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NTIS 바로가기동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine, v.30 no.5, 2016년, pp.347 - 354
Lee, Ju Won (Department of Korean Medical Science, Graduate School of East-West Medical Science, Kyung Hee University)
This study evaluated the effects of Fructus Corni Officinalis water extract (FCE) on congnitive impairment and Aβ clearance induced by beta amyloid Aβ (1-42) injection in the hippocampus of rat. Aβ (1-42) was injected into the hippocampus using a Hamilton syringe and micropump (5 ㎍/5 ㎕, 1 ㎕/min, eac...
Blennow, K., de Leon, M.J., Zetterberg, H. Alzheimer’s disease. Lancet 368(9533):387-403, 2006.
Dickson, D.W. The pathogenesis of senile plaques. J Neuropathol Exp Neurol 56(4):321-339, 1997.
Yates, S.L., Burgess, L.H., Kocsis-Angle, J., Antal, J.M., Dority, M.D., Embury, P.B., et al. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J Neurochem. 74(3):1017-1025, 2000.
Selkoe, D.J., Schenk, D. Alzheimer’s disease: Molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol. 43: 545-584, 2003.
Liu, H., Xing, A., Wang, X., Liu, G., Li, L. Regulation of β-amyloid level in the brain of rats with cerebrovascular hypoperfusion. Neurobiol Aging. 33(826):31-42, 2012.
Wang, Y.J., Zhou, H.D., Zhou, X.F. Clearance of amyloid-beta in Alzheimer's disease: progress, problemsand perspectives. Drug Discov Today. 11(20):931-938, 2006.
Donahue, J.E., Flaherty, S.L., Johanson, C.E., Duncan, J.A.3rd, Silverberg, G.D., Miller, M.C., Tavares, R., Yang, W., Wu, Q., Sabo, E., Hovanesian, V., Stopa, E.G. RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease. Acta Neuropathol. 112(4):405-415, 2006.
Scripnikov, A., Khomenko, A., Napryeyenko, O. GINDEM-NP Study Group. Effects of Ginkgo biloba extract EGb 761 on neuropsychiatric symptoms of dementia: findings from a randomised controlled trial. Wien Med Wochenschr. 157(13):295-300, 2007.
Han, Y., Jung, H.W., Park, Y.K. Selective therapeutic effect of cornus officinalis fruits on the damage of different organs in STZ-induced diabetic rats. Am J Chin Med. 42(5):1169-1182, 2014.
Jeong, E.J., Kim, T.B., Yang, H., Kang, S.Y., Kim, S.Y., Sung, S.H., Kim, Y.C. Neuroprotective iridoid glycosides from Cornus officinalis fruits against glutamate-induced toxicity in HT22 hippocampal cells. Phytomedicine. 15(19):317-321, 2012.
Wang, W., Sun, F., An, Y., Ai, H., Zhang, L., Huang, W., Li, L. Morroniside protects human neuroblastoma SH-SY5Y cells against hydrogen peroxide-induced cytotoxicity. Eur J Pharmacol. 24(613):19-23, 2009.
Hong, S.Y., Jeong, W.S., Jun, M. Protective effects of the key compounds isolated from Corni fructus against β-amyloid-induced neurotoxicity in PC12 cells. Molecules. 10(17):10831-10845, 2012.
Blennow, K., de Leon, M.J., Zetterberg, H. Alzheimer's disease. Lancet. 29;368(9533):387-403, 2006.
Dickson, D.W. The pathogenesis of senile plaques. J Neuropathol Exp Neurol. 56(4):321-339. 1997.
Grundke-Iqbal, I., Iqbal, K., Quinlan, M., Tung, Y.C., Zaidi, M.S., Wisniewski, H.M. Microtubule-associated protein tau. A component of alzheimer paired helical filaments. J Biol Chem. 5;261(13):6084-6089, 1986.
Ball, M.J. Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia. A quantitative study. Acta Neuropathol. 28;37(2):111-118, 1977.
Kuhl, D.E., Koeppe, R.A., Minoshima, S., Snyder, S.E., Ficaro, E.P., Foster, N.L., et al. In vivo mapping of cerebral acetylcholinesterase activity in aging and alzheimer's disease. Neurology. 10;52(4):691-699, 1999.
Selkoe, D.J. Amyloid beta-protein and the genetics of alzheimer's disease. J Biol Chem. 2;271(31):18295-19298, 1996.
Cacquevel, M., Lebeurrier, N., Cheenne, S., Vivien, D. Cytokines in neuroinflammation and alzheimer's disease. Curr Drug Targets. 5(6):529-534, 2004.
