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Biomolecules & therapeutics, v.24 no.1, 2016년, pp.1 - 8
Wu, Nan (Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University) , Yang, Mingyao (Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University) , Gaur, Uma (Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University) , Xu, Huailiang (Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University) , Yao, Yongfang (Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University) , Li, Diyan (Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University)
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Alpha-ketoglutarate (AKG) is a key molecule in the Krebs cycle determining the overall rate of the citric acid cycle of the organism. It is a nitrogen scavenger and a source of glutamate and glutamine that stimulates protein synthesis and inhibits protein degradation in muscles. AKG as a precursor o...
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Abcouwer SF 2000 Effects of glutamine on immune cells Nutrition 16 67 69 10.1016/S0899-9007(99)00237-3 10674240
Abrahams JP Leslie AG Lutter R Walker JE 1994 Structure at 2.8 A resolution of F1-ATPase from bovine heart mitochondria Nature 370 621 628 10.1038/370621a0 8065448
Alpers DH 2006 Glutamine: do the data support the cause for glutamine supplementation in humans? Gastroenterology 130 S106 S116 10.1053/j.gastro.2005.11.049 16473057
Andersen NK Tatara MR Krupski W Majcher P Harrison AP 2008 The long-term effect of alpha-ketoglutarate, given early in postnatal life, on both growth and various bone parameters in pigs J Anim Physiol Anim Nutr 92 519 528 10.1111/j.1439-0396.2007.00742.x
Ashkanazi J Carpertier Y Michelsen C 1980 Muscle and plasma amino acids following injury Ann Surg 192 78 85 10.1097/00000658-198007000-00014 7406567
Barthel A Schmoll D Unterman TG 2005 FoxO proteins in insulin action and metabolism Trends Endocrinol Metab 16 183 189 10.1016/j.tem.2005.03.010 15860415
Bellon G Chaqour B Wegrowski Y Monboisse JC Borel JP 1995 Glutamine increases collagen gene transcription in cultured human fibroblasts Biochim. Biophys. Acta 1268 311 323 10.1016/0167-4889(95)00093-8 7548230
Bieńko M Radzki R Puzio I Filip R Pierzynowski S Studziński T 2002 The influence of alpha-ketoglutarate (AKG) on mineralization of femur in rats with established osteopenia Acta Orthop Scand 73 52
Bissonnette R Friedmann D Giroux JM Dolenga M Hechtman P Der Kaloustian VM Dubuc R 1993 Prolidase deficiency: a multisystemic hereditary disorder J Am Acad Dermatol 29 818 821 10.1016/0190-9622(93)70245-O 8408817
Blagosklonny MV 2006 Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition Cell Cycle 5 2087 2102 10.4161/cc.5.18.3288 17012837
Boyer PD 1997 The ATP synthase-a splendid molecular machine Annu Rev Biochem 66 717 749 10.1146/annurev.biochem.66.1.717 9242922
Brauer MJ Yuan J Bennett BD Lu W Kimball E Botstein D Rabinowitz JD 2006 Conservation of the metabolomic response to starvation across two divergent microbes Proc Natl Acad Sci USA 103 19302 19307 10.1073/pnas.0609508103 1697828 --> 17159141
Brugnara L Vinaixa M Murillo S Samino S Rodriguez MA Beltran A Lerin C Davison G Correig X Novials A 2012 Metabolomics approach for analyzing the effects of exercise in subjects with type 1 diabetes mellitus PloS one 7 e40600 10.1371/journal.pone.0040600 3394718 --> 22792382
Brunet A 2004 [The multiple roles of FOXO transcription factors] Med Sci 20 856 859
Chenu C 2002a Glutamatergic innervation in bone Microsc Res Tech 58 70 76 10.1002/jemt.10120 12203705
Chenu C 2002b Glutamatergic regulation of bone remodeling J Musculoskelet Neuronal Interact 2 282 284 15758455
Chin RM Fu X Pai MY Vergnes L Hwang H Deng G Diep S Lomenick B Meli VS Monsalve GC 2014 The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR Nature 510 397 401 4263271 --> 24828042
