
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급성관상동맥증후군이란? | 급성관상동맥증후군(acute coronary syndrome; ACS) 이란, 관상동맥의 혈관 내에 급성으로 크고 작은 혈전이 생겨 이로 인해 순간적인 혈관폐쇄 또는 혈전에서 분비되는 여러 혈관 수축성 물질들이 혈관을 더 심하게 수축시켜 심한 관상동맥폐쇄로 인하여 심장으로의 혈류공급이 부족해져서 생기는 질환이다.1) 심혈관질환은 전 세계적으로 사망원인 1위의 질환이며, 여러 심혈관질환 중에서도 특히나 급성관상동맥증후군은 심혈관질환의 주요 위험요인이다. | |
급성관상동맥증후군의 치료는 어떤 것들이 있는가? | 급성관상동맥증후군의 치료는 크게 4가지로 나뉜다. 허혈증상과 심근손상을 줄이고 예방하기 위한 항허혈 치료, 병태생리에 가장 중요하게 작용하는 항혈전 치료, 환자의 위험도에 따라 관동맥 협착이나 폐색을 해결하기 위한 혈관 재관류요법, 그리고 심혈관계 발작을 줄이기 위한 위험인자 조절과 약물치료가 있다.8) 이 중에서 급성관상동맥증후군의 표준약물치료는 항혈전 치료에 속하는 항혈소판 약물요법이다. | |
급성관상동맥증후군은 어떻게 나뉘어 지는가? | 2) 다시 말해, 급성관상동맥증후군은 심근의 혈액공급 저하에 기인하는 모든 급성 증상, 즉 급성심근허혈(myocardial ischemia)에 기인한 모든 임상증세를 아우르는 광범위한 용어이다.3) 이러한 급성관상동맥증후군은 불안정형 협심증(unstable angina, UA) 과 급성심근경색증으로 나뉠 수 있으며, 급성심근경색증은 다시 ST분절 상승 심근경색증(ST-elevation myocardial infarction, STEMI)과 ST분절 비상승 심근경색증(Non-ST-elevation myocardial infarction, NSTEMI) 로 나뉘어 진다(Fig. 1). |
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