Berezovska, O., Lleo, A., Herl, L.D., Frosch, M.P., Stern, E.A., Bacskai, B.J., et al. Familial alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein. J Neurosci. 16;25(11):3009-3017, 2005.
Mhatre, M., Floyd, R.A., Hensley, K. Oxidative stress and neuroinflammation in alzheimer's disease and amyotrophic lateral sclerosis: Common links and potential therapeutic targets. J Alzheimers Dis. 6(2):147-157, 2004.
Roberson, M.R., Kolasa, K., Parsons, D.S., Harrell, L.E. Cholinergic denervation and sympathetic ingrowth result in persistent changes in hippocampal muscarinic receptors. Neuroscience. 80(2):413-418, 1997.
De Ferrari, G.V., Canales, M.A., Shin, I., Weiner, L.M., Silman, I., Inestrosa, N.C. A structural motif of acetylcholinesterase that promotes amyloid beta-peptide fibril formation. Biochemistry. 4;40(35):10447-10457, 2001.
Deane, R., Bell, R., Sagare, A., Zlokovic, B. Clearance of amyloid-β peptide across the blood-brain barrier: Implication for therapies in Alzheimer’s disease. CNS & neurological disorders drug targets. 8(1):16-30, 2009.
Ramanathan, A., Nelson, A., Sagare, A., Zlokovic, B. Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer’s disease: The role, regulation and restoration of LRP1. Frontiers in Aging Neuroscience. 7: 136, 2015.
Bell, R.D., Sagare, A.P., Friedman, A.E., Bedi, G.S., Holtzman, D.M., Deane, R., et al. Transport pathways for clearance of human Alzheimer’s amyloid beta-peptideand apolipoproteins E and J in the mouse centralnervous system. J Cereb Blood Flow Metab. 27: 909-918, 2007.
Deane, R., Wu, Z., Sagare, A., Davis, J., Du Yan, S., Hamm, K., et al. LRP/amyloid beta-peptide interaction mediates differential brain efflux of Aβ isoforms. Neuron. 43: 333-344, 2004.
Wang, R., Zhang, Y., Li, J., Zhang, C. Resveratrol ameliorates spatial learning memory impairment induced by Aβ1-42 in rats. Neuroscience. S0306-4522(16)30433-X. 2016.
Ashabi, G., Alamdary, S.Z., Ramin, M., Khodagholi, F. Reduction of hippocampal apoptosis by intracerebroventricular administration of extracellular signal-regulated protein kinase and/or p38 inhibitors in amyloid beta rat model of Alzheimer's disease: involvement of nuclear-related factor-2 and nuclear factor-κB. Basic Clin Pharmacol Toxicol. 112(3):145-155, 2013.
Lecanu, L., Greeson, J., Papadopoulos, V. Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain. Pharmacology. 76: 19-33, 2006.
Kamenetz, F., Tomita, T., Hsieh, H., Seabrook, G., Borchelt, D., Iwatsubo, T., Sisodia, S., Malinow, R. APP processing and synaptic function. Neuron. 37: 925-937, 2003.
Donahue, J.E., Flaherty, S.L., Johanson, C.E., Duncan, J.A.3rd, Silverberg, G.D., Miller, M.C., Tavares, R., Yang, W., Wu, Q., Sabo, E., Hovanesian, V., Stopa, E.G. RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease. Acta Neuropathol. 112(4):405-415, 2006.
Shibata, M., Yamada, S., Kumar, S., Calero, M., Bading, J., Frangione, B., Holtzman, D., Miller, C., Strickland, D., Ghiso, J., Zlokovic, B. Clearance of Alzheimer’s amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest 106: 1489-1499, 2000.
Tamaki, C., Ohtsuki, S., Iwatsubo, T., Hashimoto, T., Yamada, K., Yabuki, C. Major involvement of low-density lipoprotein receptor-related protein 1 in the clearance of plasma free amyloid beta-peptide by the liver. Pharm. Res. 23: 1407-1416, 2006.
Bell, R.D., Sagare, A.P., Friedman, A.E., Bedi, G.S., Holtzman, D.M., Deane, R. Transport pathways for clearance of human Alzheimer’s amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system. J. Cereb. Blood Flow Metab. 27: 909-918, 2007.
Sagare, A., Deane, R., Bell, R.D., Johnson, B., Hamm, K., Pendu, R. Clearance of amyloid-beta by circulating lipoprotein receptors. Nat. Med. 13: 1029-1031, 2007.
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