Colomb V Dabbas M Goulet O Talbotec C Corriol O Ricour C 2004 Prepubertal growth in children with long-term parenteral nutrition Horm Res Paediatr 58 2 6 10.1159/000064760
Curran SP Ruvkun G 2007 Lifespan regulation by evolutionarily conserved genes essential for viability PLoS Genet 3 e56 10.1371/journal.pgen.0030056 1847696 --> 17411345
Cynober L 2004 Ornithine α-ketoglutarate as a potent precursor of arginine and nitric oxide: a new job for an old friend J Nutr 134 2858S 2862S 15465801
Dąbek M Kruszewska D Filip R Hotowy A Pierzynowski Ł Wojtasz-Pająk A Szymanczyk S Valverde Piedra J Werpachowska E Pierzynowski S 2005 α-Ketoglutarate (AKG) absorption from pig intestine and plasma pharmacokinetics J Anim Physiol Anim Nutr 89 419 426 10.1111/j.1439-0396.2005.00566.x
Dakshayani K Subramanian P 2006 α-ketoglutarate modulates the circadian patterns of lipid peroxidation and antioxidant status during N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. J. Med. Food 9 90 97 10.1089/jmf.2006.9.90 16579734
Danbolt NC 2001 Glutamate uptake Prog Neurobiol 65 1 105 10.1016/S0301-0082(00)00067-8 11369436
Dillin A Hsu AL Arantes-Oliveira N Lehrer-Graiwer J Hsin H Fraser AG Kamath RS Ahringer J Kenyon C 2002 Rates of behavior and aging specified by mitochondrial function during development Science 298 2398 2401 10.1126/science.1077780 12471266
Dobrowolski PJ Piersiak T Surve VV Kruszewska D Gawron A Pacuska P Håkanson R Pierzynowski SG 2008 Dietary α-ketoglutarate reduces gastrectomy-evoked loss of calvaria and trabecular bone in female rats Scand J Gastroenterol 43 551 558 10.1080/00365520701824951 18415747
Espat NJ Watkins KT Lind DS Weis JK Copeland EM Souba WW 1996 Dietary modulation of amino acid transport in rat and human liver J Surg Res 63 263 268 10.1006/jsre.1996.0258 8661208
Fayh AP Friedman R Sapata KB Oliveira AR 2007 [Effect of L-arginine supplementation on secretion of human growth hormone and insulin-like growth factor in adults] Arq Bras Endocrinol Metabol 51 587 592 10.1590/S0004-27302007000400013 17684620
Furukawa S Saito H Inoue T Matsuda T Fukatsu K Han I Ikeda S Hidemura A 2000 Supplemental glutamine augments phagocytosis and reactive oxygen intermediate production by neutrophils and monocytes from postoperative patients in vitro Nutrition 16 323 329 10.1016/S0899-9007(00)00228-8 10793298
Gianotti L Alexander JW Gennari R Pyles T Babcock GF 1995 Oral glutamine decreases bacterial translocation and improves survival in experimental gut-origin sepsis J Parenter Enteral Nutr 19 69 74 10.1177/014860719501900169
Giustina A Mazziotti G Canalis E 2008 Growth hormone, insulin-like growth factors, and the skeleton Endocr Rev 29 535 559 10.1210/er.2007-0036 2726838 --> 18436706
Gross DN van den Heuvel AP Birnbaum MJ 2008 The role of FoxO in the regulation of metabolism Oncogene 27 2320 2336 10.1038/onc.2008.25 18391974
Gu Y Genever P Skerry T Publicover S 2002 The NMDA type glutamate receptors expressed by primary rat osteoblasts have the same electrophysiological characteristics as neuronal receptors Calcif Tissue Int 70 194 203 10.1007/s00223-001-2004-z 11907717
Hammarqvist F Wernerman J Ali R von der Decken A Vinnars E 1989 Addition of glutamine to total parenteral nutrition after elective abdominal surgery spares free glutamine in muscle, counteracts the fall in muscle protein synthesis, and improves nitrogen balance Ann Surg 209 455 461 10.1097/00000658-198904000-00011 1493967 --> 2494960
Hansen M Taubert S Crawford D Libina N Lee SJ Kenyon C 2007 Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans Aging Cell 6 95 110 10.1111/j.1474-9726.2006.00267.x 17266679
Hardie DG Ross FA Hawley SA 2012 AMPK: a nutrient and energy sensor that maintains energy homeostasis Nat Rev Mol Cell Biol 13 251 262 10.1038/nrm3311 22436748
