[논문]Platelet rich fibrin in the management of established dry socket

Chakravarthi, Srinivas

doi:10.5125/jkaoms.2017.43.3.160

Platelet rich fibrin in the management of established dry socket 원문보기

Journal of the Korean Association of Oral and Maxillofacial Surgeons, v.43 no.3, 2017년, pp.160 - 165

Chakravarthi, Srinivas (Department of Oral and Maxillofacial Surgery, Sibar Institute of Dental Sciences)

Abstract ▼ AI-Helper

Objectives: Dry socket may occur secondary to the removal of any tooth. However, most dry socket cases develop in the third molar region. Dry socket is multifactorial in nature and has been treated using various modalities with varying success rates. This study assessed the efficacy of platelet rich fibrin (PRF) in established dry socket. Materials and Methods: Ten patients of either sex aged from 41 to 64 years with established dry socket according to established criteria were treated using PRF. Evaluation was performed by observing the reduction of pain using visual analogue scale, analgesic tablet use over the follow-up period, and healing parameters. Results: Pain was reduced on the first day in all patients with decreased analgesic use. Pain was drastically reduced during follow-up on the first, second, third, and seventh days with a fall in pain score of 0 to 1 after the first day alone. The pain scores of all patients decreased to 1 by the first day except in one patient, and the scores decreased to 0 in all patients after 48 hours. Total analgesic intake ranged from 2 to 6 tablets (aceclofenac 100 mg per tablet) over the follow-up period of 7 days. Healing was satisfactory in all patients by the end of the seventh day. Conclusion: PRF showed early pain reduction in established dry socket with minimal analgesic intake. No patients had allergic reactions to PRF as it is derived from the patient's own blood. PRF showed good wound healing. Our study suggests that PRF should be considered as a treatment modality for established dry socket.

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문제 정의

This study assessed second generation platelet rich growth factors (PRGF)—platelet rich fibrin (PRF) in the management of established dry socket.

가설 설정

¹³ studied 45 patients divided into three groups (15 each) and showed better healing and reduced symptoms with zinc oxide eugenol (ZOE) and gelatin-soaked sponge with PRGF compared to conventional irrigation with saline. The study also suggested that use of PRGF with gelatin might be an appropriate management choice. Haraji et al.

제안 방법

(Fig. 1) Clinical parameters were assessed on the first, second, third, seventh, and fifteenth days postoperatively for reduction in pain, analgesic intake, and satisfactory wound healing. Aceclofenac 100 mg tab was prescribed for all patients.
We have not compared sex differences but the literature shows a higher incidence of dry socket in females⁶. This study did not have control groups for comparison as this was a preliminary case series with 15 days of follow-up for clinical examination. A randomized, blind, multicenter longterm study with histopathological examination is needed to confirm the nature of new bone formed during implant placement.

대상 데이터

. Our study included only 10 patients in a single center. We have not compared sex differences but the literature shows a higher incidence of dry socket in females⁶.
The study included 10 patients with aged from 41 to 64 years of either sex with dry socket diagnosis established according to the criteria of inclusion and were willing to participate in the PRF treatment protocol. Patients were enrolled from July to December 2015, the defined period of study. Patient complaints falling within the criteria of dry socket included major symptoms like continuous throbbing pain radiating to the ear, temple, and neck, start of pain 1 to 3 days post extraction, foul taste, bad breath, pain not relieved even after medication, and signs including devoid of blood clot, infected or retained roots, localized swelling, and lymphadenopathy.
The study consisted of a total of ten patients (5 males and 5 females).(Table 2) Pain for all patients decreased to 1 by the first day except in one patient and decreased to 0 after 48 hours in all patients.
The study included 10 patients with aged from 41 to 64 years of either sex with dry socket diagnosis established according to the criteria of inclusion and were willing to participate in the PRF treatment protocol. Patients were enrolled from July to December 2015, the defined period of study.

데이터처리

Data were tabulated using Microsoft excel (Microsoft, Redmond, WA, USA) and statistical analysis was carried out using the mean, percentage, Mann-Whitney test, Kruskal-Wallis test, and paired t-test. For statistical analysis, IBM SPSS Statistics ver.

성능/효과

Such patients having a minimum of two symptoms and one sign were considered as established dry socket. (Table 1) Patients willing to participate in the treatment protocol using PRF were postoperatively assessed for various parameters like reduction of pain using visual analogue scale, reduction in analgesic use, and reduced symptoms and signs were noted. Those not willing to undergo PRF treatment were excluded from the study and were managed with other conventional modalities.

참고문헌 (36)

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표제어: PCR

동의어: Packet Collision Rate

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용어 설명: PCR은 세균 특이성이 있는 primer를 이용하여 적은 수의 세균이 있을지라도 쉽게 검출할 수 있는 유용한 방법이며, 이를 이용하여 구강 내 치면세균막이나 타액에서 직접 세균을 검출할 수 있게 되었다[8].

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연합인증

Platelet rich fibrin in the management of established dry socket 원문보기

Abstract ▼ AI-Helper

주제어

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문제 정의

가설 설정

제안 방법

대상 데이터

데이터처리

성능/효과

참고문헌 (36)

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Platelet rich fibrin in the management of established dry socket 원문보기

Abstract ▼ AI-Helper

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문제 정의

가설 설정

제안 방법

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참고문헌 (36)

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