[논문]Fabrication and Characterization of Hydroxyapatite/Mullite and Tricalcium Phosphate/Al2O3 Composites Containing 30 wt% of Bioactive Components

Ha, Jung-Soo

doi:10.4191/kcers.2015.52.5.374

[국내논문] Fabrication and Characterization of Hydroxyapatite/Mullite and Tricalcium Phosphate/Al2O3 Composites Containing 30 wt% of Bioactive Components 원문보기

한국세라믹학회지 = Journal of the Korean Ceramic Society, v.52 no.5, 2015년, pp.374 - 379

Ha, Jung-Soo (School of Materials Science and Engineering, Andong National University)

Abstract ▼ AI-Helper

Mullite-matrix and $Al_2O_3$-matrix composites were fabricated with 30 wt% hydroxyapatite (HA) and tricalcium phosphate (TCP), respectively, as additives to give bioactivity. A diphasic gel process was employed to lower the densification temperature of the mullite matrix to $1320^{\circ}C$. A polymer complexation process was used to synthesize a TCP powder that was fully densified at $1250^{\circ}C$, for application to the matrix. For the HA/mullite composite, HA decomposed during sintering by reactions with the matrix components of $Al_2O_3$ and $SiO_2$, resulting in a mixture of $Al_2O_3$, TCP, and other minor phases with a low densification of less than 88% of the theoretical density (TD). In contrast, the TCP/$Al_2O_3$ composite was highly densified by sintering at $1350^{\circ}C$ to 96%TD with no reaction between the components. Different from the TCP monolith, the TCP/$Al_2O_3$ composite also showed a fine microstructure and intergranular fracture, both of which characteristics are advantageous for strength and fracture toughness.

Keyword

AI 본문요약
AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

제안 방법

The objective of the present study is to fabricate 30 wt% HA/mullite and 30 wt% TCP/Al₂O₃ composites, following the latter approach using HA and TCP as bioactive additives. The reason for choosing the figure of 30 wt% is that this amount was found through cell proliferation rate measurements to be enough to impart bioactivity in the HA/ZA composites.
First, experiments to determine the sintering conditions were performed on the HA and SGM powders. The optimum conditions were found to be 1200℃/1h for HA and 1320℃/1h for SGM, which had sintered densities of 99% and 95%TDs, respectively.
Fabrication of mullite and Al₂O₃ composites containing 30 wt% HA and TCP, respectively, as additives to impart bioactivity was attempted. To achieve this goal, the densification temperature of the mullite matrix was lowered to 1320℃ and a TCP powder that was fully densified at 1250℃ was synthesized and applied.

대상 데이터

HA powder (3 μm; HA-10, Sunkoo, South Korea) was used as the bioactive additive for the composite.
In order to prepare the mullite matrix powder via the diphasic gel process¹⁷⁾ (hereafter named SGM), a boehmite powder (AlOOH; 80 wt% Al₂O₃, 30 nm; Dispal 11N7-80, Sasol, Germany) and a SiO₂ sol (30 wt% SiO₂, 10 - 20 nm; Silifog 45AK, Ace Nanochem, South Korea) were used as starting materials for Al₂O₃ and SiO₂. First, the boehmite powder was weighed to make 6 wt% solid content and added to distilled water with stirring to prepare a boehmite sol.

이론/모형

The densities of the sintered samples were measured by the Archimedes method. Phases and microstructures of the powder and sintered samples were determined by X-ray diffraction (XRD) and scanning electron microscopy (SEM).

참고문헌 (20)

W. Suchanek and M. Yoshimura, "Processing and Properties of Hydroxyapatite-based Biomaterials for Use as a Hard Tissue Replacement Implants," J. Mater. Res., 13 [1] 94-117 (1998).

상세보기
H. Y. Juang and M. H. Hon, "Fabrication and Mechanical Properties of Hydroxyapatite-alumina Composites," Mater. Sci. Eng. C, 2 77-81 (1994).

상세보기
J. Li, B. B. Fartash, and L. Hermansson, "Hydroxyapatitealumina Composites and Bone-bonding," Biomaterials, 16 417-22 (1995).