Harrison AP Pierzynowski S 2008 Biological effects of 2-oxoglutarate with particular emphasis on the regulation of protein, mineral and lipid absorption/metabolism, muscle performance, kidney function, bone formation and cancerogenesis, all viewed from a healthy ageing perspective state of the art-review article J Physiol Pharmacol 59 91 106 18802218
Harrison AP Tygesen MP Sawa-Wojtanowicz B Husted S Tatara M 2004 α-Ketoglutarate treatment early in postnatal life improves bone density in lambs at slaughter Bone 35 204 209 10.1016/j.bone.2004.03.016 15207758
Hixt U Müller H 1996 L-alanyl-glutamine-a glutamine dipeptide for paraenteral nutrition Environ Health Perspect 2 72 76
Huang X Liu J Withers BR Samide AJ Leggas M Dickson RC 2013 Reducing signs of aging and increasing lifespan by drug synergy Aging Cell 12 652 660 10.1111/acel.12090 3714353 --> 23601176
Inoki K Guan K-L 2006 Complexity of the TOR signaling network Trends Cell Biol 16 206 212 10.1016/j.tcb.2006.02.002 16516475
Isemura M Hanyu T Gejyo F Nakazawa R Igarashi R Matsuo S Ikeda K Sato Y 1979 Prolidase deficiency with imidodipeptiduria. A familial case with and without clinical symptoms Clin. Chim. Acta 93 401 407 10.1016/0009-8981(79)90291-2 445856
Jones C Allan Palmer T Griffiths R 1999 Randomized clinical outcome study of critically ill patients given glutamine-supplemented enteral nutrition Nutrition 15 108 115 10.1016/S0899-9007(98)00172-5 9990574
Junghans P Derno M Pierzynowski S Hennig U Eberhard Rudolph P Souffrant WB 2006 Intraduodenal infusion of α-ketoglutarate decreases whole body energy expenditure in growing pigs Clin Nutr 25 489 496 10.1016/j.clnu.2005.11.003 16376464
Kaeberlein M Burtner CR Kennedy BK 2007 Recent developments in yeast aging PLoS Genet 3 e84 10.1371/journal.pgen.0030084 1877880 --> 17530929
Kaminsky YG Kosenko EA Kondrashova MN 1982 Metabolites of citric acid cycle, carbohydrate and phosphorus metabolism, and related reactions, redox and phosphorylating states of hepatic tissue, liver mitochondria and cytosol of the pigeon, under normal feeding and natural nocturnal fasting conditions Comp Biochem Physiol B 73 957 963 7151427
Kapahi P Zid B 2004 TOR pathway: linking nutrient sensing to life span Sci Aging Knowledge Environ 2004 pe34 10.1126/sageke.2004.36.pe34 2754831 --> 15356349
Kapahi P Zid BM Harper T Koslover D Sapin V Benzer S 2004 Regulation of lifespan in drosophila by modulation of genes in the TOR signaling pathway Curr Biol 14 885 890 10.1016/j.cub.2004.03.059 2754830 --> 15186745
Karna E Szoka L Palka JA 2013 The mechanism of hydralazine-induced collagen biosynthesis in cultured fibroblasts Naunyn Schmiedebergs ArchPharmacol 386 303 309 10.1007/s00210-013-0836-5
Katewa SD Kapahi P 2011 Role of TOR signaling in aging and related biological processes in Drosophila melanogaster Exp Gerontol 46 382 390 10.1016/j.exger.2010.11.036 3058120 --> 21130151
Korkmaz A Yurdakok M Yigit S Tekinalp G 2007 Long-term enteral glutamine supplementation in very low birth weight infants: effects on growth parameters Turk J Pediatr 49 37 44 17479642
Kowalik S Śliwa E Tatara MR Krupski W Majcher P Studziński T 2005 Influence of alpha-ketoglutarate on mineral density and geometrical and mechanical parameters of femora during postnatal life in piglets Bull. Vet. Inst. Pulawy 49 107 111
Kristensen NB Jungvid H Fernández JA Pierzynowski S 2002 Absorption and metabolism of α-ketoglutarate in growing pigs J Anim Physiol Anim Nutr 86 239 245 10.1046/j.1439-0396.2002.00380.x
Lamande SR Bateman JF 1999 Procollagen folding and assembly: the role of endoplasmic reticulum enzymes and molecular chaperones Semin Cell Dev Biol 10 455 464 10.1006/scdb.1999.0317 10597628
Lambert BD Filip R Stoll B Junghans P Derno M Hennig U Souffrant WB Pierzynowski S Burrin DG 2006 First-pass metabolism limits the intestinal absorption of enteral α-ketoglutarate in young pigs J Nutr 136 2779 2784 17056800
Le Boucher J Coudray-Lucas C Lasnier E Jardel A Ekindjian OG Cynober LA 1997 Enteral administration of ornithine alpha-ketoglutarate or arginine alpha-ketoglutarate: a comparative study of their effects on glutamine pools in burn-injured rats Crit Care Med 25 293 298 10.1097/00003246-199702000-00017 9034267
Le Boucher J Cynober LA 1997 Ornithine alpha-ketoglutarate: the puzzle Nutrition 14 870 873 9834933
Lee SS Lee RY Fraser AG Kamath RS Ahringer J Ruvkun G 2003 A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat Genet 33 40 48 10.1038/ng1056 12447374
Lomenick B Hao R Jonai N Chin RM Aghajan M Warburton S Wang J Wu RP Gomez F Loo JA 2009 Target identification using drug affinity responsive target stability (DARTS) Proc Natl Acad Sci USA 106 21984 21989 10.1073/pnas.0910040106 2789755 --> 19995983
Luong N Davies CR Wessells RJ Graham SM King MT Veech R Bodmer R Oldham SM 2006 Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity Cell Metab 4 133 142 10.1016/j.cmet.2006.05.013 16890541
MacFie J McNaught C 2002 Glutamine and gut barrier function Nutrition 18 433 434 10.1016/S0899-9007(02)00766-9 11985953
Meléndez A Tallóczy Z Seaman M Eskelinen EL Hall DH Levine B 2003 Autophagy genes are essential for dauer development and life-span extension in C. elegans Science 301 1387 1391 10.1126/science.1087782 12958363
Mentaverri R Kamel S Wattel A Prouillet C Sevenet N Petit J Tordjmann T Brazier M 2003 Regulation of bone resorption and osteoclast survival by nitric oxide: Possible involvement of NMDA-receptor J Cell Biochem 88 1145 1156 10.1002/jcb.10463 12647297
Myara I Charpentier C Lemonnier A 1984 Prolidase and prolidase deficiency Life Sci 34 1985 1998 10.1016/0024-3205(84)90363-1 6727550
Myllyharju J 2003 Prolyl 4-hydroxylases, the key enzymes of collagen biosynthesis Matrix Biol 22 15 24 10.1016/S0945-053X(03)00006-4 12714038
Neu J Shenoy V Chakrabarti R 1996 Glutamine nutrition and metabolism: where do we go from here? FASEB J 10 829 837 8666159
Ogle CK Ogle JD Mao JX Simon J Noel JG Li B-G Alexander JW 1994 Effect of glutamine on phagocytosis and bacterial killing by normal and pediatric burn patient neutrophils J Parenter Enteral Nutr 18 128 133 10.1177/0148607194018002128
Palka JA Phang JM 1997 Prolidase activity in fibroblasts is regulated by interaction of extracellular matrix with cell surface integrin receptors J Cell Biochem 67 166 175 10.1002/(SICI)1097-4644(19971101)67:2 3.0.CO;2-V 9328822
Panosyan EH Grigoryan RS Avramis IA Seibel NL Gaynon PS Siegel SE Fingert HJ AVRAMIS VI 2004 Deamination of glutamine is a prerequisite for optimal asparagine deamination by asparaginases in vivo (CCG-1961) Anticancer Res 24 1121 1126 15154634
Parry-Billings M Calder P Newsholme E Evans J 1990 Does glutamine contribute to immunosuppression after major burns? Lancet 336 523 525 10.1016/0140-6736(90)92083-T 1975037
Pesty FH Sultan F Braun B 1997 Glutamine homologues and derivatives: A limiting factor in current artificial nutrition? Nutrition 13 575 577 10.1016/S0899-9007(97)00025-7 9263243
Pierzynowski S Sjodin A 1998 Perspectives of glutamine and its derivatives as feed additives for farm animals J Anim Feed Sci 7 79 91
Pierzynowski SG Filip R Harrison A 2007 Effect of feed supplementation with alpha-ketoglutarate, combined with vitamin B∼ 6 or C, on the performance and haemoglobin and amino acid levels in growing rats Bull. Vet. Inst. Pulawy 51 289 296
Radzki R Bienko M Puzio I Filip R Pierzynowski S Studzinski T 2002 The effect of alpha-ketoglutarate (AKG) on mineralization of femur in ovariectomized rats Acta Orthop Scand 73 52
Rani RS Leela AC Rao GN 2012 Effect of dielectric constant on protonation equilibria of l-aspartic acid and ethylenediamine in 1, 2-propanediol-water mixtures P Natl A Sci India A 82 313 316 10.1007/s40010-012-0047-3