상세보기
S. Gautier, E. Champion, and D. B. Assollant, "Processing, Microstructure and Toughness of Al2O3 Platelet-reinforced Hydroxyapatite," J. Eur. Ceram. Soc., 17 1361-69 (1997).

상세보기
B. Viswanath and N. Ravishankar, "Interfacial Reactions in Hydroxyapatite/Alumina Nanocomposites," Scripta Mater., 55 863-66 (2006).

상세보기
Y. X. Pang, X. Bao, and L. Weng, "Preparation of Tricalcium Phosphate/Alumina Composite Nanoparticles and Self-reinforcing Composites by Simultaneous Precipitation," J. Mater. Sci., 39 6311-23 (2004).

상세보기
E. Adolfsson, P. Alberius-Henning, and L. Hermansson, "Phase Analysis and Thermal Stability of Hot Isostatically Pressed Zirconia-hydroxyapatite Composites," J. Am. Ceram. Soc., 83 2798-802 (2000).

상세보기
R. R. Rao and T. S. Kannan, "Synthesis and Sintering of Hydroxyapatite-zirconia Composites," Mater. Sci. Eng. C, 20 187-93 (2002).

상세보기
V. V. Silva, F. S. Lamerias, and R. Z. Dominguez, "Microstructural and Mechanical Study of Zirconia-hydroxyapatite (ZH) Composite Ceramics for Biomedical Applications," Comps. Sci. Technol., 61 301-10 (2001).

상세보기
S. Nath, K. Biswas, K. Wang, R. K. Bordia, and B. Basu, "Sintering, Phase Stability, and Properties of Calcium Phosphate-mullite Composites," J. Am. Ceram. Soc., 93 [6] 1639-49 (2010).

상세보기
I. Manjubala and M. Sivakumar, "In-situ Synthesis of Biphasic Calcium Phosphate Ceramics Using Microwave Irradiation," Mater. Chem. Phys., 71 272-78 (2001).

상세보기
Z. Shen, E. Adolfsson, M. Nygren, L. Gao, H. Kawaoka, and K. Niihara, "Dense Hydroxyapatite Composites with High Strength for Biological Applications," Adv. Mater., 13 [3] 214-16 (2001).
Y. -M. Kong, C. -J. Bae, S. -H. Lee, H. -W. Kim, and H. -E. Kim, "Improvement in Biocompatibility of $ZrO_2-Al_2O_3$ Nano-composite by Addition of HA," Biomaterials, 26 509-17 (2005).

상세보기
S. Sakka, F. B. Ayed, and J. Bouaziz, "Mechanical Properties of Tricalcium Phosphate-alumina Composites," IOP Conference Series: Mater. Sci. Eng., 28 [1] 012028 (2012).

상세보기
S. Sakka, J. Bouaziz, and F. B. Ayed, "Mechanical Properties of Biomaterials Based on Calcium Phosphates and Bioinert Oxides for Applications in Biomedicine," pp. 23-50 in Advances in Biomaterials Science and Biomedical Applications. Ed. by R. Pignatello, INTECH, 2013.
A. Priya, S. Nath, K. Biswas, and B. Basu, "In Vitro Dissolution of Calcium Phosphate-mullite Composite in Simulated Body Fluid," J. Mater. Sci.: Mater. Med., 21 1817-28 (2010).

상세보기
J. -S. Ha and K. K. Chawla, "The Effect of Precursor Characteristics on the Crystallization and Densification of Diphasic Mullite Gels," Ceram. Int., 19 299-305 (1993).

상세보기
S. -J. Lee, S. -I. Ko, M. -H. Lee, and N. -S. Oh, "Fabrication of Nano-sized β-TCP Powder by an Organic-inorganic Solution Route," J. Ceram. Proc. Res., 8 [4] 281-84 (2007).
H. -J. Kleebe, G. Pezzotti, and G. Ziegler, "Microstructure and Fracture Toughness of $Si_3N_4$ Ceramics: Combined Roles of Grain Morphology and Secondary Phase Chemistry," J. Am. Ceram. Soc., 82 [7] 1857-67 (1999).

상세보기
J. H. She and K. Ueno, "Effect of Additive Content on Liquid- phase Sintering on Silicon Carbide Ceramics," Mater. Res. Bull., 34 [10/11] 1629-36 (1999).

상세보기

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증