Riedel E Nundel M Hampl H 1996 alpha-Ketoglutarate application in hemodialysis patients improves amino acid metabolism Nephron 74 261 265 10.1159/000189319 8893139
Roth E Funovics J Mühlbacher F Schemper M Mauritz W Sporn P Fritsch A 1982 Metabolic disorders in severe abdominal sepsis: glutamine deficiency in skeletal muscle Clin Nutr 1 25 41 10.1016/0261-5614(82)90004-8 16829366
Salvalaggio PR Campos AC 2002 Bacterial translocation and glutamine Nutrition 18 435 437 10.1016/S0899-9007(02)00770-0 11985955
Sawyer DW Donowitz GR Mandell GL 1989 Polymorphonuclear neutrophils: an effective antimicrobial force 11 S1532 S1544 2557663
Schlegel L Coudray-Lucas C Barbut F Le Boucher J Jardel A Zarrabian S Cynober L 2000 Bacterial dissemination and metabolic changes in rats induced by endotoxemia following intestinal E. coli overgrowth are reduced by ornithine α-ketoglutarate administration J Nutr 130 2897 2902 11110843
Selman C Tullet JM Wieser D Irvine E Lingard SJ Choudhury AI Claret M Al-Qassab H Carmignac D Ramadani F 2009 Ribosomal protein S6 kinase 1 signaling regulates mammalian life span Science 326 140 144 10.1126/science.1177221 19797661
Sheaffer KL Updike DL Mango SE 2008 The target of rapamycin pathway antagonizes pha-4/FoxA to control development and aging Curr Biol 18 1355 1364 10.1016/j.cub.2008.07.097 2615410 --> 18804378
Śliwa E 2010 2-Oxoglutaric acid administration diminishes fundectomy-induced osteopenia in pigs J Anim Physiol Anim Nutr 94 e86 e95 10.1111/j.1439-0396.2009.00985.x
Śliwa E Dobrowolski P Tatara M Piersiak T Siwicki A Rokita E Pierzynowski S 2009 Alpha-ketoglutarate protects the liver of piglets exposed during prenatal life to chronic excess of dexamethasone from metabolic and structural changes J Anim Physiol Anim Nutr 93 192 202 10.1111/j.1439-0396.2007.00805.x
Son ED Choi GH Kim H Lee B Chang IS Hwang JS 2007 Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice Biol Pharm Bull 30 1395 1399 10.1248/bpb.30.1395 17666792
Spencer GJ McGrath CJ Genever PG 2007 Current perspectives on NMDA-type glutamate signalling in bone Int J Biochem Cell Biol 39 1089 1104 10.1016/j.biocel.2006.11.002 17188550
Stanfel MN Shamieh LS Kaeberlein M Kennedy BK 2009 The TOR pathway comes of age Biochim. Biophys. Acta 1790 1067 1074 10.1016/j.bbagen.2009.06.007 3981532 --> 19539012
Stoll B McNelly S Buscher HP Häussinger D 1991 Functional hepatocyte heterogeneity in glutamate, aspartate and α-ketoglutarate uptake: A histoautoradiographical study Hepatology 13 247 253 10.1002/hep.1840130208 1671664
Tapiero H Mathe G Couvreur P Tew K 2002 II. Glutamine and glutamate Biomed Pharmacother 56 446 457 10.1016/S0753-3322(02)00285-8 12481981
Tatara M Brodzki A Krupski W Silmanowicz P Majcher P Pierzynowski S Studziński T 2005a Effects of alpha-ketoglutarate on bone homeostasis and plasma amino acids in turkeys Poult Sci 84 1604 1609 10.1093/ps/84.10.1604 16335130
Tatara M Tygesen MP Sawa-Wojtanowicz B Krupski W Majcher P Harrison AP 2007 Bone development: The effect of short-term alpha-ketoglutarate administration on long-term mechanical properties of ribs in ram lambs Small Ruminant Res 67 179 183 10.1016/j.smallrumres.2005.09.031
Tatara MR Silmanowicz P Majcher P Krupski W Studziński T 2005b Influence of alpha-ketoglutarate on cortical bone atrophy after denervation of the humerus in turkey. Bull. Vet. Inst. Pulawy 49 113 116
Taylor A 2002 Osteoblastic glutamate receptor function regulates bone formation and resorption J Musculoskelet Neuronal Interact 2 285 290 15758456
Tocaj A Filip R Lindergard B Wernerman J Studzinski T Ohman K Pierzynowski S 2003 Alpha-ketoglutarate (AKG) inhibit osteoporosis development in postmenopausal women Journal of Bone and Mineral Research 18 S267 S267 Amer Soc Bone & Mineral Res 2025 M St, Nw, Ste 800, Washington Dc 20036-3309 USA.
Toivonen JM Walker GA Martinez-Diaz P Bjedov I Driege Y Jacobs HT Gems D Partridge L 2007 No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects PLoS Genet 3 e95 10.1371/journal.pgen.0030095 1892600 --> 17571923
Tritos NA Biller BM 2009 Growth hormone and bone Curr Opin Endocrinol Diabetes Obes 16 415 422 10.1097/MED.0b013e3283319e6d 19770650
Tsang WY Sayles LC Grad LI Pilgrim DB Lemire BD 2001 Mitochondrial respiratory chain deficiency in Caenorhabditis elegans results in developmental arrest and increased life span. J Biol Chem 276 32240 32246 10.1074/jbc.M103999200 11410594
Urban J Soulard A Huber A Lippman S Mukhopadhyay D Deloche O Wanke V Anrather D Ammerer G Riezman H 2007 Sch9 Is a Major Target of TORC1 in Saccharomyces cerevisiae Mol. Cell 26 663 674 10.1016/j.molcel.2007.04.020 17560372
Vellai T Takacs-Vellai K Zhang Y Kovacs AL Orosz L Müller F 2003 Influence of TOR kinase on lifespan in C. elegans Nature 426 620 10.1038/426620a 14668850
Velvizhi S Dakshayani KB Subramanian P 2002 Effects of α-ketoglutarate on antioxidants and lipid peroxidation products in rats treated with ammonium acetate Nutrition 18 747 750 10.1016/S0899-9007(02)00825-0 12297211
Wang Y Zhou Y Graves DT 2014 FOXO transcription factors: their clinical significance and regulation Biomed Res Int 2014 925350 4016844 --> 24864265
Webb AE Brunet A 2014 FOXO transcription factors: key regulators of cellular quality control Trends Biochem Sci 39 159 169 10.1016/j.tibs.2014.02.003 4021867 --> 24630600
Welborn JR Shpun S Dantzler WH Wright SH 1998 Effect of α-ketoglutarate on organic anion transport in single rabbit renal proximal tubules Am J Physiol Renal Physiol 274 F165 F174
Wernerman J Hammarqvist F Vinnars E 1990 α-Ketoglutarate and postoperative muscle catabolism Lancet 335 701 703 10.1016/0140-6736(90)90811-I 1969067
Wirén M Permert J 2002 α-ketoglutarate-supplemented enteral nutrition: effects on postoperative nitrogen balance and muscle catabolism Nutrition 18 725 728 10.1016/S0899-9007(02)00844-4 12297206
Wu G Fang YZ Yang S Lupton JR Turner ND 2004 Glutathione metabolism and its implications for health J Nutr 134 489 492 14988435
Wullschleger S Loewith R Hall MN 2006 TOR signaling in growth and metabolism Cell 124 471 484 10.1016/j.cell.2006.01.016 16469695
Yeh SL Lai YN Shang HF Lin MT Chen WJ 2004 Effects of glutamine supplementation on innate immune response in rats with gut-derived sepsis Br J Nutr 91 423 430 10.1079/BJN20031069 15005828
Ziegler TR Daignault NM 2000 Glutamine regulation of human immune cell function Nutrition 16 458 459 10.1016/S0899-9007(00)00359-2 10869904
Zimmerman JJ Ringer TV 1992 Inflammatory host responses in sepsis Crit Care Clin 8 163 189 1732028
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